Gene: Unc45a

Order

Name unc-45 myosin chaperone A

Status ES CellsMice
tm1b
Mice
tm1a
phenotype data available

Links MGI:2142246    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Unc45a

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Unc45a data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal lens morphology Unc45atm1b(EUCOMM)Hmgu HET Female Male postnatal 2.15E-6
increased hematocrit Unc45atm1b(EUCOMM)Hmgu HET Male postnatal 3.22E-5
increased erythrocyte cell number Unc45atm1b(EUCOMM)Hmgu HET Male postnatal 4.4E-5
prolonged RR interval Unc45atm1b(EUCOMM)Hmgu HET Female postnatal 5.28E-5
decreased heart rate Unc45atm1b(EUCOMM)Hmgu HET Female postnatal 5.51E-5
preweaning lethality, complete penetrance Unc45atm1b(EUCOMM)Hmgu HOM Female Male n/a 3.17E-4

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415)
Aorta 2 No
Blood 2 No
Bone 2 No
Bone marrow 2 No
Brain 2 No (2/2)
Brainstem 2 No
Brown adipose tissue 2 No
Cartilage tissue 2 No
Cecum 2 No (12/383) (2/2)
Cerebellum 2 No
Cerebral cortex 2 No
Chest bone 2 No (2/2)
Colon 2 No (12/127)
Cranium 2 No
Diaphragm 2 No
Epididymis 2 No (18/134)
Esophagus 2 No (7/415)
Eye 2 No
Gall bladder 2 No
Harderian gland 2 No
Heart 2 No
Hindlimb 2 No
Hippocampus 2 No
Hypothalamus 2 No (1/2)
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584)
Liver 2 No
Lower urinary tract 2 No
Lung 2 No
Lymph node 2 No
Main olfactory bulb 2 No
Mammary gland 2 No
Mesenteric lymph node 2 No
Olfactory lobe 2 No
Oral epithelium 2 No
Ovary 2 No (1/584)
Oviduct 2 No
Pancreas 2 No (5/584)
Parathyroid gland 2 No
Parotid gland 2 No
Penis 2 No (1/2)
Peripheral nervous system 2 No
Peyer's patch 2 No
Pituitary gland 2 No (1/2)
Prostate gland 2 No (12/584)
Sciatic nerve 2 No
Skeletal muscle 2 No
Skin 2 No
Small intestine 2 No (9/584) (2/2)
Spinal cord 2 No
Spleen 2 No (2/584)
Stomach 2 No (12/584) (2/2)
Stomach pyloric region 2 No
Striatum 2 No
Sublingual gland 2 No
Submandibular gland 2 No (2/132) (1/2)
Testis 2 No (2/584) (1/2)
Thymus 2 No
Thyroid gland 2 No (15/584)
Tongue 2 No (5/127)
Trachea 2 No (2/2)
Trigeminal V nerve 2 No
Urinary bladder 2 No (1/2)
Uterus 2 No (1/2)
Vagina 2 No
Vas deferens 2 No (15/388)
Vascular system 2 No
Vesicular gland 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse
    respiratory system
    digestive system
    nervous system
    reproductive system
    musculoskeletal system
    exocrine system
    trunk
    urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Associated Images

Associated Images
  • Adult LacZ: LacZ Images Wholemount
    21 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Unc45atm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Unc45atm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene