Gene: Pax5


Name paired box 5

  • Pax-5
  • EBB-1

Status ES CellsMice
phenotype data available

Links MGI:97489    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Pax5

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Pax5 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
hyperactivity Pax5tm1b(EUCOMM)Wtsi HET Female Male postnatal 2.61E-6
decreased leukocyte cell number Pax5tm1b(EUCOMM)Wtsi HET Female Male postnatal 4.86E-6
increased cardiac muscle contractility Pax5tm1b(EUCOMM)Wtsi HET Female Male postnatal 7.04E-6
increased circulating triglyceride level Pax5tm1b(EUCOMM)Wtsi HET Male postnatal 1.25E-5
impaired glucose tolerance Pax5tm1b(EUCOMM)Wtsi HET Female Male postnatal 3.29E-5
decreased threshold for auditory brainstem response Pax5tm1b(EUCOMM)Wtsi HET Female Male postnatal 6.13E-5
preweaning lethality, complete penetrance Pax5tm1b(EUCOMM)Wtsi HOM Female Male n/a 1.0E-4

Download data as: TSV XLS


Expression data not available

Associated Images

Associated Images
  • X-ray: XRay Images Lateral Orientation
    3 Images
  • X-ray: XRay Images Dorso Ventral
    3 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Pax5tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Pax5tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre)