Gene: Prom2
Name prominin 2
Status
ES CellsMice
tm1Mice
tm1.1phenotype data available
Links MGI:2138997 Ensembl Gene Ensembl Orthologs
Viability Homozygous - Viable
Phenotype associations for Prom2
All Phenotypes Summary
Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Prom2 data for that phenotype.
Significant Phenotypes
| System | Phenotype | Allele | Zyg | Sex | Life Stage | P Value | Data |
|---|---|---|---|---|---|---|---|
|
|
decreased grip strength | Prom2tm1.1(KOMP)Vlcg | HOM |
|
postnatal | 1.46E-7 | |
|
|
abnormal retina morphology | Prom2tm1.1(KOMP)Vlcg | HET |
|
postnatal | 2.48E-6 | |
|
|
abnormal retina morphology | Prom2tm1.1(KOMP)Vlcg | HOM |
|
postnatal | 2.48E-6 | |
|
|
decreased mean corpuscular volume | Prom2tm1.1(KOMP)Vlcg | HOM |
|
postnatal | 2.65E-6 | |
|
|
increased hemoglobin content | Prom2tm1.1(KOMP)Vlcg | HOM |
|
postnatal | 7.54E-6 | |
|
|
increased erythrocyte cell number | Prom2tm1.1(KOMP)Vlcg | HOM |
|
postnatal | 2.26E-5 | |
|
|
abnormal nail morphology | Prom2tm1.1(KOMP)Vlcg | HOM |
|
postnatal | 4.9E-5 | |
|
|
hyperactivity | Prom2tm1.1(KOMP)Vlcg | HOM |
|
postnatal | 8.71E-5 | |
|
|
decreased circulating insulin level | Prom2tm1.1(KOMP)Vlcg | HOM |
|
postnatal | 9.34E-5 | |
|
|
decreased grip strength | Prom2tm1.1(KOMP)Vlcg | HET |
|
postnatal | 9.38E-5 |
Expression
IMPC lacZ Expression Data
Show expression table
Expression No Expression No Tissue Available Ambiguous
Show Wildtype Expression
| Anatomy | #HET Specimens | HOM Images? | WT Expr | Mutant Expr | Images |
|---|---|---|---|---|---|
| Adrenal gland | 2 | No | (5/393) | ||
| Aorta | 2 | No | (1/562) | ||
| Bone | 2 | No | (1/539) | ||
| Bone marrow | 2 | No | |||
| Brain | 2 | No | (6/562) | (1/2) | |
| Brainstem | 2 | No | (4/562) | (2/2) | |
| Brown adipose tissue | 2 | No | |||
| Cartilage tissue | 2 | No | (1/562) | ||
| Cerebellum | 2 | No | (4/562) | (2/2) | |
| Cerebral cortex | 2 | No | (5/562) | (2/2) | |
| Epididymis | 2 | No | (4/106) | ||
| Esophagus | 2 | No | (2/393) | ||
| Eye | 2 | No | (1/562) | ||
| Heart | 2 | No | (3/562) | ||
| Hippocampus | 2 | No | (5/562) | (2/2) | |
| Hypothalamus | 2 | No | (4/562) | (2/2) | |
| Kidney | 2 | No | (20/562) | (2/2) | |
| Large intestine | 2 | No | (12/562) | ||
| Liver | 2 | No | |||
| Lower urinary tract | 2 | No | (3/562) | ||
| Lung | 2 | No | (3/562) | (2/2) | |
| Lymph node | 2 | No | (1/562) | ||
| Main olfactory bulb | 2 | No | (2/2) | ||
| Mammary gland | 2 | No | |||
| Midbrain | 2 | No | (2/2) | ||
| Olfactory lobe | 2 | No | (4/393) | (2/2) | |
| Ovary | 2 | No | (1/562) | (1/2) | |
| Oviduct | 2 | No | (2/562) | ||
| Pancreas | 2 | No | (6/562) | ||
| Peripheral nervous system | 2 | No | (3/562) | ||
| Peyer's patch | 2 | No | (1/393) | ||
| Pituitary gland | 2 | No | (1/562) | ||
| Prostate gland | 2 | No | (5/562) | ||
| Quadriceps | 2 | No | |||
| Skeletal muscle | 2 | No | |||
| Skin | 2 | No | (1/562) | (1/2) | |
| Small intestine | 2 | No | (11/562) | ||
| Spinal cord | 2 | No | (3/562) | ||
| Spleen | 2 | No | (4/562) | ||
| Stomach | 2 | No | (9/562) | ||
| Striatum | 2 | No | (4/562) | ||
| Submandibular gland | 2 | No | (1/104) | (2/2) | |
| Testis | 2 | No | (4/562) | (1/2) | |
| Thalamus | 2 | No | (2/2) | ||
| Thymus | 2 | No | |||
| Thyroid gland | 2 | No | (16/562) | ||
| Trachea | 2 | No | (3/562) | ||
| Urinary bladder | 2 | No | (2/2) | ||
| Uterus | 2 | No | (2/562) | ||
| Vascular system | 2 | No | (1/393) | ||
| Vesicular gland | 1 | No | |||
| White adipose tissue | 2 | No |
No expression image was found for this adult tab
Expression No Expression No Tissue Available Ambiguous
| Anatomy | #HET Specimens | WT Expr | Mutant Expr | Images |
|---|---|---|---|---|
| Brain | 2 | (6/440) | ||
| Dorsal root ganglion | 1 | (1/3) | ||
| Ear | 2 | (1/440) | ||
| Embryo | 2 | (1/440) | (2/3) | |
| Eye | 2 | (1/440) | (2/3) | |
| Foot | 2 | |||
| Forebrain | 2 | (1/440) | ||
| Forelimb | 2 | (1/440) | (1/3) | |
| Fronto-nasal process | 1 | (1/4) | Image Only | |
| Hand | 2 | |||
| Head | 2 | (5/440) | (1/3) | |
| Heart | 2 | (1/440) | ||
| Hindbrain | 2 | (5/440) | ||
| Hindlimb | 2 | (1/440) | (1/3) | |
| Liver | 2 | (1/440) | ||
| Lung | 2 | (1/440) | ||
| Mandibular process | 2 | (1/440) | (1/3) | |
| Maxillary process | 2 | (1/440) | (1/3) | |
| Midbrain | 2 | (1/440) | ||
| Nose | 2 | (1/5) | (2/2) | |
| Oral cavity | 2 | (1/440) | Image Only | |
| Skin | 2 | (1/440) | (2/3) | |
| Spinal cord | 1 | (1/4) | ||
| Tail | 2 | (1/440) | (1/3) | |
| Tail somite | 2 | (1/440) |
Associated Images
Associated Images
-
X-ray: XRay Images Forepaw
29 Images
-
X-ray: XRay Images Skull Lateral Orientation
29 Images
-
X-ray: XRay Images Skull Dorso Ventral Orientation
29 Images
-
X-ray: XRay Images Dorso Ventral
30 Images
-
X-ray: XRay Images Lateral Orientation
30 Images
-
Sleep Wake: Wake state (bmp file)
22 Images
-
Combined SHIRPA and Dysmorphology
2 Images
-
Embryo LacZ: LacZ images wholemount
8 Images
-
Electroretinography: Rod waveform (pdf format)
7 Images
Order Mouse and ES Cells
| Targeting Detail | Product Ordering | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MGI Allele | Allele Type | Type Map Seq | Vector | ES Cell | Mouse | Tissue Enquiry | ||||||
| Prom2tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) |
|
||||||||||
| Prom2tm1.1(KOMP)Vlcg | Reporter-tagged deletion allele (post Cre, with no selection cassette) |
|
||||||||||
| Prom2tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) |
|
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| Prom2tm2a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) |
|
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