Gene: Lin28b
Name lin-28 homolog B (C. elegans)
Synonyms
- D030047M17Rik
- 2810403D23Rik
Status
ES CellsMice
tm1aMice
tm1bphenotype data available
Links MGI:3584032 Ensembl Gene Ensembl Orthologs My Genes
Viability Homozygous - Viable
Phenotype associations for Lin28b
All Phenotypes Summary
Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Lin28b data for that phenotype.
Significant Phenotypes
| System | Phenotype | Allele | Zyg | Sex | Life Stage | P Value | Data |
|---|---|---|---|---|---|---|---|
|
|
shortened RR interval | Lin28btm1b(EUCOMM)Hmgu | HOM |
|
postnatal | 3.27E-5 |
Expression
IMPC lacZ Expression Data
Show expression table
Expression No Expression No Tissue Available Ambiguous
Show Wildtype Expression
| Anatomy | #HET Specimens | HOM Images? | WT Expr | Mutant Expr | Images |
|---|---|---|---|---|---|
| Adrenal gland | 2 | No | (5/393) | ||
| Aorta | 2 | No | (1/562) | ||
| Brain | 2 | No | (6/562) | (2/2) | |
| Brainstem | 2 | No | (4/562) | (2/2) | |
| Brown adipose tissue | 2 | No | |||
| Cartilage tissue | 2 | No | (1/562) | ||
| Cerebellum | 2 | No | (4/562) | (2/2) | |
| Cerebral cortex | 2 | No | (5/562) | (2/2) | |
| Epididymis | 2 | No | (4/106) | ||
| Esophagus | 2 | No | (2/393) | ||
| Eye | 2 | No | (1/562) | (2/2) | |
| Heart | 2 | No | (3/562) | (2/2) | |
| Hippocampus | 2 | No | (5/562) | (2/2) | |
| Hypothalamus | 2 | No | (4/562) | (2/2) | |
| Kidney | 2 | No | (20/562) | (2/2) | |
| Large intestine | 2 | No | (12/562) | ||
| Liver | 2 | No | |||
| Lower urinary tract | 2 | No | (3/562) | ||
| Lung | 2 | No | (3/562) | ||
| Lymph node | 2 | No | (1/562) | ||
| Mammary gland | 2 | No | |||
| Midbrain | 2 | No | (2/2) | ||
| Olfactory lobe | 2 | No | (4/393) | (2/2) | |
| Ovary | 2 | No | (1/562) | (1/2) | |
| Oviduct | 2 | No | (2/562) | ||
| Pancreas | 2 | No | (6/562) | ||
| Peripheral nervous system | 2 | No | (3/562) | ||
| Peyer's patch | 2 | No | (1/393) | ||
| Pituitary gland | 2 | No | (1/562) | (2/2) | |
| Prostate gland | 2 | No | (5/562) | ||
| Skeletal muscle | 2 | No | |||
| Skin | 2 | No | (1/562) | ||
| Small intestine | 2 | No | (11/562) | ||
| Spinal cord | 2 | No | (3/562) | (2/2) | |
| Spleen | 2 | No | (4/562) | ||
| Stomach | 2 | No | (9/562) | ||
| Striatum | 2 | No | (4/562) | (2/2) | |
| Submandibular gland | 2 | No | (1/104) | (1/2) | |
| Testis | 2 | No | (4/562) | (1/2) | |
| Thalamus | 2 | No | (2/2) | ||
| Thymus | 2 | No | |||
| Thyroid gland | 2 | No | (16/562) | ||
| Trachea | 2 | No | (3/562) | ||
| Urinary bladder | 2 | No | |||
| Uterus | 2 | No | (2/562) | ||
| Vascular system | 2 | No | (1/393) | ||
| Vesicular gland | 2 | No | |||
| White adipose tissue | 2 | No |
No expression image was found for this adult tab
Expression No Expression No Tissue Available Ambiguous
| Anatomy | #HET Specimens | WT Expr | Mutant Expr | Images |
|---|---|---|---|---|
| Brain | 2 | (6/482) | (2/3) | |
| Dorsal root ganglion | 1 | (1/45) | ||
| Ear | 2 | (1/482) | (1/3) | |
| Embryo | 2 | (1/482) | (2/3) | |
| Eye | 2 | (1/482) | (2/3) | |
| Foot | 2 | (1/482) | (2/3) | |
| Forebrain | 2 | (1/482) | (2/3) | |
| Forelimb | 2 | (1/482) | (2/3) | |
| Fronto-nasal process | 1 | (1/46) | Image Only | |
| Hand | 2 | (1/482) | (2/3) | |
| Head | 2 | (5/482) | (2/3) | |
| Heart | 2 | (1/482) | (2/3) | |
| Hindbrain | 2 | (6/482) | (2/3) | |
| Hindlimb | 2 | (1/482) | (2/3) | |
| Liver | 2 | (1/482) | ||
| Lung | 2 | (1/482) | ||
| Mandibular process | 2 | (1/482) | (2/3) | |
| Maxillary process | 2 | (1/482) | ||
| Midbrain | 2 | (1/482) | (2/3) | |
| Nose | 1 | (1/47) | (1/1) | |
| Oral cavity | 2 | (1/482) | ||
| Skin | 2 | (1/482) | (1/3) | |
| Spinal cord | 1 | (1/46) | (1/1) | |
| Tail | 2 | (1/482) | (2/3) | |
| Tail somite | 2 | (1/482) | (1/3) |
Associated Images
Associated Images
-
Embryo LacZ: LacZ images wholemount
12 Images
-
X-ray: XRay Images Dorso Ventral
10 Images
-
X-ray: XRay Images Skull Lateral Orientation
10 Images
-
Sleep Wake: Wake state (bmp file)
16 Images
-
X-ray: XRay Images Lateral Orientation
10 Images
-
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
-
X-ray: XRay Images Forepaw
10 Images
-
Combined SHIRPA and Dysmorphology
2 Images
-
Eye Morphology: Images Slit Lamp
1 Images
Order Mouse and ES Cells
| Targeting Detail | Product Ordering | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MGI Allele | Allele Type | Type Map Seq | Vector | ES Cell | Mouse | Tissue Enquiry | ||||||
| Lin28btm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) |
|
||||||||||
| Lin28btm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (post-Cre) |
|
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