Gene: Hbb-bh2

Order

Name hemoglobin beta, bh2

Synonyms Gm5736

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:96025    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Hbb-bh2

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Hbb-bh2 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
decreased mean corpuscular hemoglobin Hbb-bh2tm1b(EUCOMM)Hmgu HOM Female Male postnatal 1.65E-11
increased red blood cell distribution width Hbb-bh2tm1b(EUCOMM)Hmgu HOM Female Male postnatal 9.13E-9

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 4 No (2/415)
Aorta 4 No
Bone 4 Yes
Brain 4 No
Brainstem 4 No
Brown adipose tissue 4 No
Cartilage tissue 4 No
Cecum 4 Yes (12/383)
Cerebellum 4 No
Cerebral cortex 4 No
Chest bone 4 Yes
Colon 4 No (12/127)
Cranium 4 No
Diaphragm 4 Yes
Duodenum 4 Yes (2/127)
Epididymis 4 Yes (18/134)
Esophagus 4 No (7/415)
Eye 4 No
Gall bladder 4 Yes
Gonadal fat pad 4 No
Harderian gland 4 Yes
Heart 4 Yes
Hindlimb 4 No
Hippocampus 4 No
Hypothalamus 4 No
Ileum 4 Yes (14/127)
Jejunum 4 Yes (6/127)
Kidney 4 Yes (18/584)
Large intestine 4 Yes (10/584)
Liver 4 Yes
Lower urinary tract 4 No
Lung 4 Yes
Lymph node 4 Yes
Main olfactory bulb 4 No
Mammary gland 4 No
Mesenteric lymph node 4 Yes
Mesenteric adipose tissue 4 No
Midbrain 4 No
Olfactory lobe 4 No
Oral epithelium 4 No
Ovary 4 Yes (1/584)
Oviduct 4 Yes
Pancreas 4 No (5/584)
Parathyroid gland 4 No
Parotid gland 4 Yes
Penis 4 No
Peripheral nervous system 4 No
Peyer's patch 4 No
Pituitary gland 4 Yes
Prostate gland 4 Yes (12/584)
Quadriceps 4 No
Sciatic nerve 4 No
Skeletal muscle 4 No
Skin 4 Yes
Small intestine 4 No (9/584)
Spinal cord 4 No
Spleen 4 Yes (2/584) (5/6)
Stomach 4 Yes (12/584)
Stomach pyloric region 4 No
Striatum 4 No
Sublingual gland 4 Yes
Submandibular gland 4 Yes (2/132)
Testis 4 Yes (2/584) (3/6)
Thalamus 4 No
Thymus 4 Yes
Thyroid gland 4 Yes (15/584)
Tongue 4 No (5/127)
Trachea 4 No
Trigeminal V nerve 4 No
Urinary bladder 4 Yes
Uterus 4 Yes
Vagina 4 No
Vas deferens 4 No (15/388)
Vascular system 4 No
Vesicular gland 4 Yes
White adipose tissue 4 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse
    reproductive system
    immune system
    trunk
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 1 (6/485)
Ear 1 (1/485)
Embryo 1 (1/485) (4/4)
Eye 1 (1/485)
Foot 1 (1/485) (3/4)
Forearm 1 (1/282)
Forebrain 1 (1/485)
Forelimb 1 (1/485)
Hand 1 (1/485) (3/4)
Head 1 (5/485) (3/4)
Heart 1 (1/485) (4/4)
Hindbrain 1 (6/485)
Hindlimb 1 (1/485)
Liver 1 (1/485) (4/4)
Lower leg 1 (1/282)
Lung 1 (1/485)
Mandibular process 1 (1/485)
Maxillary process 1 (1/485)
Midbrain 1 (1/485)
Oral cavity 1 (1/485)
Skin 1 (1/485)
Tail 1 (1/485)
Tail somite 1 (1/485)
Upper arm 1 (1/282)
Upper leg 1 (1/282)
  • limb(4)
    Footplate expression
    EMAPA:17459 foot


Associated Images

Associated Images
  • Adult LacZ: LacZ Images Wholemount
    143 Images
  • Embryo LacZ: LacZ images wholemount
    66 Images
  • Eye Morphology: Images Ophthalmoscopy
    4 Images
  • X-ray: XRay Images Lateral Orientation
    10 Images
  • X-ray: XRay Images Dorso Ventral
    10 Images
  • Eye Morphology: Images Slit Lamp
    1 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Hbb-bh2tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Hbb-bh2tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Hbb-bh2tm1(KOMP)Mbp Reporter-tagged deletion allele (with selection cassette)
Vector
Gene