Gene: Bach1

Order

Name BTB and CNC homology 1, basic leucine zipper transcription factor 1

Synonyms 6230421P05Rik

Status ES CellsMice
tm1
Mice
tm1.1
phenotype data available

Links MGI:894680    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Subviable

Phenotype associations for Bach1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Bach1 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
preweaning lethality, incomplete penetrance Bach1tm1.1(KOMP)Vlcg HOM Female Male n/a 0.0
increased fasted circulating glucose level Bach1tm1.1(KOMP)Vlcg HET Female postnatal 4.88E-12
increased circulating sodium level Bach1tm1.1(KOMP)Vlcg HET Female Male postnatal 2.98E-5
increased bone mineral content Bach1tm1.1(KOMP)Vlcg HET Male postnatal 3.47E-5
abnormal sleep behavior Bach1tm1.1(KOMP)Vlcg HET Female Male postnatal 4.79E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415) (2/2)
Aorta 2 No (2/2)
Bone marrow 2 No (2/2)
Brain 2 No (2/2)
Brainstem 2 No (2/2)
Brown adipose tissue 2 No (2/2)
Cartilage tissue 2 No (2/2)
Cerebellum 2 No (2/2)
Cerebral cortex 2 No (2/2)
Epididymis 2 No (18/134) (1/2)
Esophagus 2 No (7/415) (2/2)
Eye 2 No (2/2)
Heart 2 No (2/2)
Hippocampus 2 No (2/2)
Hypothalamus 2 No (2/2)
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584) (2/2)
Liver 2 No (2/2)
Lower urinary tract 2 No
Lung 2 No (2/2)
Lymph node 2 No (2/2)
Mammary gland 2 No
Midbrain 2 No (2/2)
Olfactory lobe 2 No (2/2)
Ovary 2 No (1/584) (1/2)
Oviduct 2 No (1/2)
Pancreas 2 No (5/584) (2/2)
Peripheral nervous system 2 No (2/2)
Peyer's patch 2 No (2/2)
Pituitary gland 2 No (2/2)
Prostate gland 2 No (12/584)
Skeletal muscle 2 No (2/2)
Skin 2 No (2/2)
Small intestine 2 No (9/584) (2/2)
Spinal cord 2 No (2/2)
Spleen 2 No (2/584) (2/2)
Stomach 2 No (12/584) (2/2)
Striatum 2 No (2/2)
Submandibular gland 2 No (2/132) (2/2)
Testis 2 No (2/584) (1/2)
Thalamus 2 No (2/2)
Thymus 2 No (2/2)
Thyroid gland 2 No (15/584) (2/2)
Trachea 2 No (2/2)
Urinary bladder 2 No (2/2)
Uterus 2 No (1/2)
Vascular system 2 No (2/2)
Vesicular gland 2 No
White adipose tissue 2 No (2/2)
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system respiratory system digestive system cardiovascular system set of connective tissues reproductive system musculoskeletal system adipose tissue trunk postnatal mouse nervous system sensory organ immune system exocrine system integumental system urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2 (6/485) (2/3)
Dorsal root ganglion 1 (1/47) Image Only
Ear 2 (1/485) (1/3)
Embryo 2 (1/485) (2/3)
Eye 2 (1/485) (1/3)
Foot 2 (1/485) (2/3)
Forebrain 2 (1/485) (2/3)
Forelimb 2 (1/485) (2/3)
Fronto-nasal process 1 (1/48) Image Only
Hand 2 (1/485) (2/3)
Head 2 (5/485) (2/3)
Heart 2 (1/485) (1/3)
Hindbrain 2 (6/485) (2/3)
Hindlimb 2 (1/485) (2/3)
Liver 2 (1/485) Image Only
Lung 2 (1/485) (1/3)
Mandibular process 2 (1/485) (2/3)
Maxillary process 2 (1/485) (2/3)
Midbrain 2 (1/485) (2/3)
Nose 1 (1/51) (1/1)
Oral cavity 2 (1/485) (1/3)
Skin 2 (1/485) (2/3)
Spinal cord 2 (1/50) (2/2)
Tail 2 (1/485) (2/3)
Tail somite 2 (1/485) (1/3)


Associated Images

Associated Images
  • X-ray: XRay Images Forepaw
    10 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    10 Images
  • Embryo LacZ: LacZ images wholemount
    8 Images
  • X-ray: XRay Images Dorso Ventral
    10 Images
  • Sleep Wake: Wake state (bmp file)
    15 Images
  • X-ray: XRay Images Lateral Orientation
    10 Images
  • X-ray: XRay Images Skull Lateral Orientation
    10 Images
  • Electroretinography: Rod waveform (pdf format)
    3 Images
  • Electroretinography: Cone waveform (pdf format)
    3 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Bach1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene
Bach1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Bach1tm1(NCOM)Cmhd Reporter-tagged deletion allele (with selection cassette)
Vector
Gene
Bach1tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette)
Vector
Gene