Gene: Mag

Order

Name myelin-associated glycoprotein

Synonyms
  • siglec-4a
  • Gma

Status ES CellsMice
tm1
Mice
tm1.1
phenotype data available

Links MGI:96912    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Mag

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Mag data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
convulsive seizures Magtm1.1(KOMP)Vlcg HOM Female Male postnatal 4.06E-24
decreased startle reflex Magtm1.1(KOMP)Vlcg HOM Female Male postnatal 2.13E-10
abnormal sleep behavior Magtm1.1(KOMP)Vlcg HOM Female Male postnatal 4.81E-9
decreased total body fat amount Magtm1.1(KOMP)Vlcg HOM Female Male postnatal 1.31E-6
decreased coping response Magtm1.1(KOMP)Vlcg HOM Female Male postnatal 3.14E-6
decreased circulating glucose level Magtm1.1(KOMP)Vlcg HOM Female Male postnatal 6.04E-6
decreased circulating triglyceride level Magtm1.1(KOMP)Vlcg HOM Female Male postnatal 1.66E-5
decreased circulating insulin level Magtm1.1(KOMP)Vlcg HOM Female Male postnatal 3.16E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (5/393)
Aorta 2 No (1/562)
Brain 2 No (6/562) (2/2)
Brainstem 2 No (4/562) (2/2)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/562)
Cerebellum 2 No (4/562) (2/2)
Cerebral cortex 2 No (5/562) (2/2)
Epididymis 2 No (4/106)
Esophagus 2 No (2/393)
Eye 2 No (1/562) (2/2)
Heart 2 No (3/562)
Hippocampus 2 No (5/562) (2/2)
Hypothalamus 2 No (4/562) (2/2)
Kidney 2 No (20/562)
Large intestine 2 No (12/562)
Liver 2 No
Lower urinary tract 2 No (3/562)
Lung 2 No (3/562)
Lymph node 2 No (1/562)
Mammary gland 2 No
Midbrain 2 No (2/2)
Olfactory lobe 2 No (4/393) (2/2)
Ovary 2 No (1/562) (1/2)
Oviduct 2 No (2/562)
Pancreas 2 No (6/562)
Peripheral nervous system 2 No (3/562) (2/2)
Peyer's patch 2 No (1/393)
Pituitary gland 2 No (1/562) (2/2)
Prostate gland 2 No (5/562)
Skeletal muscle 2 No
Skin 2 No (1/562)
Small intestine 2 No (11/562)
Spinal cord 2 No (3/562) (2/2)
Spleen 2 No (4/562)
Stomach 2 No (9/562)
Striatum 2 No (4/562) (2/2)
Submandibular gland 2 No (1/104)
Testis 2 No (4/562)
Thalamus 2 No (2/2)
Thymus 2 No
Thyroid gland 2 No (16/562)
Trachea 2 No (3/562)
Urinary bladder 2 No
Uterus 2 No (2/562)
Vascular system 2 No (1/393)
Vesicular gland 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse
    nervous system
    sensory organ
    reproductive system
    trunk
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2 (6/482)
Dorsal root ganglion 2 (1/45)
Ear 2 (1/482)
Embryo 2 (1/482)
Eye 2 (1/482)
Foot 2 (1/482)
Forebrain 2 (1/482)
Forelimb 2 (1/482)
Fronto-nasal process 2 (1/46)
Hand 2 (1/482)
Head 2 (5/482)
Heart 2 (1/482)
Hindbrain 2 (6/482)
Hindlimb 2 (1/482)
Liver 2 (1/482)
Lung 2 (1/482)
Mandibular process 2 (1/482)
Maxillary process 2 (1/482)
Midbrain 2 (1/482)
Nose 2 (1/47)
Oral cavity 2 (1/482)
Skin 2 (1/482)
Spinal cord 2 (1/46)
Tail 2 (1/482)
Tail somite 2 (1/482)


Associated Images

Associated Images
  • X-ray: XRay Images Lateral Orientation
    10 Images
  • X-ray: XRay Images Dorso Ventral
    10 Images
  • X-ray: XRay Images Skull Lateral Orientation
    10 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    10 Images
  • Electroretinography 2: Rod and cone PDF
    4 Images
  • Sleep Wake: Wake state (bmp file)
    7 Images
  • X-ray: XRay Images Forepaw
    10 Images

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Magtm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene
Magtm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette)
Vector
Gene
Magtm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene