Gene: Mdn1

Order

Name midasin AAA ATPase 1

Synonyms
  • D4Abb1e
  • 4833432B22Rik
  • LOC213784

Status ES CellsMice
tm1a
phenotype data available

Links MGI:1926159    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Mdn1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Mdn1 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
preweaning lethality, complete penetrance Mdn1tm1a(KOMP)Wtsi HOM Female Male n/a 0.0

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No
Aorta 2 No
Blood vessel 2 No
Bone 2 No
Brain 2 No (2/2)
Brainstem 2 No
Brown adipose tissue 2 No
Cartilage tissue 2 No (2/2)
Cerebellum 2 No
Cerebral cortex 2 No
Eye 2 No
Gall bladder 2 No
Heart 2 No
Hippocampus 2 No
Hypothalamus 2 No
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584)
Liver 2 No
Lower urinary tract 2 No
Lung 2 No
Lymph node 2 No
Mammary gland 2 No
Esophagus 2 No
Olfactory lobe 2 No
Ovary 2 No (1/584) (1/2)
Oviduct 2 No
Pancreas 2 No (5/584)
Parathyroid gland 2 No (2/2)
Peripheral nervous system 2 No (2/2)
Peyer's patch 2 No
Pituitary gland 2 No
Prostate gland 2 No (12/584)
Skeletal muscle tissue 2 No (2/2)
Skin 2 No
Small intestine 2 No (9/584)
Spinal cord 2 No (2/2)
Spleen 2 No (2/584)
Stomach 2 No (12/584)
Striatum 2 No
Testis 2 No (2/584) (1/2)
Thymus 2 No
Thyroid gland 2 No (15/584) (2/2)
Trachea 2 No (2/2)
Uterus 2 No (1/2)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse respiratory system endocrine system nervous system set of connective tissues reproductive system musculoskeletal system trunk urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Secondary lacZ Expression Data
postnatal mouse (9)
  • Mdn1tm1a(KOMP)Wtsi
    skeletal muscle tissue, HET, Female, WTSI
  • Mdn1tm1a(KOMP)Wtsi
    peripheral nervous system, HET, Female, WTSI
  • Mdn1tm1a(KOMP)Wtsi
    brain, HET, Male, WTSI
  • Mdn1tm1a(KOMP)Wtsi
    ovary, HET, Female, WTSI
  • Mdn1tm1a(KOMP)Wtsi
    brain, HET, Male, WTSI

show all 9 images

trunk (5)
  • Mdn1tm1a(KOMP)Wtsi
    ovary, HET, Female, WTSI
  • Mdn1tm1a(KOMP)Wtsi
    trachea, HET, Male, WTSI
  • Mdn1tm1a(KOMP)Wtsi
    testis, HET, Male, WTSI
  • Mdn1tm1a(KOMP)Wtsi
    kidney, HET, Female, WTSI
  • Mdn1tm1a(KOMP)Wtsi
    spinal cord, HET, Female, WTSI
nervous system (4)
  • Mdn1tm1a(KOMP)Wtsi
    peripheral nervous system, HET, Female, WTSI
  • Mdn1tm1a(KOMP)Wtsi
    brain, HET, Male, WTSI
  • Mdn1tm1a(KOMP)Wtsi
    brain, HET, Male, WTSI
  • Mdn1tm1a(KOMP)Wtsi
    spinal cord, HET, Female, WTSI
reproductive system (2)
  • Mdn1tm1a(KOMP)Wtsi
    ovary, HET, Female, WTSI
  • Mdn1tm1a(KOMP)Wtsi
    testis, HET, Male, WTSI
musculoskeletal system (1)
  • Mdn1tm1a(KOMP)Wtsi
    skeletal muscle tissue, HET, Female, WTSI
respiratory system (1)
  • Mdn1tm1a(KOMP)Wtsi
    trachea, HET, Male, WTSI
urinary system (1)
  • Mdn1tm1a(KOMP)Wtsi
    kidney, HET, Female, WTSI

Associated Images

Legacy Phenotype Associated Images
Xray (163)
  • Mdn1tm1a(KOMP)Wtsi
    body, WT, Male, WTSI
  • Mdn1tm1a(KOMP)Wtsi
    body, WT, Male, WTSI
  • Mdn1tm1a(KOMP)Wtsi
    head, WT, Male, WTSI
  • Mdn1tm1a(KOMP)Wtsi
    body, WT, Male, WTSI
  • Mdn1tm1a(KOMP)Wtsi
    head, WT, Male, WTSI

show all 163 images

Skin Histopathology (3)
  • Mdn1tm1a(KOMP)Wtsi
    back skin, HET, Female, WTSI
  • Mdn1tm1a(KOMP)Wtsi
    back skin, HET, Female, WTSI
  • Mdn1tm1a(KOMP)Wtsi
    back skin, HET, Female, WTSI
Eye Morphology (1)
  • Mdn1tm1a(KOMP)Wtsi
    eye, corneal opacity, cornea/lens fusion, HET, Male, WTSI

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Mdn1tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Mdn1tm300173(L1L2_Bact_P)
Vector
Gene