banner
Genes Phenotypes Help, News, Blog

Gene: Alg9 MGI:1924753

Log in to follow

Gene Summary

Name:
ALG9 alpha-1,2-mannosyltransferase
Synonyms:
B430313H07Rik,  8230402H15Rik,  Dibd1

Order Alleles

IMPC Data Collections

IMPC Phenotype Summary

Significant
Not Significant
Not tested

View all our phenotype data below

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

Phenotype System Allele Zyg Sex Life Stage P Value
embryonic lethality prior to tooth bud stage Alg9em1(IMPC)J HOM   E12.5 0.00
increased total body fat amount Alg9em1(IMPC)J HET   Early adult 6.64×10-05
preweaning lethality, complete penetrance Alg9em1(IMPC)J HOM   Early adult 0.00

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Eye Morphology

Images Ophthalmoscopy

9 Images

View images
X-ray

XRay Images Skull Lateral Orientation

10 Images

View images
X-ray

XRay Images Skull Dorso Ventral Orientation

10 Images

View images
X-ray

XRay Images Forepaw

10 Images

View images
X-ray

XRay Images Whole Body Dorso Ventral

10 Images

View images
X-ray

XRay Images Whole Body Lateral Orientation

10 Images

View images
Combined SHIRPA and Dysmorphology

Images

2 Images

View images
PDF thumbnail PDF
Auditory Brain Stem Response

Click-evoked + 6 to 30kHz tone waveforms (pdf format)

7 Images

View images

Human diseases caused by Alg9 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

The table below shows human diseases associated to Alg9 by orthology or direct annotation.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Alg9-Cdg
Omphalocele, Lipodystrophy ORPHA:79328
Gillessen-Kaesbach-Nishimura Syndrome
Omphalocele, Flexion contracture, Congenital diaphragmatic hernia OMIM:263210
Congenital Disorder Of Glycosylation, Type Il
OMIM:608776
Autosomal Dominant Polycystic Kidney Disease
ORPHA:730

The table below shows human diseases predicted to be associated to Alg9 by phenotypic similarity.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Alg9-Cdg
Omphalocele, Lipodystrophy ORPHA:79328
Gillessen-Kaesbach-Nishimura Syndrome
Omphalocele, Flexion contracture, Congenital diaphragmatic hernia OMIM:263210
Congenital Disorder Of Glycosylation, Type Il
OMIM:608776
Autosomal Dominant Polycystic Kidney Disease
ORPHA:730

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Alg9

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Alg9.

No publications found that use IMPC mice or data for Alg9.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

MGI Allele Allele Type Produced
Alg9tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Alg9em1(IMPC)J Exon Deletion Mice
Alg9tm1e(EUCOMM)Wtsi Targeted, non-conditional allele ES Cells

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter