Gene: Gys2

Order

Name glycogen synthase 2

Synonyms
  • glycogen synthase, liver
  • LGS

Status ES CellsMice
tm1a
phenotype data available

Links MGI:2385254    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Gys2

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Gys2 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
decreased circulating glucose level Gys2tm1a(KOMP)Wtsi HOM Female Male postnatal 1.43E-15
decreased body weight Gys2tm1a(KOMP)Wtsi HOM Female Male postnatal 2.58E-10
increased circulating total protein level Gys2tm1a(KOMP)Wtsi HOM Female Male postnatal 4.78E-10
increased circulating calcium level Gys2tm1a(KOMP)Wtsi HOM Female Male postnatal 1.82E-8
increased circulating sodium level Gys2tm1a(KOMP)Wtsi HOM Female Male postnatal 1.43E-6
increased hemoglobin content Gys2tm1a(KOMP)Wtsi HOM Female Male postnatal 7.46E-6
increased total body fat amount Gys2tm1a(KOMP)Wtsi HOM Male postnatal 3.36E-5
abnormal vibrissa morphology Gys2tm1a(KOMP)Wtsi HOM Female postnatal 4.19E-5
increased circulating iron level Gys2tm1a(KOMP)Wtsi HOM Female Male postnatal 6.59E-5
increased lean body mass Gys2tm1a(KOMP)Wtsi HOM Male postnatal 7.16E-5
decreased circulating glycerol level Gys2tm1a(KOMP)Wtsi HOM Female postnatal 7.83E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 5 No
Aorta 5 No
Blood vessel 5 No
Bone 5 No
Brain 5 No
Brainstem 5 No
Brown adipose tissue 5 No
Cartilage tissue 5 No
Cerebellum 5 No
Cerebral cortex 5 No
Eye 5 No
Gall bladder 5 No
Heart 5 No
Hippocampus 5 No
Hypothalamus 5 No
Kidney 5 No (18/584)
Large intestine 5 No (10/584)
Liver 5 No
Lower urinary tract 5 No
Lung 5 No
Lymph node 5 No
Mammary gland 5 No
Esophagus 5 No
Olfactory lobe 5 No
Ovary 5 No (1/584)
Oviduct 5 No
Pancreas 5 No (5/584) (1/5)
Parathyroid gland 5 No
Peripheral nervous system 5 No
Peyer's patch 5 No
Pituitary gland 5 No
Prostate gland 5 No (12/584)
Skeletal muscle tissue 5 No
Skin 5 No
Small intestine 5 No (9/584)
Spinal cord 5 No
Spleen 5 No (2/584)
Stomach 5 No (12/584)
Striatum 5 No
Testis 5 No (2/584) (2/5)
Thymus 5 No
Thyroid gland 5 No (15/584)
Trachea 5 No
Uterus 5 No (1/5)
White adipose tissue 5 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse reproductive system trunk
No expression image was found for this adult tab
No expression data was found for this embryo tab


Secondary lacZ Expression Data
postnatal mouse (5)
  • Gys2tm1a(KOMP)Wtsi
    thyroid gland, HET, Female, WTSI
  • Gys2tm1a(KOMP)Wtsi
    uterus, HET, Female, WTSI
  • Gys2tm1a(KOMP)Wtsi
    testis, HET, Male, WTSI
  • Gys2tm1a(KOMP)Wtsi
    pancreas, HET, Female, WTSI
  • Gys2tm1a(KOMP)Wtsi
    kidney, HET, Female, WTSI
trunk (4)
  • Gys2tm1a(KOMP)Wtsi
    uterus, HET, Female, WTSI
  • Gys2tm1a(KOMP)Wtsi
    testis, HET, Male, WTSI
  • Gys2tm1a(KOMP)Wtsi
    pancreas, HET, Female, WTSI
  • Gys2tm1a(KOMP)Wtsi
    kidney, HET, Female, WTSI
reproductive system (2)
  • Gys2tm1a(KOMP)Wtsi
    uterus, HET, Female, WTSI
  • Gys2tm1a(KOMP)Wtsi
    testis, HET, Male, WTSI
endocrine system (1)
  • Gys2tm1a(KOMP)Wtsi
    thyroid gland, HET, Female, WTSI
urinary system (1)
  • Gys2tm1a(KOMP)Wtsi
    kidney, HET, Female, WTSI

Associated Images

Legacy Phenotype Associated Images
Xray (131)
  • Gys2tm1a(KOMP)Wtsi
    head, HOM, Female, WTSI
  • Gys2tm1a(KOMP)Wtsi
    body, HOM, Female, WTSI
  • Gys2tm1a(KOMP)Wtsi
    body, HOM, Female, WTSI
  • Gys2tm1a(KOMP)Wtsi
    head, HOM, Female, WTSI
  • Gys2tm1a(KOMP)Wtsi
    head, HOM, Female, WTSI

show all 131 images

Skin Histopathology (3)
  • Gys2tm1a(KOMP)Wtsi
    back skin, HOM, Female, WTSI
  • Gys2tm1a(KOMP)Wtsi
    back skin, HOM, Female, WTSI
  • Gys2tm1a(KOMP)Wtsi
    back skin, HOM, Female, WTSI

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Gys2tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene