Gene: Vezt

Order

Name vezatin, adherens junctions transmembrane protein

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:2143698    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Vezt

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Vezt data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
embryonic growth retardation Vezttm1b(EUCOMM)Hmgu HET Female Male embryonic day 9.5 0.0
preweaning lethality, complete penetrance Vezttm1b(EUCOMM)Hmgu HOM Female Male n/a 0.0
decreased circulating glucose level Vezttm1b(EUCOMM)Hmgu HET Female Male postnatal 1.68E-7
hypoactivity Vezttm1b(EUCOMM)Hmgu HET Female Male postnatal 2.19E-6
decreased vertical activity Vezttm1b(EUCOMM)Hmgu HET Female Male postnatal 3.41E-5
abnormal behavior Vezttm1b(EUCOMM)Hmgu HET Female Male postnatal 5.22E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415) (2/2)
Aorta 2 No (2/2)
Brain 2 No (2/2)
Brainstem 2 No (2/2)
Brown adipose tissue 2 No
Cartilage tissue 2 No (2/2)
Cerebellum 2 No (2/2)
Cerebral cortex 2 No (2/2)
Epididymis 2 No (18/134) (1/2)
Esophagus 2 No (7/415) (2/2)
Eye 2 No (2/2)
Heart 2 No (2/2)
Hippocampus 2 No (2/2)
Hypothalamus 2 No (2/2)
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584) (2/2)
Liver 2 No
Lower urinary tract 2 No
Lung 2 No (2/2)
Lymph node 2 No
Mammary gland 2 No
Midbrain 2 No (2/2)
Olfactory lobe 2 No (2/2)
Ovary 2 No (1/584) (1/2)
Oviduct 2 No (1/2)
Pancreas 2 No (5/584)
Peripheral nervous system 2 No (2/2)
Peyer's patch 2 No
Pituitary gland 2 No (2/2)
Prostate gland 2 No (12/584)
Skeletal muscle 2 No
Skin 2 No (2/2)
Small intestine 2 No (9/584) (2/2)
Spinal cord 2 No (2/2)
Spleen 2 No (2/584)
Stomach 2 No (12/584) (2/2)
Striatum 2 No (2/2)
Submandibular gland 2 No (2/132)
Testis 2 No (2/584) (1/2)
Thalamus 2 No (2/2)
Thymus 2 No
Thyroid gland 2 No (15/584)
Trachea 2 No (2/2)
Urinary bladder 2 No (2/2)
Uterus 2 No (1/2)
Vascular system 2 No (2/2)
Vesicular gland 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system postnatal mouse respiratory system digestive system cardiovascular system nervous system set of connective tissues sensory organ reproductive system integumental system trunk urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2 (6/485) (2/2)
Dorsal root ganglion 2 (1/47) Image Only
Ear 2 (1/485) (2/2)
Embryo 2 (1/485) (2/2)
Eye 2 (1/485) (2/2)
Foot 2 (1/485) (2/2)
Forebrain 2 (1/485) (2/2)
Forelimb 2 (1/485) (2/2)
Fronto-nasal process 2 (1/48) Image Only
Hand 2 (1/485) (2/2)
Head 2 (5/485) (2/2)
Heart 2 (1/485) (2/2)
Hindbrain 2 (6/485) (2/2)
Hindlimb 2 (1/485) (2/2)
Liver 2 (1/485)
Lung 2 (1/485) Image Only
Mandibular process 2 (1/485) (2/2)
Maxillary process 2 (1/485) (2/2)
Midbrain 2 (1/485) (2/2)
Nose 2 (1/51) (2/2)
Oral cavity 2 (1/485) Image Only
Skin 2 (1/485) (2/2)
Spinal cord 2 (1/50) (2/2)
Tail 2 (1/485) (2/2)
Tail somite 2 (1/485) (2/2)


Associated Images

Associated Images
  • X-ray: XRay Images Skull Lateral Orientation
    10 Images
  • X-ray: XRay Images Dorso Ventral
    10 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    10 Images
  • X-ray: XRay Images Lateral Orientation
    10 Images
  • X-ray: XRay Images Forepaw
    10 Images
  • Embryo LacZ: LacZ images wholemount
    8 Images
  • Sleep Wake: Wake state (bmp file)
    12 Images
  • Electroretinography 2: Rod and cone PDF
    4 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Vezttm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Vezttm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre)
Vector
Gene