Gene: Tmem14a

Order

Name transmembrane protein 14A

Synonyms
  • PTD011
  • 5730496E24Rik

Status ES CellsMice
tm2a
Mice
tm2b
phenotype data available

Links MGI:1922962    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Tmem14a

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Tmem14a data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
hyperactivity Tmem14atm2b(KOMP)Wtsi HET Female postnatal 4.31E-7
decreased leukocyte cell number Tmem14atm2b(KOMP)Wtsi HET Female postnatal 6.68E-6
decreased total body fat amount Tmem14atm2b(KOMP)Wtsi HET Female postnatal 1.13E-5
increased total body fat amount Tmem14atm2b(KOMP)Wtsi HET Male postnatal 1.13E-5
decreased circulating chloride level Tmem14atm2b(KOMP)Wtsi HET Female Male postnatal 2.25E-5
decreased lean body mass Tmem14atm2b(KOMP)Wtsi HET Male postnatal 8.24E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (5/393) (1/2)
Aorta 2 No (1/562) (2/2)
Brain 2 No (6/562) (2/2)
Brainstem 2 No (4/562) (2/2)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/562) (2/2)
Cerebellum 2 No (4/562) (2/2)
Cerebral cortex 2 No (5/562) (2/2)
Epididymis 2 No (4/106) (1/2)
Esophagus 2 No (2/393)
Eye 2 No (1/562) (1/2)
Heart 2 No (3/562) (2/2)
Hippocampus 2 No (5/562) (2/2)
Hypothalamus 2 No (4/562) (2/2)
Kidney 2 No (20/562) (2/2)
Large intestine 2 No (12/562)
Liver 2 No
Lower urinary tract 2 No (3/562)
Lung 2 No (3/562) (2/2)
Lymph node 2 No (1/562)
Mammary gland 2 No
Midbrain 2 No (2/2)
Olfactory lobe 2 No (4/393) (2/2)
Ovary 2 No (1/562) (1/2)
Oviduct 2 No (2/562) (1/2)
Pancreas 2 No (6/562)
Peripheral nervous system 2 No (3/562) (2/2)
Peyer's patch 2 No (1/393)
Pituitary gland 2 No (1/562) (1/2)
Prostate gland 2 No (5/562)
Skeletal muscle 2 No
Skin 2 No (1/562)
Small intestine 2 No (11/562) (2/2)
Spinal cord 2 No (3/562) (2/2)
Spleen 2 No (4/562)
Stomach 2 No (9/562) (2/2)
Striatum 2 No (4/562) (2/2)
Submandibular gland 2 No (1/104) (2/2)
Testis 2 No (4/562) (1/2)
Thalamus 2 No (2/2)
Thymus 2 No
Thyroid gland 2 No (16/562)
Trachea 2 No (3/562) (2/2)
Urinary bladder 2 No (2/2)
Uterus 2 No (2/562) (1/2)
Vascular system 2 No (1/393) (2/2)
Vesicular gland 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse
    respiratory system
    endocrine system
    digestive system
    cardiovascular system
    nervous system
    set of connective tissues
    sensory organ
    reproductive system
    exocrine system
    trunk
    urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2 (6/482)
Dorsal root ganglion 1 (1/45)
Ear 2 (1/482)
Embryo 2 (1/482)
Eye 2 (1/482)
Foot 2 (1/482)
Forebrain 2 (1/482)
Forelimb 2 (1/482)
Fronto-nasal process 1 (1/46)
Hand 2 (1/482)
Head 2 (5/482)
Heart 2 (1/482)
Hindbrain 2 (6/482)
Hindlimb 2 (1/482)
Liver 2 (1/482)
Lung 2 (1/482)
Mandibular process 2 (1/482)
Maxillary process 2 (1/482)
Midbrain 2 (1/482)
Nose 1 (1/47)
Oral cavity 2 (1/482)
Skin 2 (1/482)
Spinal cord 1 (1/46)
Tail 2 (1/482)
Tail somite 2 (1/482)


Associated Images

Associated Images
  • X-ray: XRay Images Dorso Ventral
    13 Images
  • Electroretinography 2: Rod and cone PDF
    4 Images
  • X-ray: XRay Images Lateral Orientation
    13 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    13 Images
  • X-ray: XRay Images Forepaw
    13 Images
  • X-ray: XRay Images Skull Lateral Orientation
    13 Images
  • Eye Morphology: Images Slit Lamp
    1 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Tmem14atm2a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Tmem14atm2b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene