Gene: Dnajb12

Name DnaJ heat shock protein family (Hsp40) member B12

Synonyms mDj10

Status ES CellsMice
tm1
Mice
tm1.1
phenotype data available

Links MGI:1931881   Ensembl Gene   Ensembl Orthologs

Viability Homozygous - Subviable

Phenotype associations for Dnajb12

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Dnajb12 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal spinal cord morphology Dnajb12tm1.1(KOMP)Vlcg HET Male postnatal 0.0
preweaning lethality, incomplete penetrance Dnajb12tm1.1(KOMP)Vlcg HOM Female Male n/a 0.0
abnormal sleep behavior Dnajb12tm1.1(KOMP)Vlcg HET Female Male postnatal 9.23E-8
increased prepulse inhibition Dnajb12tm1.1(KOMP)Vlcg HET Female Male postnatal 7.67E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/354) (2/2)
Aorta 2 No (2/530) (2/2)
Bone marrow 2 No (2/2)
Brain 2 No (8/530) (2/2)
Brainstem 2 No (5/530) (2/2)
Brown adipose tissue 2 No (2/2)
Cartilage tissue 2 No (1/530) (2/2)
Cerebellum 2 No (6/530) (2/2)
Cerebral cortex 2 No (6/530) (2/2)
Epididymis 2 No (1/103) (1/2)
Esophagus 2 No (1/354) (2/2)
Eye 2 No (1/530) (2/2)
Heart 2 No (4/530) (2/2)
Hippocampus 2 No (7/530) (2/2)
Hypothalamus 2 No (5/529) (2/2)
Kidney 2 No (13/530) (2/2)
Large intestine 2 No (7/530) (2/2)
Liver 2 No (2/2)
Lower urinary tract 2 No (3/530)
Lung 2 No (4/530) (2/2)
Lymph node 2 No (2/530) (2/2)
Mammary gland 2 No (1/2)
Midbrain 2 No (2/2)
Olfactory lobe 2 No (3/354) (2/2)
Ovary 2 No (1/530) (1/2)
Oviduct 2 No (1/530) (1/2)
Pancreas 2 No (2/530) (2/2)
Peripheral nervous system 2 No (4/530) (2/2)
Peyer's patch 2 No (1/354) (2/2)
Pituitary gland 2 No (2/530) (2/2)
Prostate gland 2 No (3/530)
Skeletal muscle 2 No (2/2)
Skin 2 No (2/530) (2/2)
Small intestine 2 No (5/530) (2/2)
Spinal cord 2 No (5/530) (2/2)
Spleen 2 No (3/530) (2/2)
Stomach 2 No (5/530) (2/2)
Striatum 2 No (6/530) (2/2)
Submandibular gland 2 No (2/2)
Testis 2 No (7/530) (1/2)
Thalamus 2 No (2/2)
Thymus 2 No (1/530) (2/2)
Thyroid gland 2 No (11/530) (2/2)
Trachea 2 No (5/530) (2/2)
Urinary bladder 2 No (2/2)
Uterus 2 No (1/530) (1/2)
Vascular system 2 No (1/354)
Vesicular gland 2 No
White adipose tissue 2 No (2/2)
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system
    respiratory system
    digestive system
    cardiovascular system
    set of connective tissues
    reproductive system
    musculoskeletal system
    adipose tissue
    trunk
    postnatal mouse
    nervous system
    sensory organ
    immune system
    exocrine system
    integumental system
    urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 1 (5/413) (1/2)
Dorsal root ganglion 0 No Data Image Only
Ear 1 (1/2)
Embryo 1 (1/2)
Eye 1 (1/2)
Foot 1
Forebrain 1 (1/2)
Forelimb 1 (1/2)
Fronto-nasal process 0 Image Only
Hand 1
Head 1 (4/413) (1/2)
Heart 1 (1/2)
Hindbrain 1 (5/413) (1/2)
Hindlimb 1 (1/2)
Liver 1
Lung 1 Image Only
Mandibular process 1 (1/2)
Maxillary process 1 (1/2)
Midbrain 1 Image Only
Nose 0 No Data Image Only
Oral cavity 1 (1/2)
Skin 1 (1/2)
Spinal cord 1 No Data (1/2)
Tail 1 (1/2)
Tail somite 1 (1/2)


Associated Images

Associated Images
  • X-ray: XRay Images Lateral Orientation
    10 Images
  • Combined SHIRPA and Dysmorphology
    7 Images
  • Embryo LacZ: LacZ images wholemount
    8 Images
  • X-ray: XRay Images Forepaw
    10 Images
  • X-ray: XRay Images Skull Lateral Orientation
    10 Images
  • X-ray: XRay Images Dorso Ventral
    10 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    10 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse
Dnajb12tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene
Dnajb12tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette)
Vector
Gene
Dnajb12tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene