Gene: Fbxl16

Order

Name F-box and leucine-rich repeat protein 16

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:2448488    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Subviable

Phenotype associations for Fbxl16

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Fbxl16 data for that phenotype.

Embryo Data: 3D Embryo Imaging
Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
prenatal lethality Fbxl16tm1b(KOMP)Wtsi HOM Female Male embryonic day 18.5 0.0
preweaning lethality, incomplete penetrance Fbxl16tm1b(KOMP)Wtsi HOM Female Male n/a 0.0
increased heart rate variability Fbxl16tm1b(KOMP)Wtsi HET Female Male postnatal 4.26E-5
cardiovascular system phenotype Fbxl16tm1b(KOMP)Wtsi HET Female Male postnatal 5.36E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415) (2/2)
Aorta 2 No
Bone 2 No
Brain 2 No (2/2)
Brainstem 2 No (2/2)
Brown adipose tissue 2 No
Cartilage tissue 2 No
Cecum 2 No (12/383)
Cerebellum 2 No (2/2)
Cerebral cortex 2 No (2/2)
Esophagus 2 No (7/415)
Eye 2 No
Gall bladder 2 No
Heart 2 No
Hippocampus 2 No (2/2)
Hypothalamus 2 No (2/2)
Kidney 2 No (18/584)
Large intestine 2 No (10/584) (2/2)
Liver 2 No
Lower urinary tract 2 No
Lung 2 No
Lymph node 2 No (2/2)
Mammary gland 2 No
Olfactory lobe 2 No (2/2)
Oral epithelium 2 No
Ovary 2 No (1/584)
Oviduct 2 No
Pancreas 2 No (5/584)
Parathyroid gland 2 No
Peripheral nervous system 2 No (2/2)
Peyer's patch 2 No
Pituitary gland 2 No (1/2)
Prostate gland 2 No (12/584)
Skeletal muscle 2 No
Skin 2 No
Small intestine 2 No (9/584) (2/2)
Spinal cord 2 No (2/2)
Spleen 2 No (2/584)
Stomach 2 No (12/584)
Striatum 2 No (2/2)
Testis 2 No (2/584) (1/2)
Thymus 2 No
Thyroid gland 2 No (15/584) (2/2)
Trachea 2 No
Trigeminal V nerve 2 No (2/2)
Uterus 2 No
Vas deferens 2 No (15/388) (1/2)
Vascular system 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system
    postnatal mouse
    digestive system
    nervous system
    reproductive system
    immune system
    trunk
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Heart atrium 4 (1/47)
Axial skeleton 4 (1/51)
Brain 4 (6/485) (4/4)
Central nervous system ganglion 4 (1/51)
Cranium 4 (1/46) (4/4)
Dorsal root ganglion 4 (1/47) (4/4)
Ear 4 (1/485)
Embryo 4 (1/485) (4/4)
Outer ear 4 (1/47)
Eye 4 (1/485) (4/4)
Femur pre-cartilage condensation 4 (1/46)
Foot 4 (1/485)
Forearm 4 (1/282)
Forebrain 4 (1/485) (4/4)
Forelimb 4 (1/485)
Fronto-nasal process 4 (1/48) (4/4)
Gut 4 (1/50)
Hand 4 (1/485)
Head 4 (5/485) (4/4)
Head mesenchyme 4 (1/47)
Heart 4 (1/485)
Heart ventricle 4 (1/47)
Hindbrain 4 (6/485) (4/4)
Hindlimb 4 (1/485)
Humerus pre-cartilage condensation 4 (1/46)
Inner ear 4 (1/46)
Intestine 4 (1/47)
Liver 4 (1/485)
Lower leg 4 (1/282)
Lung 4 (1/485)
Mandibular process 4 (1/485)
Maxillary process 4 (1/485)
Mesonephros of female 4 (1/46)
Mesonephros of male 4 (1/46)
Metanephros 4 (1/46)
Midbrain 4 (1/485) (4/4)
Nasal septum 4 (1/47)
Nose 4 (1/51)
Notochord 4 (1/47)
Oral cavity 4 (1/485)
Outflow tract 4 (1/47)
Pancreas 4 (1/46)
Pericardium 4 (1/46)
Pharynx 4 (1/46)
Radius-ulna pre-cartilage condensation 4 (1/46)
Rib pre-cartilage condensation 4 (1/46)
Skeleton 4 (1/51)
Skin 4 (1/485)
Spinal cord 4 (1/50) (4/4)
Stomach 4 (1/46)
Tail 4 (1/485)
Tail somite 4 (1/485)
Thoracic vertebral cartilage condensation 4 (1/46)
Tongue 4 (1/46)
Trachea 4 (1/50)
Trunk mesenchyme 4 (1/47)
Umbilical artery embryonic part 4 (1/47)
Umbilical vein embryonic part 4 (1/47)
Upper arm 4 (1/282)
Upper leg 4 (1/282)
Urinary system 4 (1/50)
Vibrissa 4 (1/47)


Associated Images

Associated Images
  • Adult LacZ: LacZ Images Wholemount
    11 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Fbxl16tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Fbxl16tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Fbxl16tm119151(L1L2_Pgk_P)
Vector
Gene