Gene: Ppfia2

Order

Name protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

Synonyms
  • E130120L08Rik
  • Liprin-alpha2

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:2443834    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Ppfia2

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Ppfia2 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal gait Ppfia2tm1b(EUCOMM)Hmgu HOM Female postnatal 1.17E-7
head bobbing Ppfia2tm1b(EUCOMM)Hmgu HOM Male postnatal 5.6E-7

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415) (2/2)
Aorta 2 No
Bone 2 No
Brain 2 No (2/2)
Brainstem 2 No
Brown adipose tissue 2 No
Cartilage tissue 2 No
Cerebellum 2 No
Cerebral cortex 2 No (2/2)
Esophagus 2 No (7/415)
Eye 2 No
Gall bladder 2 No
Heart 2 No
Hippocampus 2 No (2/2)
Hypothalamus 2 No (2/2)
Kidney 2 No (18/584)
Large intestine 2 No (10/584)
Liver 2 No
Lower urinary tract 2 No
Lung 2 No
Lymph node 2 No (1/2)
Mammary gland 2 No
Olfactory lobe 2 No (2/2)
Oral epithelium 2 No
Ovary 2 No (1/584)
Oviduct 2 No
Pancreas 2 No (5/584) (1/2)
Parathyroid gland 2 No
Peripheral nervous system 2 No
Peyer's patch 2 No
Pituitary gland 2 No (1/2)
Prostate gland 2 No (12/584)
Skeletal muscle 2 No
Skin 2 No
Small intestine 2 No (9/584)
Spinal cord 2 No
Spleen 2 No (2/584)
Stomach 2 No (12/584)
Striatum 2 No
Testis 2 No (2/584) (1/2)
Thymus 2 No
Thyroid gland 2 No (15/584)
Trachea 2 No
Uterus 2 No
Vascular system 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system
    postnatal mouse
    nervous system
    reproductive system
    immune system
    trunk
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 1 (6/485) (1/2)
Ear 1 (1/485)
Embryo 1 (1/485) (2/2)
Eye 1 (1/485)
Foot 1 (1/485)
Forebrain 1 (1/485) (1/2)
Forelimb 1 (1/485)
Hand 1 (1/485)
Head 1 (5/485) (2/2)
Heart 1 (1/485) Image Only
Hindbrain 1 (6/485)
Hindlimb 1 (1/485)
Liver 1 (1/485)
Lung 1 (1/485)
Mandibular process 1 (1/485)
Maxillary process 1 (1/485)
Midbrain 1 (1/485) (1/2)
Oral cavity 1 (1/485)
Skin 1 (1/485)
Tail 1 (1/485)
Tail somite 1 (1/485)


Associated Images

Associated Images
  • X-ray: XRay Images Lateral Orientation
    9 Images
  • Adult LacZ: LacZ Images Wholemount
    8 Images
  • Echo: M-Mode Images
    32 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    9 Images
  • X-ray: XRay Images Dorso Ventral
    9 Images
  • Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
    6 Images
  • Embryo LacZ: LacZ images wholemount
    8 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Ppfia2tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Ppfia2tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre)
Vector
Gene