Gene: Ewsr1

Name Ewing sarcoma breakpoint region 1

Synonyms Ews

Status ES CellsMice
phenotype data available

Links MGI:99960   Ensembl Gene   Ensembl Orthologs

Viability Homozygous - Lethal

Phenotype associations for Ewsr1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Ewsr1 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
Sternum - developmental and structural abnormality Ewsr1tm1b(EUCOMM)Wtsi HET Female postnatal 0.0
edema Ewsr1tm1b(EUCOMM)Wtsi HET Female Male embryonic day 15.5 0.0
edema Ewsr1tm1b(EUCOMM)Wtsi HOM Female Male embryonic day 15.5 0.0
preweaning lethality, complete penetrance Ewsr1tm1b(EUCOMM)Wtsi HOM Female Male n/a 0.0
increased or absent threshold for auditory brainstem response Ewsr1tm1b(EUCOMM)Wtsi HET Female postnatal 3.66E-9
short tibia Ewsr1tm1b(EUCOMM)Wtsi HET Female Male postnatal 3.22E-8
decreased lean body mass Ewsr1tm1b(EUCOMM)Wtsi HET Female Male postnatal 2.79E-7
hyperactivity Ewsr1tm1b(EUCOMM)Wtsi HET Female Male postnatal 6.48E-6
abnormal bone structure Ewsr1tm1b(EUCOMM)Wtsi HET Female Male postnatal 1.67E-5

Download data as: TSV XLS


IMPC lacZ Expression Data
No expression data was found for this adult tab
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 6 (5/439) Image Only
Ear 6 Image Only
Embryo 6 (9/9)
Eye 6 Image Only
Foot 6 Image Only
Forebrain 6 Image Only
Forelimb 6 Image Only
Hand 6 Image Only
Head 6 (4/439) Image Only
Heart 6 Image Only
Hindbrain 6 (5/439) Image Only
Hindlimb 6 Image Only
Liver 6 Image Only
Lung 6 Image Only
Mandibular process 6 Image Only
Maxillary process 6 Image Only
Midbrain 6 Image Only
Oral cavity 6 Image Only
1 (11/26) (1/1)
Skin 6 Image Only
Tail 6 Image Only
Tail somite 6 Image Only

Associated Images

Associated Images
  • Embryo LacZ: LacZ images wholemount
    36 Images
  • Gross Pathology and Tissue Collection
    8 Images
  • X-ray: XRay Images Skull Lateral Orientation
    10 Images
  • X-ray: XRay Images Lateral Orientation
    10 Images
  • Eye Morphology: Images Ophthalmoscopy
    1 Images
  • Histopathology
    1 Images

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Ewsr1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Ewsr1tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre)
Ewsr1tm1(NCOM)Mfgc Reporter-tagged deletion allele (with selection cassette)