Gene: Gigyf2

Order

Name GRB10 interacting GYF protein 2

Synonyms
  • Tnrc15
  • 2610016F01Rik
  • A830080H02Rik

Status ES CellsMice
tm1b
Mice
tm1a
phenotype data available

Links MGI:2138584    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Gigyf2

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Gigyf2 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
decreased hemoglobin content Gigyf2tm1b(EUCOMM)Wtsi HOM Female Male postnatal 1.56E-8
hypoactivity Gigyf2tm1b(EUCOMM)Wtsi HOM Female Male postnatal 5.66E-8
increased spleen weight Gigyf2tm1b(EUCOMM)Wtsi HOM Female Male postnatal 3.28E-7
increased circulating phosphate level Gigyf2tm1b(EUCOMM)Wtsi HOM Female Male postnatal 2.35E-6
increased fasted circulating glucose level Gigyf2tm1b(EUCOMM)Wtsi HOM Female postnatal 7.88E-6
decreased eosinophil cell number Gigyf2tm1b(EUCOMM)Wtsi HOM Female Male postnatal 1.18E-5
decreased erythrocyte cell number Gigyf2tm1b(EUCOMM)Wtsi HOM Female Male postnatal 2.8E-5
abnormal locomotor behavior Gigyf2tm1b(EUCOMM)Wtsi HOM Female postnatal 3.42E-5
abnormal behavior Gigyf2tm1b(EUCOMM)Wtsi HOM Female Male postnatal 5.97E-5
decreased basophil cell number Gigyf2tm1b(EUCOMM)Wtsi HOM Female Male postnatal 6.51E-5
thrombocytosis Gigyf2tm1b(EUCOMM)Wtsi HOM Female Male postnatal 8.28E-5
tremors Gigyf2tm1b(EUCOMM)Wtsi HOM Female postnatal 9.24E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415)
Aorta 2 No
Bone 2 No
Brain 2 No
Brainstem 2 No
Brown adipose tissue 2 No
Cartilage tissue 2 No
Cerebellum 2 No
Cerebral cortex 2 No
Esophagus 2 No (7/415)
Eye 2 No
Gall bladder 2 No
Heart 2 No
Hippocampus 2 No
Hypothalamus 2 No
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584)
Liver 2 No
Lower urinary tract 2 No
Lung 2 No
Lymph node 2 No
Mammary gland 2 No
Olfactory lobe 2 No
Oral epithelium 2 No
Ovary 2 No (1/584)
Oviduct 2 No
Pancreas 2 No (5/584)
Parathyroid gland 2 No
Peripheral nervous system 2 No
Peyer's patch 2 No
Pituitary gland 2 No
Prostate gland 2 No (12/584)
Skeletal muscle 2 No
Skin 2 No
Small intestine 2 No (9/584)
Spinal cord 2 No
Spleen 2 No (2/584)
Stomach 2 No (12/584)
Striatum 2 No
Testis 2 No (2/584) (1/2)
Thymus 2 No
Thyroid gland 2 No (15/584)
Trachea 2 No
Uterus 2 No
Vascular system 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse
    reproductive system
    trunk
    urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 1 (6/485)
Ear 1 (1/485)
Embryo 1 (1/485)
Eye 1 (1/485)
Foot 1 (1/485)
Forebrain 1 (1/485)
Forelimb 1 (1/485)
Hand 1 (1/485)
Head 1 (5/485)
Heart 1 (1/485)
Hindbrain 1 (6/485)
Hindlimb 1 (1/485)
Liver 1 (1/485)
Lung 1 (1/485)
Mandibular process 1 (1/485)
Maxillary process 1 (1/485)
Midbrain 1 (1/485)
Oral cavity 1 (1/485)
Skin 1 (1/485)
Tail 1 (1/485)
Tail somite 1 (1/485)


Associated Images

Associated Images
  • Adult LacZ: LacZ Images Wholemount
    2 Images
  • Embryo LacZ: LacZ images wholemount
    8 Images

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Gigyf2tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Gigyf2tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene