Gene: Arhgef11

Order

Name Rho guanine nucleotide exchange factor (GEF) 11

Synonyms
  • PDZ-RhoGEF
  • Prg

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:2441869    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Arhgef11

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Arhgef11 data for that phenotype.

No results meet the p-value threshold


Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415) (2/2)
Aorta 2 No (2/2)
Bone 2 No (2/2)
Brain 2 No (2/2)
Brainstem 2 No (2/2)
Brown adipose tissue 2 No
Cartilage tissue 2 No
Cerebellum 2 No
Cerebral cortex 2 No
Esophagus 2 No (7/415) (2/2)
Eye 2 No
Gall bladder 2 No
Heart 2 No (2/2)
Hippocampus 2 No
Hypothalamus 2 No
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584) (2/2)
Liver 2 No
Lower urinary tract 2 No (2/2)
Lung 2 No
Lymph node 2 No (1/2)
Mammary gland 2 No
Olfactory lobe 2 No
Oral epithelium 2 No
Ovary 2 No (1/584) (1/2)
Oviduct 2 No (1/2)
Pancreas 2 No (5/584) (2/2)
Parathyroid gland 2 No (2/2)
Peripheral nervous system 2 No (2/2)
Peyer's patch 2 No
Pituitary gland 2 No
Prostate gland 2 No (12/584)
Skeletal muscle 2 No
Skin 2 No (2/2)
Small intestine 2 No (9/584)
Spinal cord 2 No (2/2)
Spleen 2 No (2/584)
Stomach 2 No (12/584) (2/2)
Striatum 2 No
Testis 2 No (2/584) (1/2)
Thymus 2 No
Thyroid gland 2 No (15/584)
Trachea 2 No
Uterus 2 No (1/2)
Vascular system 2 No (2/2)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system
    postnatal mouse
    digestive system
    cardiovascular system
    nervous system
    reproductive system
    musculoskeletal system
    immune system
    integumental system
    trunk
    urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2 (6/485) (4/4)
Ear 2 (1/485) (1/4)
Embryo 2 (1/485) (4/4)
Eye 2 (1/485) (4/4)
Foot 2 (1/485) Image Only
Forebrain 2 (1/485) (3/4)
Forelimb 2 (1/485) (3/4)
Hand 2 (1/485) Image Only
Head 2 (5/485) (4/4)
Heart 2 (1/485) (2/4)
Hindbrain 2 (6/485) (2/4)
Hindlimb 2 (1/485) (3/4)
Liver 2 (1/485) (1/4)
Lung 2 (1/485) (1/4)
Mandibular process 2 (1/485) (1/4)
Maxillary process 2 (1/485) (1/4)
Midbrain 2 (1/485) (3/4)
Oral cavity 2 (1/485) (1/4)
Skin 2 (1/485) (1/4)
Tail 2 (1/485) (4/4)
Tail somite 2 (1/485) (2/4)


Associated Images

Associated Images
  • X-ray: XRay Images Dorso Ventral
    10 Images
  • Adult LacZ: LacZ Images Wholemount
    19 Images
  • X-ray: XRay Images Lateral Orientation
    10 Images
  • Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
    4 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    10 Images
  • Embryo LacZ: LacZ images wholemount
    8 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Arhgef11tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Arhgef11tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene