Gene: Pdzd8
Name PDZ domain containing 8
Synonyms
- Pdzk8
- A630041P07Rik
Status
ES CellsMice
tm1aMice
tm1bphenotype data available
Links MGI:2677270 Ensembl Gene Ensembl Orthologs My Genes
Viability Homozygous - Viable
Phenotype associations for Pdzd8
All Phenotypes Summary
Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Pdzd8 data for that phenotype.
Significant Phenotypes
| System | Phenotype | Allele | Zyg | Sex | Life Stage | P Value | Data |
|---|---|---|---|---|---|---|---|
|
|
increased red blood cell distribution width | Pdzd8tm1b(EUCOMM)Wtsi | HOM |
|
postnatal | 7.04E-12 | |
|
|
increased large unstained cell number | Pdzd8tm1b(EUCOMM)Wtsi | HET |
|
postnatal | 7.17E-7 | |
|
|
hyperactivity | Pdzd8tm1b(EUCOMM)Wtsi | HOM |
|
postnatal | 6.37E-6 | |
|
|
decreased circulating alkaline phosphatase level | Pdzd8tm1b(EUCOMM)Wtsi | HET |
|
postnatal | 1.71E-5 | |
|
|
abnormal vibrissa morphology | Pdzd8tm1b(EUCOMM)Wtsi | HOM |
|
postnatal | 2.39E-5 | |
|
|
abnormal behavior | Pdzd8tm1b(EUCOMM)Wtsi | HOM |
|
postnatal | 3.13E-5 | |
|
|
increased circulating phosphate level | Pdzd8tm1b(EUCOMM)Wtsi | HOM |
|
postnatal | 6.29E-5 |
Expression
IMPC lacZ Expression Data
Show expression table
Expression No Expression No Tissue Available Ambiguous
Show Wildtype Expression
| Anatomy | #HET Specimens | HOM Images? | WT Expr | Mutant Expr | Images |
|---|---|---|---|---|---|
| Adrenal gland | 2 | No | (2/415) | (2/2) | |
| Aorta | 2 | No | (2/2) | ||
| Bone | 2 | No | |||
| Brain | 2 | No | (2/2) | ||
| Brainstem | 2 | No | (2/2) | ||
| Brown adipose tissue | 2 | No | |||
| Cartilage tissue | 2 | No | (2/2) | ||
| Cerebellum | 2 | No | (2/2) | ||
| Cerebral cortex | 2 | No | (2/2) | ||
| Esophagus | 2 | No | (7/415) | (2/2) | |
| Eye | 2 | No | |||
| Gall bladder | 2 | No | (2/2) | ||
| Heart | 2 | No | (2/2) | ||
| Hippocampus | 2 | No | (2/2) | ||
| Hypothalamus | 2 | No | (2/2) | ||
| Kidney | 2 | No | (18/584) | (2/2) | |
| Large intestine | 2 | No | (10/584) | (2/2) | |
| Liver | 2 | No | (2/2) | ||
| Lower urinary tract | 2 | No | (2/2) | ||
| Lung | 2 | No | (2/2) | ||
| Lymph node | 2 | No | (2/2) | ||
| Mammary gland | 2 | No | |||
| Olfactory lobe | 2 | No | (2/2) | ||
| Oral epithelium | 2 | No | |||
| Ovary | 2 | No | (1/584) | (1/2) | |
| Oviduct | 2 | No | (1/2) | ||
| Pancreas | 2 | No | (5/584) | (2/2) | |
| Parathyroid gland | 2 | No | (2/2) | ||
| Peripheral nervous system | 2 | No | (2/2) | ||
| Peyer's patch | 2 | No | (2/2) | ||
| Pituitary gland | 2 | No | (2/2) | ||
| Prostate gland | 2 | No | (12/584) | (1/2) | |
| Skeletal muscle | 2 | No | |||
| Skin | 2 | No | (2/2) | ||
| Small intestine | 2 | No | (9/584) | (2/2) | |
| Spinal cord | 2 | No | (2/2) | ||
| Spleen | 2 | No | (2/584) | ||
| Stomach | 2 | No | (12/584) | (2/2) | |
| Striatum | 2 | No | (2/2) | ||
| Testis | 2 | No | (2/584) | (1/2) | |
| Thymus | 2 | No | (2/2) | ||
| Thyroid gland | 2 | No | (15/584) | ||
| Trachea | 2 | No | (2/2) | ||
| Uterus | 2 | No | (1/2) | ||
| Vascular system | 2 | No | (2/2) | ||
| White adipose tissue | 2 | No |
No expression image was found for this adult tab
No expression data was found for this embryo tab
Associated Images
Associated Images
-
X-ray: XRay Images Dorso Ventral
18 Images
-
X-ray: XRay Images Lateral Orientation
18 Images
-
X-ray: XRay Images Skull Dorso Ventral Orientation
18 Images
-
Anti-nuclear antibody assay
1 Images
-
Adult LacZ: LacZ Images Wholemount
23 Images
Order Mouse and ES Cells
| Targeting Detail | Product Ordering | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MGI Allele | Allele Type | Type Map Seq | Vector | ES Cell | Mouse | Tissue Enquiry | ||||||
| Pdzd8tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) |
|
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| Pdzd8tm1b(EUCOMM)Wtsi | Reporter-tagged deletion allele (post-Cre) |
|
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