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Gene: Hoxa6 MGI:96178

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Not currently registered for phenotyping at IMPC

Phenotyping is currently not planned for a knockout strain of this gene.

Gene Summary

Name:
homeobox A6
Synonyms:
Hox-1.2

Order Alleles

IMPC Data Collections

  • No Body Weight Data
  • No Embryo Imaging Data
  • No Viability Data

IMPC Phenotype Summary

Significant
Not Significant
Not tested

View all our phenotype data below

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Hoxa6 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Hoxa6 by phenotypic similarity.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Cervical Rib
Cervical ribs OMIM:117900
Neurogenic Thoracic Outlet Syndrome
Abnormal rib morphology ORPHA:100073
Spondylocostal Dysostosis 2, Autosomal Recessive
Hemivertebrae, Vertebral segmentation defect, Vertebral clefting, Rib fusion, Short neck OMIM:608681
Spondylocostal Dysostosis 3, Autosomal Recessive
Supernumerary vertebral ossification centers, Scoliosis, Vertebral segmentation defect, Kyphosis,... OMIM:609813
Sprengel Deformity
Cervical segmentation defect, Spina bifida occulta, Scoliosis, Hemivertebrae, Sprengel anomaly, R... OMIM:184400
Radioulnar Synostosis-Microcephaly-Scoliosis Syndrome
Pectus carinatum, Scoliosis, Abnormal rib morphology, Radioulnar synostosis, Abnormality of the e... ORPHA:3268
Spondylocostal Dysostosis 5
Butterfly vertebrae, Pectus carinatum, Scoliosis, Hemivertebrae, Missing ribs, Supernumerary ribs... OMIM:122600
Hypo- And Hypermelanotic Cutaneous Macules-Retarded Growth-Intellectual Disability Syndrome
Abnormal rib morphology ORPHA:2435
Klippel-Feil Syndrome 3, Autosomal Dominant
Cervical C3/C4 vertebral fusion, Cervical C5/C6 vertebrae fusion, Thoracic scoliosis OMIM:613702
Thoracic Dysostosis, Isolated
Short ribs, Bell-shaped thorax, Pectus excavatum OMIM:187750
Thoracomelic Dysplasia
Short ribs, Bell-shaped thorax OMIM:273740
Hypogonadism, Male, With Mental Retardation And Skeletal Anomalies
Abnormality of the cervical spine, Superior rib anomalies OMIM:307500
Short-Rib Thoracic Dysplasia 17 With Or Without Polydactyly
Lateral clavicle hook, Narrow chest, Short ribs, Acetabular spurs, Trident acetabulum, Horizontal... OMIM:617405
Heart Defects-Limb Shortening Syndrome
Kyphosis, Abnormal rib morphology, Narrow chest, Abnormal form of the vertebral bodies ORPHA:1354
Becker Nevus Syndrome
Scoliosis, Hemivertebrae, Pectus excavatum, Cervical ribs OMIM:604919
Kyphomelic Dysplasia
Lateral clavicle hook, Narrow chest, Abnormal form of the vertebral bodies, Short thorax, Undulat... ORPHA:1801
Endosteal Hyperostosis, Worth Type
Clavicular sclerosis, Sclerotic vertebral body, Abnormal rib morphology, Abnormal form of the ver... ORPHA:2790
Spondylocostal Dysostosis 1, Autosomal Recessive
Kyphoscoliosis, Abnormal odontoid process morphology, Hemivertebrae, Vertebral segmentation defec... OMIM:277300
Autosomal Dominant Spondylocostal Dysostosis
Spina bifida occulta, Short thorax, Scoliosis, Hyperlordosis, Vertebral segmentation defect, Miss... ORPHA:1797
Spondylometaphyseal Dysplasia, A4 Type
Platyspondyly, Flared, irregular rib ends ORPHA:168555
Thoracolaryngopelvic Dysplasia
Bell-shaped thorax, Scoliosis, Short ribs, Irregular chondrocostal junctions, Irregular vertebral... OMIM:187760
Osteogenesis Imperfecta, Type Ix
Platyspondyly, Pectus carinatum, Scoliosis, Pectus excavatum, Kyphosis, Wormian bones, Multiple r... OMIM:259440
Isolated Klippel-Feil Syndrome
Abnormal shoulder morphology, Cervical C2/C3 vertebral fusion, Abnormality of the vertebral colum... ORPHA:2345
Diaphanospondylodysostosis
Absent or minimally ossified vertebral bodies, Short thorax, Enlarged thorax, Missing ribs, Short... ORPHA:66637
Mesomelic Dysplasia, Kantaputra Type
Tarsal synostosis, Cubitus valgus, Vertebral segmentation defect, Synostosis of carpal bones, Abn... ORPHA:1836
Metatropic Dysplasia
Abnormal intervertebral disk morphology, Narrow chest, Abnormal form of the vertebral bodies, Sco... ORPHA:2635
Spondyloepimetaphyseal Dysplasia With Joint Laxity, Type 3
Multiple joint dislocation, Carpal bone hypoplasia, Platyspondyly, Dislocated radial head, Thin r... OMIM:618395
Hypersulfaturia
Costochondral pain OMIM:620372
Mayer-Rokitansky-Küster-Hauser Syndrome Type 2
Short neck, Vertebral segmentation defect, Abnormal rib morphology ORPHA:2578
Klippel-Feil Syndrome 2, Autosomal Recessive
Fused cervical vertebrae, Cervical C2/C3 vertebral fusion, Scoliosis, Sprengel anomaly, Short neck OMIM:214300
Congenital Pseudoarthrosis Of The Clavicle
Congenital pseudoarthrosis of the clavicle, Osteoarthritis, Cervical ribs ORPHA:66630
X-Linked Skeletal Dysplasia-Intellectual Disability Syndrome
Scoliosis, Abnormal sacrum morphology, Fused cervical vertebrae, Thoracic hemivertebrae ORPHA:1436
Male Hypergonadotropic Hypogonadism-Intellectual Disability-Skeletal Anomalies Syndrome
Abnormal form of the vertebral bodies, Hemivertebrae, Abnormal rib morphology, Abnormality of the... ORPHA:2234
Short-Rib Thoracic Dysplasia 11 With Or Without Polydactyly
Lateral clavicle hook, Bell-shaped thorax, Narrow chest, Thoracic dysplasia, Horizontal ribs OMIM:615633
Spondyloepimetaphyseal Dysplasia, Irapa Type
Limited elbow extension, Hypoplastic sacrum, Genu valgum, Enlargement of the costochondral juncti... OMIM:271650
Craniodiaphyseal Dysplasia
Abnormal rib morphology ORPHA:1513
Pierre Robin Sequence With Pectus Excavatum And Rib And Scapular Anomalies
Hypoplastic distal segments of scapulae, Pectus excavatum, Abnormal rib morphology OMIM:602196
Poland Syndrome
Hemivertebrae, Sprengel anomaly, Short ribs, Rib fusion OMIM:173800
Microcephaly-Cervical Spine Fusion Anomalies Syndrome
Abnormal clavicle morphology, Fused cervical vertebrae, Hyperlordosis, Pectus excavatum, Abnormal... ORPHA:2522
Metatropic Dysplasia
Kyphoscoliosis, Caudal appendage, Genu valgum, Narrow chest, Relatively short spine, Scoliosis, S... OMIM:156530
Osteogenesis Imperfecta, Type Xv
Scoliosis, Thin ribs, Platyspondyly OMIM:615220
Spondylocostal Dysostosis 4, Autosomal Recessive
Abnormal odontoid process morphology, Bell-shaped thorax, Spina bifida occulta, Short thorax, Sco... OMIM:613686
Becker Nevus Syndrome
Spina bifida occulta, Pectus carinatum, Scoliosis, Pectus excavatum, Kyphosis, Supernumerary ribs... ORPHA:64755
Fibrochondrogenesis 2
Bell-shaped thorax, Short ribs, Cupped ribs, Thoracic hypoplasia, Platyspondyly OMIM:614524
Spondyloepimetaphyseal Dysplasia, Irapa Type
Abnormal carpal morphology, Genu valgum, Pectus carinatum, Synostosis of carpal bones, Abnormal r... ORPHA:93351
Thoracic Outlet Syndrome
Abnormal rib morphology ORPHA:97330
Mental Retardation, Skeletal Dysplasia, And Abducens Palsy
Scoliosis, Fused cervical vertebrae, Thoracic hemivertebrae, Prominent metopic ridge OMIM:309620
Spondylomegaepiphyseal Dysplasia With Upper Limb Mesomelia, Punctate Calcifications, And Deafness
Beaking of vertebral bodies, Scoliosis, Delayed ossification of carpal bones, Flat acetabular roo... OMIM:609616
Thin Ribs-Tubular Bones-Dysmorphism Syndrome
Abnormal rib morphology ORPHA:1506
Axial Spondylometaphyseal Dysplasia
Aplasia/Hypoplasia of the vertebrae, Narrow chest, Delayed ossification of carpal bones, Short ri... ORPHA:168549
Klippel-Feil Syndrome 1, Autosomal Dominant
Cervical C2/C3 vertebral fusion, Scoliosis, Abnormal rib morphology, Sprengel anomaly, Short neck... OMIM:118100
Contractures, Pterygia, And Spondylocarpotarsal Fusion Syndrome 1B
Tarsal synostosis, Fused cervical vertebrae, Scoliosis, Antecubital pterygium, Fused thoracic ver... OMIM:618469
Cloverleaf Skull-Multiple Congenital Anomalies Syndrome
Abnormal clavicle morphology, Narrow chest, Abnormal rib morphology, Platyspondyly, Short neck ORPHA:93267
Grant Syndrome
Narrow chest, Joint dislocation, Abnormal rib morphology, Sprengel anomaly, Wormian bones, Abnorm... ORPHA:2097
Mosaic Trisomy 14
Camptodactyly of finger, Narrow chest, Short neck, Abnormal rib morphology ORPHA:1703
Autosomal Recessive Spondylocostal Dysostosis
Abnormal intervertebral disk morphology, Spina bifida occulta, Abnormal form of the vertebral bod... ORPHA:2311
Lethal Congenital Contracture Syndrome Type 1
Abnormality of the elbow, Short neck, Abnormal rib morphology, Abnormal form of the vertebral bodies ORPHA:1486
Mucopolysaccharidosis, Type X
Beaking of vertebral bodies, Genu valgum, Spatulate ribs, Broad clavicles, Scoliosis, Hyperlordos... OMIM:619698
Jeune Syndrome
Abnormal clavicle morphology, Narrow chest, Short thorax, Abnormal sternum morphology, Abnormal r... ORPHA:474
Laryngotracheoesophageal Cleft Type 4
Abnormal rib morphology, Abnormal form of the vertebral bodies ORPHA:93941
10Q22.3Q23.3 Microduplication Syndrome
Abnormal clavicle morphology, Abnormal rib morphology ORPHA:276422
Mucopolysaccharidosis, Type Iva
Genu valgum, Lumbar kyphosis, Anterior beaking of lumbar vertebrae, Pectus carinatum, Scoliosis, ... OMIM:253000
Juberg-Hayward Syndrome
Abnormality of the wrist, Abnormal vertebral morphology, Scoliosis, Abnormal rib morphology, Radi... ORPHA:2319
Dyggve-Melchior-Clausen Disease
Limited elbow extension, Beaking of vertebral bodies, Genu valgum, Abnormality of the vertebral c... ORPHA:239
Hydrocephalus-Costovertebral Dysplasia-Sprengel Anomaly Syndrome
Abnormal form of the vertebral bodies, Scoliosis, Hemivertebrae, Abnormal rib morphology, Sprenge... ORPHA:2180
Schneckenbecken Dysplasia
Lateral clavicle hook, Narrow chest, Short ribs, Flat acetabular roof, Narrow vertebral interpedi... OMIM:269250
Septopreoptic Holoprosencephaly
Abnormal vertebral morphology, Abnormal rib morphology ORPHA:280195
Diastrophic Dysplasia
Abnormal clavicle morphology, Joint dislocation, Abnormal form of the vertebral bodies, Scoliosis... ORPHA:628
Achondrogenesis Type 1B
Short thorax, Short neck, Narrow chest, Abnormal rib morphology ORPHA:93298
Mucopolysaccharidosis Type 4
Genu valgum, Joint dislocation, Short thorax, Pectus carinatum, Scoliosis, Hyperlordosis, Abnorma... ORPHA:582
White Forelock With Malformations
Sprengel anomaly, Spina bifida occulta, Abnormal rib morphology ORPHA:2475
Mullerian Duct Aplasia, Unilateral Renal Agenesis, And Cervicothoracic Somite Anomalies
Sprengel anomaly, Abnormal rib morphology, Abnormality of the vertebral column OMIM:601076
Fibrochondrogenesis
Bell-shaped thorax, Narrow chest, Abnormal form of the vertebral bodies, Short ribs, Abnormal rib... ORPHA:2021
Femoral-Facial Syndrome
Scoliosis, Vertebral segmentation defect, Abnormal rib morphology, Rib fusion, Sprengel anomaly, ... ORPHA:1988
Holt-Oram Syndrome
Abnormal clavicle morphology, Scoliosis, Pectus excavatum, Abnormal rib morphology, Kyphosis, Spr... ORPHA:392
Imperforate Oropharynx-Costovertebral Anomalies Syndrome
Missing ribs, Hemivertebrae, Abnormal rib morphology, Abnormal form of the vertebral bodies ORPHA:2759
Osteogenesis Imperfecta, Type Ii
Platyspondyly, Bell-shaped thorax, Thin ribs, Thoracic hypoplasia, Wormian bones, Multiple rib fr... OMIM:166210
Spondylocostal Dysostosis With Anal Atresia And Urogenital Anomalies
Thin ribs, Short ribs, Scoliosis, Hemivertebrae, Missing ribs, Block vertebrae, Rib fusion, Short... OMIM:271520
Platyspondylic Lethal Skeletal Dysplasia, Torrance Type
Narrow chest, Thin ribs, Short ribs, Flat acetabular roof, Wafer-thin platyspondyly, Ovoid verteb... OMIM:151210
Cat-Eye Syndrome
Abnormal rib morphology ORPHA:195
3M Syndrome
Increased vertebral height, Short thorax, Thin ribs, Enlarged thorax, Scapular winging, Hyperlord... ORPHA:2616
Osteogenesis Imperfecta, Type Xviii
Wormian bones, Thin ribs, Biconcave vertebral bodies, Vertebral compression fracture OMIM:617952
Microcephalic Primordial Dwarfism, Toriello Type
Abnormal rib morphology ORPHA:2643
Phaver Syndrome
Butterfly vertebrae, Abnormal form of the vertebral bodies, Pterygium, Abnormal rib morphology, C... ORPHA:2876
Cole-Carpenter Syndrome
Abnormal form of the vertebral bodies, Scoliosis, Kyphosis, Abnormal rib morphology, Wormian bones ORPHA:2050
Hypophosphatasia
Craniosynostosis, Abnormal rib morphology, Narrow chest ORPHA:436
Cole-Carpenter Syndrome 2
Lambdoidal craniosynostosis, Platyspondyly, Thin ribs, Pectus excavatum, Kyphosis, Coronal cranio... OMIM:616294
Melnick-Needles Syndrome
Narrow chest, Short thorax, Short clavicles, Delayed cranial suture closure, Scoliosis, Abnormal ... ORPHA:2484
Osteogenesis Imperfecta, Type Iii
Thin ribs, Scoliosis, Kyphosis, Biconcave vertebral bodies, Protrusio acetabuli, Wormian bones OMIM:259420
Cooper-Jabs Syndrome
Camptodactyly of finger, Missing ribs, Scoliosis, Abnormal rib morphology ORPHA:1488
Achondrogenesis, Type Ia
Hypoplastic sacrum, Bell-shaped thorax, Barrel-shaped chest, Narrow chest, Short thorax, Broad cl... OMIM:200600
Fibrochondrogenesis 1
Long clavicles, Thin clavicles, Widely patent coronal suture, Thin ribs, Short ribs, Posterior ve... OMIM:228520
Intellectual Disability-Polydactyly-Uncombable Hair Syndrome
Pectus carinatum, Kyphosis, Short neck, Abnormal rib morphology ORPHA:3082
Cerebrofaciothoracic Dysplasia
Narrow chest, Scoliosis, Hemivertebrae, Vertebral segmentation defect, Rib fusion, Sprengel anoma... ORPHA:1394
Acro-Renal-Mandibular Syndrome
Abnormal clavicle morphology, Butterfly vertebrae, Pectus carinatum, Thin ribs, Scoliosis, Hemive... ORPHA:958
Prune Belly Syndrome
Scoliosis, Vertebral segmentation defect, Pectus excavatum, Abnormal rib morphology, Congenital h... ORPHA:2970
Axial Mesodermal Dysplasia Spectrum
Abnormal form of the vertebral bodies, Scoliosis, Vertebral segmentation defect, Missing ribs, Ab... ORPHA:1834
Osteogenesis Imperfecta, Type Xvi
Platyspondyly, Vertebral compression fracture, Narrow chest, Wormian bones, Multiple rib fractures OMIM:616229
Growth Delay-Hydrocephaly-Lung Hypoplasia Syndrome
Abnormally ossified vertebrae, Abnormal rib morphology ORPHA:3035
Mucolipidosis Iii Alpha/Beta
Carpal bone hypoplasia, Spondylolisthesis, Scoliosis, Short ribs, Kyphosis, Irregular carpal bone... OMIM:252600
Congenital Osteogenesis Imperfecta-Microcephaly-Cataracts Syndrome
Abnormal rib morphology ORPHA:2772
Osteogenesis Imperfecta, Type X
Genu valgum, Narrow chest, Vertebral compression fracture, Thin ribs, Scoliosis, Thoracic hypopla... OMIM:613848
Cenani-Lenz Syndrome
Abnormal form of the vertebral bodies, Scoliosis, Synostosis of joints, Synostosis of carpal bone... ORPHA:3258
Metaphyseal Dysostosis, Impaired Intellectual Development, And Conductive Deafness
Carpal bone hypoplasia, Genu valgum, Scoliosis, Short ribs, Cupped ribs, Irregular chondrocostal ... OMIM:250420
Craniosynostosis, Herrmann-Opitz Type
Craniosynostosis, Abnormal rib morphology ORPHA:2145
Microcephaly-Seizures-Intellectual Disability-Heart Disease Syndrome
Abnormal sternum morphology, Short ribs, Abnormal rib morphology, Broad ribs ORPHA:2519
Gorlin Syndrome
Bifid ribs, Abnormal vertebral morphology, Vertebral wedging, Scoliosis, Hemivertebrae, Abnormal ... ORPHA:377
Renpenning Syndrome
Sprengel anomaly, Pectus excavatum, Abnormal rib morphology ORPHA:3242
Intellectual Disability-Myopathy-Short Stature-Endocrine Defect Syndrome
Pectus carinatum, Hyperlordosis, Abnormal rib morphology ORPHA:3068
Chronic Recurrent Multifocal Osteomyelitis 2, With Periostitis And Pustulosis
Joint swelling, Flaring of rib cage, Fused cervical vertebrae, Broad ribs OMIM:612852
Rhizomelic Skeletal Dysplasia With Or Without Pelger-Huet Anomaly
Limited elbow extension, Genu valgum, Thoracic platyspondyly, Platyspondyly, Joint dislocation, H... OMIM:618019
Holzgreve Syndrome
Abnormally ossified vertebrae, Abnormal rib morphology ORPHA:2167
Familial Osteodysplasia, Anderson Type
Abnormal form of the vertebral bodies, Scoliosis, Missing ribs, Abnormal rib morphology, Kyphosis... ORPHA:2769
Antley-Bixler Syndrome
Narrow chest, Delayed cranial suture closure, Abnormal rib morphology, Camptodactyly of finger, E... ORPHA:83
Campomelia, Cumming Type
Abnormally ossified vertebrae, Abnormal rib morphology, Abnormal thorax morphology ORPHA:1318
Bent Bone Dysplasia Syndrome 2
Butterfly vertebrae, Hypoplastic acetabulae, Thin ribs, Short ribs, Short sternum, Coronal cleft ... OMIM:620076
Osteogenesis Imperfecta, Type Viii
Platyspondyly, Barrel-shaped chest, Vertebral compression fracture, Scoliosis, Thin ribs, Kyphosi... OMIM:610915
Lung Agenesis-Heart Defect-Thumb Anomalies Syndrome
Vertebral segmentation defect, Abnormal rib morphology ORPHA:1120
Cleidocranial Dysplasia
Genu valgum, Narrow chest, Spina bifida occulta, Abnormal sacrum morphology, Short clavicles, Sco... ORPHA:1452
Trisomy 13
Scoliosis, Narrow chest, Kyphosis, Abnormal rib morphology ORPHA:3378
Radio-Renal Syndrome
Abnormality of the elbow, Short neck, Abnormal rib morphology, Abnormal form of the vertebral bodies ORPHA:3015
Poland Syndrome
Finger symphalangism, Asymmetry of the thorax, Spina bifida occulta, Abnormal sternum morphology,... ORPHA:2911
Mosaic Trisomy 8
Narrow chest, Scoliosis, Vertebral segmentation defect, Abnormal rib morphology, Camptodactyly of... ORPHA:96061
Alagille Syndrome
Spina bifida occulta, Butterfly vertebral arch, Abnormal form of the vertebral bodies, Vertebral ... ORPHA:52
Kyphomelic Dysplasia
Lateral clavicle hook, Pterygium, Flat acetabular roof, Undulate ribs, Anterior rib cupping, Thor... OMIM:211350
Pyknoachondrogenesis
Short thorax, Enlarged thorax, Short ribs, Unossified sacrum, Poorly ossified vertebrae, Horizont... ORPHA:3003
Tetraamelia-Multiple Malformations Syndrome
Missing ribs, Abnormally ossified vertebrae, Abnormal rib morphology ORPHA:3301
Spondylometaphyseal Dysplasia, Sedaghatian Type
Platyspondyly, Narrow chest, Abnormal scapula morphology, Abnormal rib morphology ORPHA:93317
Cartilage-Hair Hypoplasia
Limited elbow extension, Biconvex vertebral bodies, Sacral dimple, Narrow chest, Abnormal form of... ORPHA:175
Hurler Syndrome
Abnormal clavicle morphology, Abnormal vertebral morphology, Scoliosis, Abnormal rib morphology, ... ORPHA:93473
Aspergillosis
Abnormal rib morphology, Abnormality of the vertebral column ORPHA:1163
Oculocerebrocutaneous Syndrome
Missing ribs, Abnormal rib morphology, Congenital hip dislocation ORPHA:1647
Multiple Pterygium-Malignant Hyperthermia Syndrome
Scoliosis, Pectus excavatum, Kyphosis, Abnormal rib morphology, Prominent metopic ridge, Camptoda... ORPHA:2215
Autosomal Dominant Popliteal Pterygium Syndrome
Popliteal pterygium, Scoliosis, Abnormal rib morphology ORPHA:1300
Vacterl/Vater Association
Abnormal sacrum morphology, Abnormal intervertebral disk morphology, Abnormal rib morphology, Ver... ORPHA:887
Schwartz-Jampel Syndrome
Spinal rigidity, Genu valgum, Platyspondyly, Shoulder flexion contracture, Pectus carinatum, Scol... ORPHA:800
Osteogenesis Imperfecta, Type Vii
Narrow chest, Vertebral compression fracture, Delayed cranial suture closure, Scoliosis, Pectus e... OMIM:610682
Otopalatodigital Syndrome Type 2
Tarsal synostosis, Narrow chest, Scoliosis, Synostosis of carpal bones, Abnormal rib morphology, ... ORPHA:90652
Trisomy 1Q
Short thorax, Camptodactyly of finger, Abnormal rib morphology ORPHA:261344
Monosomy 9Q22.3
Abnormality of the vertebral column, Pectus excavatum, Kyphosis, Abnormal rib morphology, Short n... ORPHA:77301
Congenital Adrenal Hyperplasia Due To Cytochrome P450 Oxidoreductase Deficiency
Limited elbow extension, Tarsal synostosis, Cubitus valgus, Abnormality of the wrist, Narrow ches... ORPHA:95699
Osteogenesis Imperfecta
Genu valgum, Narrow chest, Enlarged vertebral pedicles, Dislocated radial head, Pectus carinatum,... ORPHA:666
Dextrocardia
Abnormal rib morphology, Congenital hip dislocation ORPHA:1666
Camptodactyly Syndrome, Guadalajara Type 3
Short neck, Spina bifida occulta, Abnormal rib morphology ORPHA:488434
Fibrous Dysplasia Of Bone
Abnormal clavicle morphology, Abnormal lumbar spine morphology, Scoliosis, Abnormal rib morpholog... ORPHA:249
Mucopolysaccharidosis Type 3
Abnormal clavicle morphology, Genu valgum, Abnormal form of the vertebral bodies, Scoliosis, Abno... ORPHA:581
Myhre Syndrome
Platyspondyly, Abnormal rib morphology ORPHA:2588
Simpson-Golabi-Behmel Syndrome
Scoliosis, Vertebral segmentation defect, Pectus excavatum, Abnormal rib morphology, Congenital h... ORPHA:373
Ear-Patella-Short Stature Syndrome
Abnormal rib morphology, Camptodactyly of finger, Patellar aplasia, Craniosynostosis, Elbow dislo... ORPHA:2554
Monosomy 9P
Short neck, Scoliosis, Abnormal rib morphology, Abnormality of the vertebral column ORPHA:261112
Ulbright-Hodes Syndrome
Thin ribs, Short ribs, Abnormal rib morphology, Humeroradial synostosis, Short sternum, Ovoid tho... ORPHA:3404
Vater/Vacterl Association
Abnormal vertebral morphology, Abnormal sternum morphology, Scoliosis, Abnormal rib morphology, R... OMIM:192350
Smith-Lemli-Opitz Syndrome
Abnormal form of the vertebral bodies, Scoliosis, Abnormal rib morphology, Kyphosis, Short neck, ... ORPHA:818
Trisomy 18
Camptodactyly of finger, Abnormal rib morphology ORPHA:3380
Oculocerebrorenal Syndrome Of Lowe
Genu valgum, Platyspondyly, Arthritis, Scoliosis, Abnormal rib morphology, Kyphosis, Joint swelli... ORPHA:534
Hereditary Acrokeratotic Poikiloderma
Camptodactyly of finger, Abnormal rib morphology ORPHA:2907
Pagod Syndrome
Abnormal clavicle morphology, Abnormal rib morphology ORPHA:991
Alagille Syndrome 1
Hemivertebrae, Butterfly vertebral arch, Abnormal rib morphology OMIM:118450
Autosomal Recessive Malignant Osteopetrosis
Craniosynostosis, Narrow chest, Abnormal rib morphology ORPHA:667
Kindler Epidermolysis Bullosa
Camptodactyly of finger, Abnormal rib morphology ORPHA:2908
Charge Syndrome
Scoliosis, Hemivertebrae, Abnormal rib morphology ORPHA:138
Fraser Syndrome
Vertebral segmentation defect, Abnormal rib morphology ORPHA:2052
Charge Syndrome
Scoliosis, Hemivertebrae, Abnormal rib morphology, Radial head subluxation, Down-sloping shoulders OMIM:214800
Townes-Brocks Syndrome
Abnormal vertebral morphology, Abnormal rib morphology ORPHA:857

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Hoxa6

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Hoxa6.

No publications found that use IMPC mice or data for Hoxa6.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

MGI Allele Allele Type Produced
Hoxa6tm87145(L1L2_Bact_P) KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors
Hoxa6tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) ES Cells

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