Gene: Hmgn2

Order

Name high mobility group nucleosomal binding domain 2

Synonyms
  • HMG-17
  • Hmg17

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:96136    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Subviable

Phenotype associations for Hmgn2

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Hmgn2 data for that phenotype.

Embryo Data: 3D Embryo Imaging
Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal embryo size Hmgn2tm1b(KOMP)Wtsi HOM Male embryonic day 15.5 0.0
preweaning lethality, incomplete penetrance Hmgn2tm1b(KOMP)Wtsi HOM Female Male n/a 0.0
increased neutrophil cell number Hmgn2tm1b(KOMP)Wtsi HET Male postnatal 4.33E-9

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415) (1/2)
Aorta 2 No
Brain 2 No (2/2)
Brainstem 2 No (2/2)
Cartilage tissue 2 No
Cerebellum 2 No (2/2)
Cerebral cortex 2 No (2/2)
Esophagus 2 No (7/415)
Eye 2 No (2/2)
Heart 2 No (2/2)
Hippocampus 2 No (2/2)
Hypothalamus 2 No (2/2)
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584)
Liver 2 No
Lower urinary tract 2 No (2/2)
Lung 2 No
Lymph node 2 No
Mammary gland 2 No
Olfactory lobe 2 No (2/2)
Ovary 2 No (1/584) (1/2)
Oviduct 2 No
Pancreas 2 No (5/584) (2/2)
Peripheral nervous system 2 No
Peyer's patch 2 No
Pituitary gland 2 No
Prostate gland 2 No (12/584) (1/2)
Skeletal muscle 2 No
Skin 2 No (2/2)
Small intestine 2 No (9/584)
Spinal cord 2 No (2/2)
Spleen 2 No (2/584) (2/2)
Stomach 2 No (12/584)
Striatum 2 No
Testis 2 No (2/584) (1/2)
Thymus 2 No
Thyroid gland 2 No (15/584) (2/2)
Trachea 2 No (2/2)
Uterus 2 No
Vascular system 2 No (2/2)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse
    respiratory system endocrine system
    cardiovascular system
    nervous system
    sensory organ
    reproductive system
    immune system
    exocrine system
    integumental system
    trunk
    urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2 (1/51) (2/2)
Brain 6 (6/485) (2/7)
Central nervous system ganglion 2 (1/51) (2/2)
Ear 6 (1/485) (2/7)
Embryo 6 (1/485) (2/7)
Eye 6 (1/485) (2/7)
Foot 6 (1/485) (2/7)
Forebrain 6 (1/485) (2/7)
Forelimb 6 (1/485) (2/7)
Gut 2 (1/50) (2/2)
Hand 6 (1/485) (2/7)
Head 6 (5/485) (2/7)
Heart 6 (1/485) (2/7)
Hindbrain 6 (6/485) (2/7)
Hindlimb 6 (1/485) (2/7)
Liver 6 (1/485) (2/7)
Lung 6 (1/485) (2/7)
Mandibular process 6 (1/485) (2/7)
Maxillary process 6 (1/485) (2/7)
Midbrain 6 (1/485) (2/7)
Nose 2 (1/51) (2/2)
Oral cavity 6 (1/485) (2/7)
6 (7/25) (7/7)
Skeleton 2 (1/51) (2/2)
Skin 6 (1/485) (2/7)
Spinal cord 2 (1/50) (2/2)
Tail 6 (1/485) (2/7)
Tail somite 6 (1/485) (2/7)
Trachea 2 (1/50) (2/2)
Urinary system 2 (1/50) (2/2)


Associated Images

Associated Images
  • Embryo LacZ: LacZ images wholemount
    20 Images
  • Adult LacZ: LacZ Images Section
    19 Images
  • X-ray: XRay Images Lateral Orientation
    12 Images
  • X-ray: XRay Images Dorso Ventral
    8 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Hmgn2tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Hmgn2tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Fixed Tissue