Gene: Trrap

Order

Name transformation/transcription domain-associated protein

Synonyms transactivation/transformation-domain associated protein

Status ES CellsMice
tm1a
phenotype data available

Links MGI:2153272    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Trrap

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Trrap data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
preweaning lethality, complete penetrance Trraptm1a(EUCOMM)Wtsi HOM Female Male n/a 0.0
increased circulating magnesium level Trraptm1a(EUCOMM)Wtsi HET Male postnatal 5.73E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/2)
Aorta 2 No
Blood vessel 2 No (2/2)
Bone 2 No (1/2)
Brain 2 No (2/2)
Brainstem 2 No
Brown adipose tissue 2 No
Cartilage tissue 2 No (2/2)
Cerebellum 2 No
Cerebral cortex 2 No
Eye 2 No (1/2)
Gall bladder 2 No (1/2)
Heart 2 No (2/2)
Hippocampus 2 No
Hypothalamus 2 No
Kidney 2 No (18/584) (1/2)
Large intestine 2 No (10/584) (2/2)
Liver 2 No
Lower urinary tract 2 No (1/2)
Lung 2 No (1/2)
Lymph node 2 No
Mammary gland 2 No
Esophagus 2 No (2/2)
Olfactory lobe 2 No
Ovary 2 No (1/584) (1/2)
Oviduct 2 No (1/2)
Pancreas 2 No (5/584) (2/2)
Parathyroid gland 2 No
Peripheral nervous system 2 No (2/2)
Peyer's patch 2 No (1/2)
Pituitary gland 2 No (2/2)
Prostate gland 2 No (12/584)
Skeletal muscle tissue 2 No
Skin 2 No (2/2)
Small intestine 2 No (9/584) (2/2)
Spinal cord 2 No (2/2)
Spleen 2 No (2/584) (1/2)
Stomach 2 No (12/584) (2/2)
Striatum 2 No
Testis 2 No (2/584) (1/2)
Thymus 2 No
Thyroid gland 2 No (15/584)
Trachea 2 No (2/2)
Uterus 2 No (1/2)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system respiratory system digestive system cardiovascular system set of connective tissues reproductive system musculoskeletal system trunk postnatal mouse nervous system sensory organ immune system integumental system urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Secondary lacZ Expression Data
postnatal mouse (29)
  • Trraptm1a(EUCOMM)Wtsi
    trachea, HET, Male, WTSI
  • Trraptm1a(EUCOMM)Wtsi
    lower urinary tract, urinary bladder, HET, Male, WTSI
  • Trraptm1a(EUCOMM)Wtsi
    kidney, HET, Female, WTSI
  • Trraptm1a(EUCOMM)Wtsi
    adrenal gland, HET, Female, WTSI
  • Trraptm1a(EUCOMM)Wtsi
    lung, HET, Female, WTSI

show all 29 images

trunk (18)
  • Trraptm1a(EUCOMM)Wtsi
    trachea, HET, Male, WTSI
  • Trraptm1a(EUCOMM)Wtsi
    lower urinary tract, urinary bladder, HET, Male, WTSI
  • Trraptm1a(EUCOMM)Wtsi
    kidney, HET, Female, WTSI
  • Trraptm1a(EUCOMM)Wtsi
    adrenal gland, HET, Female, WTSI
  • Trraptm1a(EUCOMM)Wtsi
    lung, HET, Female, WTSI

show all 18 images

digestive system (6)
  • Trraptm1a(EUCOMM)Wtsi
    large intestine, HET, Female, WTSI
  • Trraptm1a(EUCOMM)Wtsi
    small intestine, HET, Female, WTSI
  • Trraptm1a(EUCOMM)Wtsi
    gall bladder, HET, Male, WTSI
  • Trraptm1a(EUCOMM)Wtsi
    oesophagus, HET, Female, WTSI
  • Trraptm1a(EUCOMM)Wtsi
    gall bladder, HET, Male, WTSI

show all 6 images

nervous system (4)
  • Trraptm1a(EUCOMM)Wtsi
    brain, HET, Female, WTSI
  • Trraptm1a(EUCOMM)Wtsi
    brain, HET, Female, WTSI
  • Trraptm1a(EUCOMM)Wtsi
    pituitary gland, peripheral nervous system, HET, Female, WTSI
  • Trraptm1a(EUCOMM)Wtsi
    spinal cord, HET, Male, WTSI
immune system (3)
  • Trraptm1a(EUCOMM)Wtsi
    mesenteric lymph node, lymph node, HET, Female, WTSI
  • Trraptm1a(EUCOMM)Wtsi
    spleen, HET, Male, WTSI
  • Trraptm1a(EUCOMM)Wtsi
    thymus, HET, Male, WTSI
integumental system (3)
  • Trraptm1a(EUCOMM)Wtsi
    mammary gland, HET, Female, WTSI
  • Trraptm1a(EUCOMM)Wtsi
    skin, HET, Male, WTSI
  • Trraptm1a(EUCOMM)Wtsi
    skin, HET, Female, WTSI
cardiovascular system (2)
  • Trraptm1a(EUCOMM)Wtsi
    heart, HET, Female, WTSI
  • Trraptm1a(EUCOMM)Wtsi
    blood vessel, HET, Female, WTSI
reproductive system (2)
  • Trraptm1a(EUCOMM)Wtsi
    testis, HET, Male, WTSI
  • Trraptm1a(EUCOMM)Wtsi
    ovary, HET, Female, WTSI
respiratory system (2)
  • Trraptm1a(EUCOMM)Wtsi
    trachea, HET, Male, WTSI
  • Trraptm1a(EUCOMM)Wtsi
    lung, HET, Female, WTSI
urinary system (2)
  • Trraptm1a(EUCOMM)Wtsi
    lower urinary tract, urinary bladder, HET, Male, WTSI
  • Trraptm1a(EUCOMM)Wtsi
    kidney, HET, Female, WTSI
endocrine system (1)
  • Trraptm1a(EUCOMM)Wtsi
    adrenal gland, HET, Female, WTSI
exocrine system (1)
  • Trraptm1a(EUCOMM)Wtsi
    mammary gland, HET, Female, WTSI
sensory organ (1)
  • Trraptm1a(EUCOMM)Wtsi
    eye, HET, Male, WTSI
set of connective tissues (1)
  • Trraptm1a(EUCOMM)Wtsi
    cartilage tissue, HET, Female, WTSI

Associated Images

Legacy Phenotype Associated Images
Xray (170)
  • Trraptm1a(EUCOMM)Wtsi
    forearm, HET, Male, WTSI
  • Trraptm1a(EUCOMM)Wtsi
    head, HET, Male, WTSI
  • Trraptm1a(EUCOMM)Wtsi
    head, HET, Male, WTSI
  • Trraptm1a(EUCOMM)Wtsi
    body, HET, Female, WTSI
  • Trraptm1a(EUCOMM)Wtsi
    body, HET, Female, WTSI

show all 170 images

Eye Morphology (1)
  • Trraptm1a(EUCOMM)Wtsi
    eye, eyelids fail to open, HET, Female, WTSI

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Trraptm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Trraptm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene
Trraptm39907(pL1L2_GT2_DelLacZ_bsd)
Vector
Gene