Gene: Elmod1

Name ELMO/CED-12 domain containing 1

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:3583900   Ensembl Gene   Ensembl Orthologs

Viability Homozygous - Viable

Phenotype associations for Elmod1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Elmod1 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
increased startle reflex Elmod1tm1a(EUCOMM)Hmgu HOM Female Male postnatal 1.67E-33
decreased body weight Elmod1tm1a(EUCOMM)Hmgu HOM Female Male postnatal 2.98E-26
abnormal behavior Elmod1tm1b(EUCOMM)Hmgu HOM Female Male postnatal 3.61E-22
head bobbing Elmod1tm1b(EUCOMM)Hmgu HOM Female Male postnatal 2.46E-21
abnormal locomotor behavior Elmod1tm1b(EUCOMM)Hmgu HOM Female Male postnatal 7.95E-21
abnormal ear morphology Elmod1tm1b(EUCOMM)Hmgu HOM Female Male postnatal 9.35E-20
abnormal startle reflex Elmod1tm1a(EUCOMM)Hmgu HOM Female Male postnatal 1.98E-19
abnormal behavior Elmod1tm1a(EUCOMM)Hmgu HOM Female Male postnatal 8.22E-19
abnormal gait Elmod1tm1b(EUCOMM)Hmgu HOM Female Male postnatal 1.64E-17
absent startle reflex Elmod1tm1b(EUCOMM)Hmgu HOM Female Male postnatal 1.66E-17
decreased startle reflex Elmod1tm1b(EUCOMM)Hmgu HOM Female Male postnatal 2.39E-17
trunk curl Elmod1tm1b(EUCOMM)Hmgu HOM Female Male postnatal 1.15E-14
decreased total body fat amount Elmod1tm1b(EUCOMM)Hmgu HOM Female Male postnatal 1.17E-13
increased red blood cell distribution width Elmod1tm1b(EUCOMM)Hmgu HOM Female Male postnatal 2.83E-13
decreased grip strength Elmod1tm1b(EUCOMM)Hmgu HOM Female Male postnatal 4.47E-13
increased circulating alkaline phosphatase level Elmod1tm1a(EUCOMM)Hmgu HOM Male postnatal 2.41E-12
increased lean body mass Elmod1tm1b(EUCOMM)Hmgu HOM Female Male postnatal 1.96E-10
impaired pupillary reflex Elmod1tm1a(EUCOMM)Hmgu HOM Female Male postnatal 2.25E-10
abnormal gait Elmod1tm1a(EUCOMM)Hmgu HOM Female Male postnatal 2.85E-10
decreased grip strength Elmod1tm1a(EUCOMM)Hmgu HOM Female Male postnatal 5.12E-10
tremors Elmod1tm1a(EUCOMM)Hmgu HOM Female postnatal 2.28E-9
hyperactivity Elmod1tm1b(EUCOMM)Hmgu HOM Female Male postnatal 3.17E-9
thrombocytopenia Elmod1tm1a(EUCOMM)Hmgu HOM Female Male postnatal 1.43E-8
increased blood urea nitrogen level Elmod1tm1a(EUCOMM)Hmgu HOM Female Male postnatal 4.1E-8
decreased prepulse inhibition Elmod1tm1a(EUCOMM)Hmgu HOM Female Male postnatal 7.58E-8
abnormal locomotor activation Elmod1tm1a(EUCOMM)Hmgu HOM Female Male postnatal 1.22E-7
decreased lymphocyte cell number Elmod1tm1b(EUCOMM)Hmgu HOM Female Male postnatal 1.58E-7
increased mean corpuscular volume Elmod1tm1b(EUCOMM)Hmgu HOM Female Male postnatal 2.12E-7
decreased neutrophil cell number Elmod1tm1b(EUCOMM)Hmgu HOM Male postnatal 4.29E-7
decreased leukocyte cell number Elmod1tm1b(EUCOMM)Hmgu HOM Female Male postnatal 4.47E-7
increased circulating chloride level Elmod1tm1a(EUCOMM)Hmgu HOM Female Male postnatal 4.76E-7
abnormal bone structure Elmod1tm1b(EUCOMM)Hmgu HOM Female postnatal 7.49E-7
increased kidney weight Elmod1tm1b(EUCOMM)Hmgu HOM Male postnatal 1.76E-6
increased or absent threshold for auditory brainstem response Elmod1tm1b(EUCOMM)Hmgu HOM Female Male postnatal 2.0E-6
decreased prepulse inhibition Elmod1tm1b(EUCOMM)Hmgu HOM Female Male postnatal 2.07E-6
decreased leukocyte cell number Elmod1tm1a(EUCOMM)Hmgu HOM Female Male postnatal 3.24E-6
shortened PQ interval Elmod1tm1b(EUCOMM)Hmgu HOM Male postnatal 4.77E-6
abnormal response to tactile stimuli Elmod1tm1a(EUCOMM)Hmgu HOM Female Male postnatal 5.98E-6
increased blood urea nitrogen level Elmod1tm1b(EUCOMM)Hmgu HOM Female postnatal 9.52E-6
thrombocytopenia Elmod1tm1b(EUCOMM)Hmgu HOM Male postnatal 9.61E-6
shortened PR interval Elmod1tm1b(EUCOMM)Hmgu HOM Male postnatal 1.07E-5
decreased circulating triglyceride level Elmod1tm1b(EUCOMM)Hmgu HOM Male postnatal 1.17E-5
increased circulating triglyceride level Elmod1tm1b(EUCOMM)Hmgu HOM Female postnatal 1.17E-5
increased mean corpuscular hemoglobin Elmod1tm1b(EUCOMM)Hmgu HOM Female Male postnatal 1.69E-5
decreased hemoglobin content Elmod1tm1a(EUCOMM)Hmgu HOM Male postnatal 6.94E-5
increased hemoglobin content Elmod1tm1a(EUCOMM)Hmgu HOM Female postnatal 6.94E-5
mammalian phenotype Elmod1tm1a(EUCOMM)Hmgu HOM Male postnatal 8.52E-5
increased heart weight Elmod1tm1b(EUCOMM)Hmgu HOM Female Male postnatal 8.92E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/354)
Aorta 2 No (2/530)
Bone 2 No (1/515)
Brain 2 No (8/530) (2/2)
Brainstem 2 No (5/530)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/530)
Cerebellum 2 No (6/530)
Cerebral cortex 2 No (6/530) (2/2)
Esophagus 2 No (1/354)
Eye 2 No (1/530)
Gall bladder 2 No
Heart 2 No (4/530)
Hippocampus 2 No (7/530) (2/2)
Hypothalamus 2 No (5/529) (2/2)
Kidney 2 No (13/530)
Large intestine 2 No (7/530)
Liver 2 No
Lower urinary tract 2 No (3/530)
Lung 2 No (4/530)
Lymph node 2 No (2/530)
Mammary gland 2 No
Olfactory lobe 2 No (3/354) (2/2)
Oral epithelium 2 No
Ovary 2 No (1/530)
Oviduct 2 No (1/530) (1/2)
Pancreas 2 No (2/530)
Parathyroid gland 2 No (2/516)
Peripheral nervous system 2 No (4/530)
Peyer's patch 2 No (1/354)
Pituitary gland 2 No (2/530) (2/2)
Prostate gland 2 No (3/530)
Skeletal muscle 2 No
Skin 2 No (2/530) (2/2)
Small intestine 2 No (5/530)
Spinal cord 2 No (5/530) (2/2)
Spleen 2 No (3/530)
Stomach 2 No (5/530)
Striatum 2 No (6/530) (2/2)
Testis 2 No (7/530) (1/2)
Thymus 2 No (1/530)
Thyroid gland 2 No (11/530)
Trachea 2 No (5/530)
Uterus 2 No (1/530)
Vascular system 2 No (1/354)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse
    nervous system
    reproductive system
    integumental system
    trunk
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2 (5/413) (3/4)
Ear 2
Embryo 2 (3/4)
Eye 2
Foot 2
Forebrain 2 (3/4)
Forelimb 2
Hand 2
Head 2 (4/413) (2/4)
Heart 2
Hindbrain 2 (5/413)
Hindlimb 2
Liver 2
Lung 2
Mandibular process 2
Maxillary process 2
Midbrain 2
Oral cavity 2
Skin 2
Tail 2
Tail somite 2


Associated Images

Associated Images
  • X-ray: XRay Images Dorso Ventral
    17 Images
  • X-ray: XRay Images Hind Leg and Hip
    8 Images
  • Adult LacZ: LacZ Images Wholemount
    6 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    17 Images
  • X-ray: XRay Images Lateral Orientation
    17 Images
  • Echo: M-Mode Images
    17 Images
  • Embryo LacZ: LacZ images wholemount
    8 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse
Elmod1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Elmod1tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre)
Vector
Gene