Gene: Pxylp1

Name 2-phosphoxylose phosphatase 1

Synonyms
  • C130099A20Rik
  • Acpl2
  • 9430094M07Rik

Status ES CellsMice
tm1a
phenotype data available

Links MGI:2442444   Ensembl Gene   Ensembl Orthologs

Viability Homozygous - Viable

Phenotype associations for Pxylp1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Pxylp1 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
decreased bone mineral density Pxylp1tm1a(KOMP)Wtsi HOM Female Male postnatal 6.19E-7
decreased lean body mass Pxylp1tm1a(KOMP)Wtsi HOM Male postnatal 1.16E-6
decreased bone mineral content Pxylp1tm1a(KOMP)Wtsi HOM Male postnatal 4.51E-6
decreased body weight Pxylp1tm1a(KOMP)Wtsi HOM Male postnatal 4.92E-6
increased body weight Pxylp1tm1a(KOMP)Wtsi HOM Female postnatal 4.92E-6
decreased body length Pxylp1tm1a(KOMP)Wtsi HOM Male postnatal 4.34E-5
decreased mean corpuscular hemoglobin Pxylp1tm1a(KOMP)Wtsi HOM Male postnatal 4.55E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No
Aorta 2 No (1/562)
Blood vessel 2 No
Bone 2 No (1/539)
Brain 2 No (5/562)
Brainstem 2 No (4/562)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/562)
Cerebellum 2 No (4/562)
Cerebral cortex 2 No (5/562)
Eye 2 No (1/562)
Gall bladder 2 No
Heart 2 No (3/562)
Hippocampus 2 No (5/562)
Hypothalamus 2 No (4/562)
Kidney 2 No (19/562)
Large intestine 2 No (12/562) (2/2)
Liver 2 No
Lower urinary tract 2 No (3/562)
Lung 2 No (3/562)
Lymph node 2 No (1/562)
Mammary gland 2 No
Esophagus 2 No
Olfactory lobe 2 No
Ovary 2 No (1/562)
Oviduct 2 No (2/562)
Pancreas 2 No (6/562)
Parathyroid gland 2 No (2/540)
Peripheral nervous system 2 No (3/562)
Peyer's patch 2 No
Pituitary gland 2 No (1/562)
Prostate gland 2 No (5/562) (1/2)
Skeletal muscle tissue 2 No
Skin 2 No (1/562)
Small intestine 2 No (11/562) (2/2)
Spinal cord 2 No (3/562)
Spleen 2 No (4/562)
Stomach 2 No (9/562)
Striatum 2 No (4/562)
Testis 2 No (3/562) (1/2)
Thymus 2 No
Thyroid gland 2 No (16/562)
Trachea 2 No (3/562)
Uterus 2 No (2/562)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse digestive system reproductive system exocrine system trunk
No expression image was found for this adult tab
No expression data was found for this embryo tab


Associated Images

Phenotype associated images not available

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Pxylp1tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Pxylp1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene