Gene: Rhot1

Name ras homolog family member T1

Synonyms
  • 2210403N23Rik
  • FLJ11040
  • Arht1
  • Miro1
  • C430039G08Rik

Status ES CellsMice
tm1a
phenotype data available

Links MGI:1926078   Ensembl Gene   Ensembl Orthologs

Viability Homozygous - Lethal

Phenotype associations for Rhot1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Rhot1 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
preweaning lethality, complete penetrance Rhot1tm1a(EUCOMM)Wtsi HOM Female Male n/a 0.0

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/2)
Aorta 2 No (1/562)
Blood vessel 2 No
Bone 2 No (1/539)
Brain 2 No (5/562) (2/2)
Brainstem 2 No (4/562)
Brown adipose tissue 2 No (1/2)
Cartilage tissue 2 No (1/562) (2/2)
Cerebellum 2 No (4/562)
Cerebral cortex 2 No (5/562)
Eye 2 No (1/562)
Gall bladder 2 No (1/2)
Heart 2 No (3/562) (2/2)
Hippocampus 2 No (5/562)
Hypothalamus 2 No (4/562)
Kidney 2 No (19/562) (2/2)
Large intestine 2 No (12/562) (1/2)
Liver 2 No (2/2)
Lower urinary tract 2 No (3/562) (1/2)
Lung 2 No (3/562) (2/2)
Lymph node 2 No (1/562)
Mammary gland 2 No
Esophagus 2 No (2/2)
Olfactory lobe 2 No
Ovary 2 No (1/562) (1/2)
Oviduct 2 No (2/562) (1/2)
Pancreas 2 No (6/562) (1/2)
Parathyroid gland 2 No (2/540) (2/2)
Peripheral nervous system 2 No (3/562) (2/2)
Peyer's patch 2 No (1/2)
Pituitary gland 2 No (1/562) (2/2)
Prostate gland 2 No (5/562)
Skeletal muscle tissue 2 No (2/2)
Skin 2 No (1/562) (1/2)
Small intestine 2 No (11/562) (1/2)
Spinal cord 2 No (3/562) (2/2)
Spleen 2 No (4/562) (1/2)
Stomach 2 No (9/562) (2/2)
Striatum 2 No (4/562)
Testis 2 No (3/562) (1/2)
Thymus 2 No (1/2)
Thyroid gland 2 No (16/562) (2/2)
Trachea 2 No (3/562) (2/2)
Uterus 2 No (2/562) (1/2)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system respiratory system digestive system cardiovascular system set of connective tissues reproductive system musculoskeletal system adipose tissue trunk postnatal mouse nervous system immune system integumental system urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Secondary lacZ Expression Data
trunk (15)
  • Rhot1tm1a(EUCOMM)Wtsi
    SPLEEN, HET, Female, WTSI
  • Rhot1tm1a(EUCOMM)Wtsi
    ESOPHAGUS, HET, Female, WTSI
  • Rhot1tm1a(EUCOMM)Wtsi
    HEART, HET, Female, WTSI
  • Rhot1tm1a(EUCOMM)Wtsi
    KIDNEY, HET, Female, WTSI
  • Rhot1tm1a(EUCOMM)Wtsi
    LIVER, GALL BLADDER, HET, Female, WTSI

show all 15 images

digestive system (4)
  • Rhot1tm1a(EUCOMM)Wtsi
    ESOPHAGUS, HET, Female, WTSI
  • Rhot1tm1a(EUCOMM)Wtsi
    LIVER, GALL BLADDER, HET, Female, WTSI
  • Rhot1tm1a(EUCOMM)Wtsi
    SMALL INTESTINE, HET, Female, WTSI
  • Rhot1tm1a(EUCOMM)Wtsi
    LARGE INTESTINE, HET, Female, WTSI
nervous system (4)
  • Rhot1tm1a(EUCOMM)Wtsi
    PITUITARY GLAND, PERIPHERAL NERVOUS SYSTEM, HET, Female, WTSI
  • Rhot1tm1a(EUCOMM)Wtsi
    BRAIN, HET, Male, WTSI
  • Rhot1tm1a(EUCOMM)Wtsi
    BRAIN, HET, Male, WTSI
  • Rhot1tm1a(EUCOMM)Wtsi
    SPINAL CORD, HET, Female, WTSI
immune system (3)
  • Rhot1tm1a(EUCOMM)Wtsi
    SPLEEN, HET, Female, WTSI
  • Rhot1tm1a(EUCOMM)Wtsi
    LYMPH NODE, HET, Female, WTSI
  • Rhot1tm1a(EUCOMM)Wtsi
    THYMUS, HET, Female, WTSI
endocrine system (2)
  • Rhot1tm1a(EUCOMM)Wtsi
    PARATHYROID GLAND, HET, Female, WTSI
  • Rhot1tm1a(EUCOMM)Wtsi
    ADRENAL GLAND, HET, Female, WTSI
integumental system (2)
  • Rhot1tm1a(EUCOMM)Wtsi
    SKIN, HET, Female, WTSI
  • Rhot1tm1a(EUCOMM)Wtsi
    MAMMARY GLAND, HET, Female, WTSI
reproductive system (2)
  • Rhot1tm1a(EUCOMM)Wtsi
    OVARY, UTERUS, OVIDUCT, HET, Female, WTSI
  • Rhot1tm1a(EUCOMM)Wtsi
    TESTIS, HET, Male, WTSI
urinary system (2)
  • Rhot1tm1a(EUCOMM)Wtsi
    KIDNEY, HET, Female, WTSI
  • Rhot1tm1a(EUCOMM)Wtsi
    URINARY BLADDER, LOWER URINARY TRACT, HET, Female, WTSI
adipose tissue (1)
  • Rhot1tm1a(EUCOMM)Wtsi
    BROWN ADIPOSE TISSUE, HET, Female, WTSI
cardiovascular system (1)
  • Rhot1tm1a(EUCOMM)Wtsi
    HEART, HET, Female, WTSI
exocrine system (1)
  • Rhot1tm1a(EUCOMM)Wtsi
    MAMMARY GLAND, HET, Female, WTSI
musculoskeletal system (1)
  • Rhot1tm1a(EUCOMM)Wtsi
    BONE, HET, Female, WTSI
respiratory system (1)
  • Rhot1tm1a(EUCOMM)Wtsi
    LUNG, HET, Female, WTSI
set of connective tissues (1)
  • Rhot1tm1a(EUCOMM)Wtsi
    BROWN ADIPOSE TISSUE, HET, Female, WTSI

Associated Images

Legacy Phenotype Associated Images
Xray (159)
  • Rhot1tm1a(EUCOMM)Wtsi
    TRUNK, WT, Female, WTSI
  • Rhot1tm1a(EUCOMM)Wtsi
    TRUNK, WT, Female, WTSI
  • Rhot1tm1a(EUCOMM)Wtsi
    WT, Female, WTSI
  • Rhot1tm1a(EUCOMM)Wtsi
    WT, Female, WTSI
  • Rhot1tm1a(EUCOMM)Wtsi
    LOWER ARM, WT, Female, WTSI

show all 159 images

Brain Histopathology (8)
  • Rhot1tm1a(EUCOMM)Wtsi
    WT, Male, WTSI
  • Rhot1tm1a(EUCOMM)Wtsi
    WT, Male, WTSI
  • Rhot1tm1a(EUCOMM)Wtsi
    increased retrosplenial granular cortex size, HET, Male, WTSI
  • Rhot1tm1a(EUCOMM)Wtsi
    WT, Male, WTSI
  • Rhot1tm1a(EUCOMM)Wtsi
    WT, Male, WTSI

show all 8 images

Skin Histopathology (4)
  • Rhot1tm1a(EUCOMM)Wtsi
    FOOT DIGIT 4, HET, Female, WTSI
  • Rhot1tm1a(EUCOMM)Wtsi
    FOOT DIGIT 4, HET, Female, WTSI
  • Rhot1tm1a(EUCOMM)Wtsi
    FOOT DIGIT 4, HET, Female, WTSI
  • Rhot1tm1a(EUCOMM)Wtsi
    FOOT DIGIT 4, HET, Female, WTSI

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Rhot1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Rhot1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Rhot1tm16(L1L2_gt1_Del_LacZ)
Vector
Gene
Rhot1tm16(pL1L2_frt15_BetactinBSD_frt14_neo_Rox)
Vector
Gene
Rhot1tm16(pL1L2_GT1_DelLacZ_bsd)
Vector
Gene