Gene: Pank3

Order

Name pantothenate kinase 3

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:2387464    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Pank3

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Pank3 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
decreased circulating fructosamine level Pank3tm1b(KOMP)Mbp HOM Female Male postnatal 2.48E-7
decreased bone mineral density Pank3tm1b(KOMP)Mbp HOM Female postnatal 1.39E-6
increased bone mineral density Pank3tm1b(KOMP)Mbp HOM Male postnatal 1.39E-6
decreased erythrocyte cell number Pank3tm1b(KOMP)Mbp HOM Male postnatal 3.11E-6
decreased bone mineral content Pank3tm1b(KOMP)Mbp HOM Female postnatal 7.58E-6
decreased hematocrit Pank3tm1b(KOMP)Mbp HOM Male postnatal 1.9E-5
increased hematocrit Pank3tm1b(KOMP)Mbp HOM Female postnatal 1.9E-5
abnormal behavior Pank3tm1b(KOMP)Mbp HOM Female Male postnatal 6.23E-5
increased bone mineral content Pank3tm1b(KOMP)Mbp HOM Male postnatal 8.02E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415) (2/2)
Aorta 2 No (2/2)
Bone 2 No
Brain 2 No (2/2)
Brainstem 2 No (2/2)
Brown adipose tissue 2 No (2/2)
Cartilage tissue 2 No (2/2)
Cerebellum 2 No (2/2)
Cerebral cortex 2 No (2/2)
Esophagus 2 No (7/415) (2/2)
Eye 2 No (2/2)
Gall bladder 2 No
Heart 2 No (2/2)
Hippocampus 2 No (2/2)
Hypothalamus 2 No (2/2)
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584) (2/2)
Liver 2 No
Lower urinary tract 2 No (2/2)
Lung 2 No (2/2)
Lymph node 2 No
Mammary gland 2 No (1/2)
Olfactory lobe 2 No (2/2)
Oral epithelium 2 No
Ovary 2 No (1/584) (1/2)
Oviduct 2 No (1/2)
Pancreas 2 No (5/584) (2/2)
Parathyroid gland 2 No (2/2)
Peripheral nervous system 2 No (2/2)
Peyer's patch 2 No (2/2)
Pituitary gland 2 No (2/2)
Prostate gland 2 No (12/584)
Skeletal muscle 2 No
Skin 2 No (2/2)
Small intestine 2 No (9/584) (2/2)
Spinal cord 2 No (2/2)
Spleen 2 No (2/584)
Stomach 2 No (12/584) (2/2)
Striatum 2 No
Testis 2 No (2/584) (1/2)
Thymus 2 No
Thyroid gland 2 No (15/584)
Trachea 2 No (2/2)
Uterus 2 No (1/2)
Vascular system 2 No (2/2)
White adipose tissue 2 No (2/2)
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system
    respiratory system
    digestive system
    cardiovascular system
    set of connective tissues
    reproductive system
    adipose tissue
    trunk
    postnatal mouse
    nervous system
    sensory organ
    immune system
    exocrine system
    integumental system
    urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Associated Images

Associated Images
  • Adult LacZ: LacZ Images Wholemount
    23 Images
  • Echo: M-Mode Images
    32 Images
  • X-ray: XRay Images Lateral Orientation
    1 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    1 Images
  • X-ray: XRay Images Dorso Ventral
    1 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Pank3tm1a(KOMP)Mbp KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Pank3tm1b(KOMP)Mbp Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Pank3tm1(NCOM)Cmhd Reporter-tagged deletion allele (with selection cassette)
Vector
Gene