Gene: Zfp536

Order

Name zinc finger protein 536

Synonyms 9630010P11Rik

Status ES CellsMice
tm1
Mice
tm1.1
phenotype data available

Links MGI:1926102    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Zfp536

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Zfp536 data for that phenotype.

Embryo Data: 3D Embryo Imaging
Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
cyanosis Zfp536tm1.1(KOMP)Wtsi HOM Female Male embryonic day 18.5 0.0
preweaning lethality, complete penetrance Zfp536tm1.1(KOMP)Wtsi HOM Female Male n/a 0.0
respiratory system phenotype Zfp536tm1.1(KOMP)Wtsi HOM Female Male embryonic day 18.5 0.0
increased mean corpuscular hemoglobin concentration Zfp536tm1.1(KOMP)Wtsi HET Female Male postnatal 4.65E-8
increased prepulse inhibition Zfp536tm1.1(KOMP)Wtsi HET Female Male postnatal 6.54E-5
decreased blood urea nitrogen level Zfp536tm1.1(KOMP)Wtsi HET Female Male postnatal 8.5E-5
increased hemoglobin content Zfp536tm1.1(KOMP)Wtsi HET Female Male postnatal 8.61E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415) (2/2)
Aorta 2 No
Brain 2 No (2/2)
Brainstem 2 No (2/2)
Brown adipose tissue 2 No
Cartilage tissue 2 No
Cerebellum 2 No (2/2)
Cerebral cortex 2 No (2/2)
Epididymis 2 No (18/134)
Esophagus 2 No (7/415)
Eye 2 No (2/2)
Heart 2 No (2/2)
Hippocampus 2 No (2/2)
Hypothalamus 2 No (2/2)
Kidney 2 No (18/584)
Large intestine 2 No (10/584) (2/2)
Liver 2 No
Lower urinary tract 2 No
Lung 2 No
Lymph node 2 No
Mammary gland 2 No
Midbrain 2 No (2/2)
Olfactory lobe 2 No (2/2)
Ovary 2 No (1/584)
Oviduct 2 No
Pancreas 2 No (5/584)
Peripheral nervous system 2 No (2/2)
Peyer's patch 2 No
Pituitary gland 2 No (2/2)
Prostate gland 2 No (12/584)
Skeletal muscle 2 No
Skin 2 No (2/2)
Small intestine 2 No (9/584) (2/2)
Spinal cord 2 No (2/2)
Spleen 2 No (2/584)
Stomach 2 No (12/584) (2/2)
Striatum 2 No
Submandibular gland 2 No (2/132)
Testis 2 No (2/584) (1/2)
Thalamus 2 No (2/2)
Thymus 2 No
Thyroid gland 2 No (15/584)
Trachea 2 No
Urinary bladder 2 No (2/2)
Uterus 2 No
Vascular system 2 No
Vesicular gland 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system postnatal mouse digestive system cardiovascular system nervous system sensory organ reproductive system integumental system trunk urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2 (6/485) (2/3)
Dorsal root ganglion 1 (1/47) Image Only
Ear 2 (1/485) (2/3)
Embryo 2 (1/485) (2/3)
Eye 2 (1/485) (2/3)
Foot 2 (1/485)
Forebrain 2 (1/485) (2/3)
Forelimb 2 (1/485)
Fronto-nasal process 1 (1/48) Image Only
Hand 2 (1/485)
Head 2 (5/485) (2/3)
Heart 2 (1/485)
Hindbrain 2 (6/485) (2/3)
Hindlimb 2 (1/485)
Liver 2 (1/485)
Lung 2 (1/485) Image Only
Mandibular process 2 (1/485) (2/3)
Maxillary process 2 (1/485) (2/3)
Midbrain 2 (1/485) (2/3)
Nose 1 (1/51) Image Only
Oral cavity 2 (1/485) (1/3)
Skin 2 (1/485) (2/3)
Spinal cord 1 (1/50) (1/1)
Tail 2 (1/485) (2/3)
Tail somite 2 (1/485) (1/3)


Associated Images

Associated Images
  • Embryo LacZ: LacZ images wholemount
    8 Images
  • X-ray: XRay Images Lateral Orientation
    16 Images
  • X-ray: XRay Images Forepaw
    15 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    16 Images
  • X-ray: XRay Images Dorso Ventral
    16 Images
  • X-ray: XRay Images Skull Lateral Orientation
    16 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Zfp536tm1(KOMP)Wtsi Reporter-tagged deletion allele (with selection cassette)
Vector
Gene
Zfp536tm1.1(KOMP)Wtsi Reporter-tagged deletion allele (post Cre, with no selection cassette)
Vector
Gene
Zfp536tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene