Gene: Grin1
Name glutamate receptor, ionotropic, NMDA1 (zeta 1)
Synonyms
- M100174
- NR1
- NMDAR1
- Nmdar
- Rgsc174
- GluRzeta1
Status
ES CellsMice
tm1aphenotype data available
Links MGI:95819 Ensembl Gene Ensembl Orthologs
Viability Homozygous - Lethal
Phenotype associations for Grin1
All Phenotypes Summary
Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Grin1 data for that phenotype.
Embryo Data:
DMDD Images and Phenotypes
Significant Phenotypes
System | Phenotype | Allele | Zyg | Sex | Life Stage | P Value | Data |
---|---|---|---|---|---|---|---|
|
preweaning lethality, complete penetrance | Grin1tm1a(EUCOMM)Wtsi | HOM |
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n/a | 0.0 |
Expression
IMPC lacZ Expression Data
Show expression table
Expression No Expression No Tissue Available Ambiguous
Show Wildtype Expression
Anatomy | #HET Specimens | HOM Images? | WT Expr | Mutant Expr | Images |
---|---|---|---|---|---|
Adrenal gland | 2 | No | |||
Aorta | 2 | No | (1/562) | ||
Blood vessel | 2 | No | |||
Bone | 2 | No | (1/539) | ||
Brain | 2 | No | (5/562) | (2/2) | |
Brainstem | 2 | No | (4/562) | ||
Brown adipose tissue | 2 | No | |||
Cartilage tissue | 2 | No | (1/562) | ||
Cerebellum | 2 | No | (4/562) | ||
Cerebral cortex | 2 | No | (5/562) | ||
Eye | 2 | No | (1/562) | ||
Gall bladder | 2 | No | |||
Heart | 2 | No | (3/562) | ||
Hippocampus | 2 | No | (5/562) | ||
Hypothalamus | 2 | No | (4/562) | ||
Kidney | 2 | No | (19/562) | ||
Large intestine | 2 | No | (12/562) | ||
Liver | 2 | No | |||
Lower urinary tract | 2 | No | (3/562) | ||
Lung | 2 | No | (3/562) | ||
Lymph node | 2 | No | (1/562) | ||
Mammary gland | 2 | No | |||
Esophagus | 2 | No | |||
Olfactory lobe | 2 | No | |||
Ovary | 2 | No | (1/562) | ||
Oviduct | 2 | No | (2/562) | ||
Pancreas | 2 | No | (6/562) | ||
Parathyroid gland | 2 | No | (2/540) | ||
Peripheral nervous system | 2 | No | (3/562) | ||
Peyer's patch | 2 | No | |||
Pituitary gland | 2 | No | (1/562) | ||
Prostate gland | 2 | No | (5/562) | ||
Skeletal muscle tissue | 2 | No | |||
Skin | 2 | No | (1/562) | ||
Small intestine | 2 | No | (11/562) | ||
Spinal cord | 2 | No | (3/562) | ||
Spleen | 2 | No | (4/562) | ||
Stomach | 2 | No | (9/562) | ||
Striatum | 2 | No | (4/562) | ||
Testis | 2 | No | (3/562) | ||
Thymus | 2 | No | |||
Thyroid gland | 2 | No | (16/562) | ||
Trachea | 2 | No | (3/562) | ||
Uterus | 2 | No | (2/562) | ||
White adipose tissue | 2 | No |
Expression in Anatomogram
Tissues/organs lacZ+ expression
postnatal mouse | nervous system |
No expression image was found for this adult tab
No expression data was found for this embryo tab
Secondary lacZ Expression Data
nervous system (2)
Associated Images
Order Mouse and ES Cells
Targeting Detail | Product Ordering | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
MGI Allele | Allele Type | Type Map Seq | Vector | ES Cell | Mouse | Tissue Enquiry | ||||||
Grin1tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) |
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Grin1tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) |
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Grin1tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) |
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