Gene: Eme1

Order

Name essential meiotic structure-specific endonuclease 1

Status ES CellsMice
tm1
Mice
tm1.1
phenotype data available

Links MGI:3576783    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Eme1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Eme1 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal spleen morphology Eme1tm1.1(KOMP)Wtsi HOM Male postnatal 0.0
increased erythrocyte cell number Eme1tm1.1(KOMP)Wtsi HOM Female Male postnatal 8.85E-10
increased hemoglobin content Eme1tm1.1(KOMP)Wtsi HOM Female Male postnatal 8.63E-7
increased hematocrit Eme1tm1.1(KOMP)Wtsi HOM Female Male postnatal 6.32E-6
decreased mean corpuscular hemoglobin Eme1tm1.1(KOMP)Wtsi HOM Female Male postnatal 1.35E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (5/393)
Aorta 2 No (1/562)
Bone 2 No (1/539)
Brain 2 No (6/562)
Brainstem 2 No (4/562)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/562)
Cecum 2 No (1/355)
Cerebellum 2 No (4/562)
Cerebral cortex 2 No (5/562)
Esophagus 2 No (2/393)
Eye 2 No (1/562)
Gall bladder 2 No
Heart 2 No (3/562)
Hippocampus 2 No (5/562)
Hypothalamus 2 No (4/562)
Kidney 2 No (20/562)
Large intestine 2 No (12/562)
Liver 2 No
Lower urinary tract 2 No (3/562)
Lung 2 No (3/562)
Lymph node 2 No (1/562)
Mammary gland 2 No
Olfactory lobe 2 No (4/393)
Oral epithelium 2 No
Ovary 2 No (1/562)
Oviduct 2 No (2/562)
Pancreas 2 No (6/562)
Parathyroid gland 2 No (2/540)
Peripheral nervous system 2 No (3/562)
Peyer's patch 2 No (1/393)
Pituitary gland 2 No (1/562)
Prostate gland 2 No (5/562)
Skeletal muscle 2 No
Skin 2 No (1/562)
Small intestine 2 No (11/562)
Spinal cord 2 No (3/562)
Spleen 2 No (4/562)
Stomach 2 No (9/562)
Striatum 2 No (4/562)
Testis 2 No (4/562) (1/2)
Thymus 2 No
Thyroid gland 2 No (16/562)
Trachea 2 No (3/562)
Trigeminal V nerve 2 No
Uterus 2 No (2/562)
Vas deferens 2 No (1/360) (1/2)
Vascular system 2 No (1/393)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse reproductive system trunk
No expression image was found for this adult tab
No expression data was found for this embryo tab


Associated Images

Associated Images
  • X-ray: XRay Images Dorso Ventral
    10 Images
  • X-ray: XRay Images Lateral Orientation
    10 Images
  • X-ray: XRay Images Forepaw
    8 Images
  • X-ray: XRay Images Skull Lateral Orientation
    8 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    8 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Eme1tm1(KOMP)Wtsi Reporter-tagged deletion allele (with selection cassette)
Vector
Gene
Eme1tm1.1(KOMP)Wtsi Reporter-tagged deletion allele (post Cre, with no selection cassette)
Vector
Gene
Eme1tm431825(L1L2_Bact_P)
Vector
Gene