Gene: Bcl11b

Order

Name B cell leukemia/lymphoma 11B

Synonyms
  • B630002E05Rik
  • COUP-TF interacting protein 2
  • Rit1
  • 9130430L19Rik
  • CTIP2

Status ES CellsMice
tm1.1
Mice
tm1
phenotype data available

Links MGI:1929913    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Bcl11b

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Bcl11b data for that phenotype.

Embryo Data: 3D Embryo Imaging
Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal embryo size Bcl11btm1.1(KOMP)Vlcg HET Female Male embryonic day 12.5 0.0
abnormal eyelid fusion Bcl11btm1.1(KOMP)Vlcg HOM Female Male embryonic day 18.5 0.0
abnormal facial morphology Bcl11btm1.1(KOMP)Vlcg HOM Male embryonic day 18.5 0.0
embryonic growth retardation Bcl11btm1.1(KOMP)Vlcg HET Female Male embryonic day 12.5 0.0
hemorrhage Bcl11btm1.1(KOMP)Vlcg HET Male embryonic day 12.5 0.0
preweaning lethality, complete penetrance Bcl11btm1.1(KOMP)Vlcg HOM Female Male n/a 0.0
increased fasted circulating glucose level Bcl11btm1.1(KOMP)Vlcg HET Female Male postnatal 4.77E-6
increased vertical activity Bcl11btm1.1(KOMP)Vlcg HET Female Male postnatal 6.42E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415)
Aorta 2 No
Brain 2 No
Brainstem 2 No
Brown adipose tissue 2 No
Cartilage tissue 2 No
Cerebellum 2 No
Cerebral cortex 2 No
Epididymis 2 No (18/134)
Esophagus 2 No (7/415)
Eye 2 No
Heart 2 No
Hippocampus 2 No
Hypothalamus 2 No
Kidney 2 No (18/584)
Large intestine 2 No (10/584)
Liver 2 No
Lower urinary tract 2 No
Lung 2 No
Lymph node 2 No
Mammary gland 2 No
Midbrain 2 No
Olfactory lobe 2 No
Ovary 2 No (1/584)
Oviduct 2 No
Pancreas 2 No (5/584)
Peripheral nervous system 2 No
Peyer's patch 2 No
Pituitary gland 2 No
Prostate gland 2 No (12/584)
Skeletal muscle 2 No
Skin 2 No
Small intestine 2 No (9/584)
Spinal cord 2 No
Spleen 2 No (2/584)
Stomach 2 No (12/584)
Striatum 2 No
Submandibular gland 2 No (2/132)
Testis 2 No (2/584)
Thalamus 2 No
Thymus 2 No
Thyroid gland 2 No (15/584)
Trachea 2 No
Urinary bladder 2 No
Uterus 2 No
Vascular system 2 No
Vesicular gland 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2 (6/485)
Dorsal root ganglion 2 (1/47)
Ear 2 (1/485)
Embryo 2 (1/485)
Eye 2 (1/485)
Foot 2 (1/485)
Forebrain 2 (1/485)
Forelimb 2 (1/485)
Fronto-nasal process 2 (1/48)
Hand 2 (1/485)
Head 2 (5/485)
Heart 2 (1/485)
Hindbrain 2 (6/485)
Hindlimb 2 (1/485)
Liver 2 (1/485)
Lung 2 (1/485)
Mandibular process 2 (1/485)
Maxillary process 2 (1/485)
Midbrain 2 (1/485)
Nose 2 (1/51)
Oral cavity 2 (1/485)
Skin 2 (1/485)
Spinal cord 2 (1/50)
Tail 2 (1/485)
Tail somite 2 (1/485)


Associated Images

Associated Images
  • Gross Morphology Embryo E18.5
    8 Images
  • X-ray: XRay Images Skull Lateral Orientation
    7 Images
  • X-ray: XRay Images Forepaw
    7 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    7 Images
  • X-ray: XRay Images Lateral Orientation
    7 Images
  • X-ray: XRay Images Dorso Ventral
    7 Images
  • Sleep Wake: Wake state (bmp file)
    1 Images

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Bcl11btm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette)
Vector
Gene
Bcl11btm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene
Bcl11btm1(KOMP)Mbp Reporter-tagged deletion allele (with selection cassette)
Vector
Gene