Gene: Arhgap25

Order

Name Rho GTPase activating protein 25

Synonyms A130039I20Rik

Status ES CellsMice
tm1a
phenotype data available

Links MGI:2443687    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Arhgap25

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Arhgap25 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
increased effector memory CD4-positive, alpha-beta T cell number Arhgap25tm1a(KOMP)Wtsi HOM Female Male postnatal 1.88E-7
abnormal retina morphology Arhgap25tm1a(KOMP)Wtsi HOM Male postnatal 4.3E-6
abnormal retinal pigmentation Arhgap25tm1a(KOMP)Wtsi HOM Male postnatal 4.3E-6
increased mean corpuscular hemoglobin Arhgap25tm1a(KOMP)Wtsi HOM Female Male postnatal 9.78E-6
increased effector memory CD8-positive, alpha-beta T cell number Arhgap25tm1a(KOMP)Wtsi HOM Female Male postnatal 9.18E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No
Aorta 2 No (1/562)
Blood vessel 2 No
Bone 2 No (1/539)
Brain 2 No (6/562) (1/2)
Brainstem 2 No (4/562)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/562)
Cerebellum 2 No (4/562)
Cerebral cortex 2 No (5/562)
Eye 2 No (1/562) (2/2)
Gall bladder 2 No
Heart 2 No (3/562)
Hippocampus 2 No (5/562)
Hypothalamus 2 No (4/562)
Kidney 2 No (20/562) (1/2)
Large intestine 2 No (12/562)
Liver 2 No
Lower urinary tract 2 No (3/562)
Lung 2 No (3/562)
Lymph node 2 No (1/562) (2/2)
Mammary gland 2 No
Esophagus 2 No (1/2)
Olfactory lobe 2 No
Ovary 2 No (1/562)
Oviduct 2 No (2/562)
Pancreas 2 No (6/562)
Parathyroid gland 2 No (2/540)
Peripheral nervous system 2 No (3/562) (2/2)
Peyer's patch 2 No (2/2)
Pituitary gland 2 No (1/562)
Prostate gland 2 No (5/562)
Skeletal muscle tissue 2 No
Skin 2 No (1/562)
Small intestine 2 No (11/562)
Spinal cord 2 No (3/562)
Spleen 2 No (4/562) (2/2)
Stomach 2 No (9/562)
Striatum 2 No (4/562)
Testis 2 No (4/562) (1/2)
Thymus 2 No
Thyroid gland 2 No (16/562)
Trachea 2 No (3/562)
Uterus 2 No (2/562)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse digestive system nervous system sensory organ reproductive system immune system trunk urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Secondary lacZ Expression Data
postnatal mouse (13)
  • Arhgap25tm1a(KOMP)Wtsi
    bone, HET, Male, WTSI
  • Arhgap25tm1a(KOMP)Wtsi
    spleen, HET, Male, WTSI
  • Arhgap25tm1a(KOMP)Wtsi
    thymus, HET, Male, WTSI
  • Arhgap25tm1a(KOMP)Wtsi
    kidney, HET, Male, WTSI
  • Arhgap25tm1a(KOMP)Wtsi
    ovary, HET, Female, WTSI

show all 13 images

trunk (6)
  • Arhgap25tm1a(KOMP)Wtsi
    spleen, HET, Male, WTSI
  • Arhgap25tm1a(KOMP)Wtsi
    thymus, HET, Male, WTSI
  • Arhgap25tm1a(KOMP)Wtsi
    kidney, HET, Male, WTSI
  • Arhgap25tm1a(KOMP)Wtsi
    ovary, HET, Female, WTSI
  • Arhgap25tm1a(KOMP)Wtsi
    peyer's patch, HET, Male, WTSI

show all 6 images

immune system (4)
  • Arhgap25tm1a(KOMP)Wtsi
    spleen, HET, Male, WTSI
  • Arhgap25tm1a(KOMP)Wtsi
    thymus, HET, Male, WTSI
  • Arhgap25tm1a(KOMP)Wtsi
    peyer's patch, HET, Male, WTSI
  • Arhgap25tm1a(KOMP)Wtsi
    lymph node, HET, Male, WTSI
nervous system (2)
  • Arhgap25tm1a(KOMP)Wtsi
    brain, HET, Male, WTSI
  • Arhgap25tm1a(KOMP)Wtsi
    peripheral nervous system, HET, Male, WTSI
reproductive system (2)
  • Arhgap25tm1a(KOMP)Wtsi
    ovary, HET, Female, WTSI
  • Arhgap25tm1a(KOMP)Wtsi
    testis, HET, Male, WTSI
digestive system (1)
  • Arhgap25tm1a(KOMP)Wtsi
    peyer's patch, HET, Male, WTSI
endocrine system (1)
  • Arhgap25tm1a(KOMP)Wtsi
    thyroid gland, HET, Male, WTSI
integumental system (1)
  • Arhgap25tm1a(KOMP)Wtsi
    tail skin, skin, HET, Male, WTSI
musculoskeletal system (1)
  • Arhgap25tm1a(KOMP)Wtsi
    bone, HET, Male, WTSI
sensory organ (1)
  • Arhgap25tm1a(KOMP)Wtsi
    eye, HET, Male, WTSI
urinary system (1)
  • Arhgap25tm1a(KOMP)Wtsi
    kidney, HET, Male, WTSI

Associated Images

Legacy Phenotype Associated Images
Xray (89)
  • Arhgap25tm1a(KOMP)Wtsi
    body, HOM, Male, WTSI
  • Arhgap25tm1a(KOMP)Wtsi
    forearm, HOM, Female, WTSI
  • Arhgap25tm1a(KOMP)Wtsi
    head, HOM, Male, WTSI
  • Arhgap25tm1a(KOMP)Wtsi
    head, HOM, Female, WTSI
  • Arhgap25tm1a(KOMP)Wtsi
    body, HOM, Female, WTSI

show all 89 images

Eye Morphology (13)
  • Arhgap25tm1a(KOMP)Wtsi
    eye, abnormal retinal pigmentation, HOM, Female, WTSI
  • Arhgap25tm1a(KOMP)Wtsi
    eye, abnormal retinal pigmentation, HOM, Female, WTSI
  • Arhgap25tm1a(KOMP)Wtsi
    eye, abnormal retinal pigmentation, HOM, Female, WTSI
  • Arhgap25tm1a(KOMP)Wtsi
    abnormal retinal pigmentation, left eye, HOM, Male, WTSI
  • Arhgap25tm1a(KOMP)Wtsi
    abnormal retinal pigmentation, right eye, HOM, Male, WTSI

show all 13 images

Skin Histopathology (1)
  • Arhgap25tm1a(KOMP)Wtsi
    back skin, HOM, Female, WTSI

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Arhgap25tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Arhgap25tm2a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Arhgap25tm41908(L1L2_Pgk_PM)
Vector
Gene