Gene: Marveld2

Name MARVEL (membrane-associating) domain containing 2

Synonyms
  • Tric-a
  • Tric-c
  • Mrvldc2
  • Tricellulin
  • Tric
  • Tric-b

Status ES CellsMice
tm1b
Mice
tm1a
phenotype data available

Links MGI:2446166   Ensembl Gene   Ensembl Orthologs

Viability Homozygous - Viable

Phenotype associations for Marveld2

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Marveld2 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
enlarged heart Marveld2tm1b(EUCOMM)Wtsi HOM Male postnatal 0.0
decreased startle reflex Marveld2tm1b(EUCOMM)Wtsi HOM Female Male postnatal 6.55E-21
absent startle reflex Marveld2tm1b(EUCOMM)Wtsi HOM Female Male postnatal 1.06E-15
abnormal ear morphology Marveld2tm1b(EUCOMM)Wtsi HOM Female Male postnatal 2.95E-15
increased or absent threshold for auditory brainstem response Marveld2tm1b(EUCOMM)Wtsi HOM Female Male postnatal 2.0E-6
decreased prepulse inhibition Marveld2tm1b(EUCOMM)Wtsi HOM Female Male postnatal 5.62E-6

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/354) (1/2)
Aorta 2 No (2/530)
Bone 2 No (1/515)
Brain 2 No (8/530) (2/2)
Brainstem 2 No (5/530) (2/2)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/530)
Cerebellum 2 No (6/530) (2/2)
Cerebral cortex 2 No (6/530) (1/2)
Esophagus 2 No (1/354) (2/2)
Eye 2 No (1/530) (1/2)
Gall bladder 2 No (1/2)
Heart 2 No (4/530)
Hippocampus 2 No (7/530) (1/2)
Hypothalamus 2 No (5/529) (2/2)
Kidney 2 No (13/530) (2/2)
Large intestine 2 No (7/530) (2/2)
Liver 2 No
Lower urinary tract 2 No (3/530) (2/2)
Lung 2 No (4/530) (2/2)
Lymph node 2 No (2/530) (2/2)
Mammary gland 2 No
Olfactory lobe 2 No (3/354) (1/2)
Oral epithelium 2 No (1/2)
Ovary 2 No (1/530) (1/2)
Oviduct 2 No (1/530) (1/2)
Pancreas 2 No (2/530) (2/2)
Parathyroid gland 2 No (2/516) (2/2)
Peripheral nervous system 2 No (4/530) (1/2)
Peyer's patch 2 No (1/354) (2/2)
Pituitary gland 2 No (2/530) (2/2)
Prostate gland 2 No (3/530) (1/2)
Skeletal muscle 2 No
Skin 2 No (2/530) (2/2)
Small intestine 2 No (5/530) (2/2)
Spinal cord 2 No (5/530) (1/2)
Spleen 2 No (3/530)
Stomach 2 No (5/530) (2/2)
Striatum 2 No (6/530)
Testis 2 No (7/530) (1/2)
Thymus 2 No (1/530) (2/2)
Thyroid gland 2 No (11/530) (2/2)
Trachea 2 No (5/530)
Uterus 2 No (1/530)
Vascular system 2 No (1/354)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse
    endocrine system
    respiratory system
    digestive system
    nervous system
    sensory organ
    reproductive system
    immune system
    exocrine system
    integumental system
    trunk
    urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2 (5/413)
Ear 2 (1/4)
Embryo 2 (3/4)
Eye 2 (1/4)
Foot 2 (3/4)
Forebrain 2
Forelimb 2
Hand 2 (3/4)
Head 2 (4/413) (3/4)
Heart 2
Hindbrain 2 (5/413)
Hindlimb 2
Liver 2
Lung 2
Mandibular process 2
Maxillary process 2
Midbrain 2
Oral cavity 2 (1/4)
Skin 2 (3/4)
Tail 2 (2/4)
Tail somite 2


Associated Images

Associated Images
  • X-ray: XRay Images Lateral Orientation
    11 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    10 Images
  • Echo: M-Mode Images
    28 Images
  • Adult LacZ: LacZ Images Wholemount
    22 Images
  • X-ray: XRay Images Dorso Ventral
    10 Images
  • Embryo LacZ: LacZ images wholemount
    8 Images

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse
Marveld2tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Marveld2tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene