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Gene: Slc30a9 MGI:1923690

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Gene Summary

Name:
solute carrier family 30 (zinc transporter), member 9
Synonyms:
GAC63,  2310024J23Rik

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IMPC Phenotype Summary

Significant
Not Significant
Not tested

View all our phenotype data below

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

Phenotype System Allele Zyg Sex Life Stage P Value
abnormal vitelline vasculature morphology Slc30a9em1(IMPC)Bay HOM E9.5 0.00
abnormal embryo size Slc30a9em1(IMPC)Bay HOM E9.5 0.00
abnormal embryo turning Slc30a9em1(IMPC)Bay HOM E9.5 0.00
preweaning lethality, complete penetrance Slc30a9em1(IMPC)Bay HOM   Early adult 0.00
embryonic growth retardation Slc30a9em1(IMPC)Bay HET E12.5 0.00
abnormal placenta development Slc30a9em1(IMPC)Bay HET E12.5 0.00
embryonic growth retardation Slc30a9em1(IMPC)Bay HOM E9.5 0.00
abnormal embryo size Slc30a9em1(IMPC)Bay HET E12.5 0.00
abnormal embryo development Slc30a9em1(IMPC)Bay HOM E9.5 0.00
abnormal hindbrain development Slc30a9em1(IMPC)Bay HOM E9.5 0.00
abnormal neural tube closure Slc30a9em1(IMPC)Bay HOM E9.5 0.00
abnormal midbrain development Slc30a9em1(IMPC)Bay HOM E9.5 0.00
abnormal forebrain development Slc30a9em1(IMPC)Bay HOM E9.5 0.00
abnormal heart morphology Slc30a9em1(IMPC)Bay HOM E9.5 0.00
abnormal somite shape Slc30a9em1(IMPC)Bay HOM E9.5 0.00
abnormal pharyngeal arch morphology Slc30a9em1(IMPC)Bay HOM E9.5 0.00
abnormal neural tube morphology Slc30a9em1(IMPC)Bay HOM E9.5 0.00
embryonic lethality prior to tooth bud stage Slc30a9em1(IMPC)Bay HOM   E12.5 0.00
abnormal heart looping Slc30a9em1(IMPC)Bay HOM E9.5 0.00
abnormal tail bud morphology Slc30a9em1(IMPC)Bay HOM E9.5 0.00
abnormal placenta size Slc30a9em1(IMPC)Bay HET E12.5 0.00

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
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Viewing: all phenotypes

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

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MicroCT E9.5

Embryo reconstruction

5 Images

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Electrocardiogram (ECG)

Waveform Image

1 Images

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Human diseases caused by Slc30a9 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

The table below shows human diseases associated to Slc30a9 by orthology or direct annotation.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Birk-Landau-Perez Syndrome
Growth delay, Intrauterine growth retardation OMIM:617595

The table below shows human diseases predicted to be associated to Slc30a9 by phenotypic similarity.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Muscular Dystrophy-Dystroglycanopathy (Congenital With Brain And Eye Anomalies), Type A, 10
Neural tube defect OMIM:615041
Lambert Syndrome
Intrauterine growth retardation, Branchial anomaly, Ventricular septal defect ORPHA:1296
Neural Tube Defects, Folate-Sensitive
Spinal dysraphism OMIM:601634
Myelopathy, Htlv-1-Associated
Myelopathy OMIM:159580
Spina Bifida-Hypospadias Syndrome
Spina bifida, Spinal dysraphism ORPHA:3176
Verheij Syndrome
Branchial cyst, Ventricular septal defect, Short stature, Short neck, Growth delay, Intrauterine ... OMIM:615583
X-Linked Mandibulofacial Dysostosis
Short stature, Branchial anomaly, Pulmonic stenosis, Webbed neck, Abnormal mitral valve morphology ORPHA:1131
Branchiogenic-Deafness Syndrome
Branchial cyst, Branchial fistula, Short stature OMIM:609166
Fryns Microphthalmia Syndrome
Neural tube defect OMIM:600776
Dysraphism-Cleft Lip/Palate-Limb Reduction Defects Syndrome
Ventricular septal defect, Hypoplastic left heart, Anencephaly, Spina bifida ORPHA:2476
Branchiootic Syndrome 3
Branchial cyst OMIM:608389
Aminopterin/Methotrexate Embryofetopathy
Encephalocele, Ventricular septal defect, Short stature, Situs inversus totalis, Hydrocephalus, M... ORPHA:1908
Aplasia Cutis Congenita
Spinal dysraphism ORPHA:1114
Branchiootic Syndrome 1
Branchial fistula OMIM:602588
X-Linked Microcephaly-Growth Retardation-Prognathism-Cryptorchidism Syndrome
Branchial cyst, Severe postnatal growth retardation ORPHA:435938
Neurodevelopmental Disorder-Craniofacial Dysmorphism-Cardiac Defect-Skeletal Anomalies Syndrome
Bicuspid aortic valve, Ventricular septal defect, Increased nuchal translucency, Abnormal heart m... ORPHA:453499
Branchiogenic Deafness Syndrome
Branchial cyst, Branchial fistula, Short stature ORPHA:50815
Anencephaly 1
Anencephaly, Spina bifida OMIM:206500
Holoprosencephaly
Encephalocele, Ventricular septal defect, Abnormal pulmonary valve morphology, Short neck, Hydroc... ORPHA:2162
Blepharocheilodontic Syndrome 1
Neural tube defect OMIM:119580
Alg3-Cdg
Neural tube defect, Cardiomyopathy ORPHA:79321
Branchiootic Syndrome
Branchial fistula ORPHA:52429
Isolated Posterior Meningocele
Limitation of neck motion, Meningocele, Lipomyelomeningocele, Hydrocephalus, Neural tube defect, ... ORPHA:268810
Distal 22Q11.2 Microdeletion Syndrome
Branchial fistula, Ventricular septal defect, Short stature, Growth delay, Atrial septal defect, ... ORPHA:261330
Bor Syndrome
Branchial cyst ORPHA:107
Distal 22Q11.2 Microduplication Syndrome
Branchial fistula, Ventricular septal defect, Patent ductus arteriosus, Hydrocephalus, Low poster... ORPHA:261337
Branchiootorenal Syndrome 1
Branchial cyst, Branchial fistula OMIM:113650
Craniorachischisis
Cervical spina bifida, Myelomeningocele, Anencephaly, Sirenomelia, Spinal dysraphism ORPHA:63260
Oligomeganephronia
Branchial cyst, Secundum atrial septal defect ORPHA:2260
Neurodevelopmental Disorder-Craniofacial Dysmorphism-Cardiac Defect-Skeletal Anomalies Syndrome Due To A Point Mutation
Bicuspid aortic valve, Ventricular septal defect, Increased nuchal translucency, Abnormal heart m... ORPHA:453504
Neurodevelopmental Disorder-Craniofacial Dysmorphism-Cardiac Defect-Skeletal Anomalies Syndrome Due To 9Q21.3 Microdeletion
Bicuspid aortic valve, Ventricular septal defect, Increased nuchal translucency, Abnormal heart m... ORPHA:352665
Vertebral, Cardiac, Renal, And Limb Defects Syndrome 1
Short stature, Spinal dysraphism, Hypoplastic left heart, Aortic valve stenosis, Atrial septal de... OMIM:617660
Aprosencephaly Syndrome
Aprosencephaly, Anencephaly OMIM:207770
Facial Dysmorphism-Developmental Delay-Behavioral Abnormalities Syndrome Due To Wac Point Mutation
Branchial anomaly ORPHA:466950
8Q24.3 Microdeletion Syndrome
Branchial cyst, Infancy onset short-trunk short stature, Ventricular septal defect, Short stature... ORPHA:508488
Treacher-Collins Syndrome
Encephalocele, Branchial fistula, Patent ductus arteriosus ORPHA:861
Branchial Arch Abnormalities, Choanal Atresia, Athelia, Hearing Loss, And Hypothyroidism Syndrome
Branchial cyst, Natal tooth, Short stature, Atrial septal defect, Intrauterine growth retardation... OMIM:620186
Iniencephaly
Encephalocele, Rhizomelia, Spina bifida, Myelomeningocele, Hydrocephalus, Anencephaly, Spinal dys... ORPHA:63259
Sacral Defect With Anterior Meningocele
Myeloschisis, Myelomeningocele, Meningocele, Hydrocephalus, Dermal sinus tract OMIM:600145
Craniofacial Microsomia 1
Occipital encephalocele, Ventricular septal defect, Patent ductus arteriosus, Hydrocephalus, Bran... OMIM:164210
Branchiooculofacial Syndrome
Short neck, Postnatal growth retardation, Low posterior hairline, Branchial anomaly, Intrauterine... OMIM:113620
Witteveen-Kolk Syndrome
Growth delay, Branchial fistula, Short stature, Intrauterine growth retardation OMIM:613406
Alobar Holoprosencephaly
Short stature, Hydrocephalus, Abnormal heart morphology, Growth delay, Neural tube defect ORPHA:93925
Midline Interhemispheric Variant Of Holoprosencephaly
Short stature, Hydrocephalus, Abnormal heart morphology, Growth delay, Neural tube defect ORPHA:93926
Lobar Holoprosencephaly
Short stature, Hydrocephalus, Abnormal heart morphology, Growth delay, Neural tube defect ORPHA:93924
Semilobar Holoprosencephaly
Short stature, Hydrocephalus, Abnormal heart morphology, Growth delay, Neural tube defect ORPHA:220386
Schinzel-Giedion Syndrome
Delayed eruption of teeth, Short neck, Abnormal heart morphology, Neural tube defect, Umbilical h... ORPHA:798
Aprosencephaly And Cerebellar Dysgenesis
Aprosencephaly OMIM:601374
Birk-Landau-Perez Syndrome
Growth delay, Intrauterine growth retardation OMIM:617595

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Slc30a9

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Slc30a9.

No publications found that use IMPC mice or data for Slc30a9.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

MGI Allele Allele Type Produced
Slc30a9tm1e(KOMP)Wtsi Targeted, non-conditional allele ES Cells
Slc30a9tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Slc30a9em1(IMPC)Bay Exon Deletion Mice

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