Gene: Hsd17b11

Order

Name hydroxysteroid (17-beta) dehydrogenase 11

Synonyms
  • Dhrs8
  • Pan1b
  • 17beta-HSD11
  • retSDR2

Status ES CellsMice
tm1.1
Mice
tm1
phenotype data available

Links MGI:2149821    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Hsd17b11

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Hsd17b11 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
decreased circulating alanine transaminase level Hsd17b11tm1.1(KOMP)Vlcg HOM Female Male postnatal 6.62E-7
decreased circulating glucose level Hsd17b11tm1.1(KOMP)Vlcg HOM Female Male postnatal 9.75E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415)
Aorta 2 No
Brain 2 No (2/2)
Brainstem 2 No
Brown adipose tissue 2 No
Cartilage tissue 2 No
Cerebellum 2 No
Cerebral cortex 2 No
Epididymis 2 No (18/134)
Esophagus 2 No (7/415)
Eye 2 No (2/2)
Heart 2 No
Hippocampus 2 No
Hypothalamus 2 No
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584) (2/2)
Liver 2 No (2/2)
Lower urinary tract 2 No
Lung 2 No
Lymph node 2 No
Mammary gland 2 No
Midbrain 2 No (2/2)
Olfactory lobe 2 No (2/2)
Ovary 2 No (1/584) (1/2)
Oviduct 2 No
Pancreas 2 No (5/584)
Peripheral nervous system 2 No
Peyer's patch 2 No
Pituitary gland 2 No
Prostate gland 2 No (12/584)
Skeletal muscle 2 No
Skin 2 No (2/2)
Small intestine 2 No (9/584) (2/2)
Spinal cord 2 No
Spleen 2 No (2/584)
Stomach 2 No (12/584) (2/2)
Striatum 2 No
Submandibular gland 2 No (2/132) (2/2)
Testis 2 No (2/584) (1/2)
Thalamus 2 No (2/2)
Thymus 2 No
Thyroid gland 2 No (15/584)
Trachea 2 No
Urinary bladder 2 No
Uterus 2 No (1/2)
Vascular system 2 No
Vesicular gland 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse respiratory system digestive system nervous system sensory organ reproductive system exocrine system integumental system trunk urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2 (6/485) (2/3)
Dorsal root ganglion 2 (1/47) (2/3)
Ear 2 (1/485) (2/3)
Embryo 2 (1/485) (2/3)
Eye 2 (1/485) (2/3)
Foot 2 (1/485)
Forebrain 2 (1/485) (2/3)
Forelimb 2 (1/485)
Fronto-nasal process 2 (1/48) Image Only
Hand 2 (1/485)
Head 2 (5/485) (2/3)
Heart 2 (1/485) (2/3)
Hindbrain 2 (6/485) (2/3)
Hindlimb 2 (1/485)
Liver 2 (1/485)
Lung 2 (1/485) Image Only
Mandibular process 2 (1/485) (2/3)
Maxillary process 2 (1/485)
Midbrain 2 (1/485) (2/3)
Nose 2 (1/51) (2/3)
Oral cavity 2 (1/485) Image Only
Skin 2 (1/485)
Spinal cord 2 (1/50) (2/3)
Tail 2 (1/485) (2/3)
Tail somite 2 (1/485)


Associated Images

Associated Images
  • X-ray: XRay Images Forepaw
    10 Images
  • X-ray: XRay Images Lateral Orientation
    10 Images
  • X-ray: XRay Images Dorso Ventral
    10 Images
  • X-ray: XRay Images Skull Lateral Orientation
    10 Images
  • Embryo LacZ: LacZ images wholemount
    12 Images
  • Electroretinography 2: Rod and cone PDF
    4 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    10 Images
  • Sleep Wake: Wake state (bmp file)
    8 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Hsd17b11tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette)
Vector
Gene
Hsd17b11tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene
Hsd17b11tm221053(L1L2_Bact_P)
Vector
Gene