Gene: Exoc3l2

Order

Name exocyst complex component 3-like 2

Synonyms
  • 4933417E01Rik
  • Gm19857

Status ES CellsMice
tm1a
Mice
tm1b
Mice
em1
phenotype data available

Links MGI:1921713    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable     Homozygous - Lethal

Phenotype associations for Exoc3l2

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Exoc3l2 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
preweaning lethality, complete penetrance Exoc3l2tm1b(KOMP)Wtsi HOM Female Male n/a 0.0
abnormal cranium morphology Exoc3l2tm1a(KOMP)Wtsi HOM Female postnatal 1.33E-7
abnormal tooth morphology Exoc3l2tm1a(KOMP)Wtsi HOM Female postnatal 2.15E-6
abnormal snout morphology Exoc3l2tm1a(KOMP)Wtsi HOM Female postnatal 6.65E-6
increased circulating iron level Exoc3l2tm1b(KOMP)Wtsi HET Female postnatal 3.51E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 6 No
Aorta 6 No
Blood vessel 6 No
Bone 6 No
Brain 6 No
Brainstem 6 No
Brown adipose tissue 6 No
Cartilage tissue 6 No
Cerebellum 6 No
Cerebral cortex 6 No
Eye 6 No
Gall bladder 6 No
Heart 6 No
Hippocampus 6 No
Hypothalamus 6 No
Kidney 6 No (18/584) (4/6)
Large intestine 6 No (10/584)
Liver 6 No
Lower urinary tract 6 No
Lung 6 No
Lymph node 6 No
Mammary gland 6 No
Esophagus 6 No
Olfactory lobe 6 No
Ovary 6 No (1/584)
Oviduct 6 No
Pancreas 6 No (5/584)
Parathyroid gland 6 No
Peripheral nervous system 6 No
Peyer's patch 6 No
Pituitary gland 6 No
Prostate gland 6 No (12/584)
Skeletal muscle tissue 6 No
Skin 6 No
Small intestine 6 No (9/584)
Spinal cord 6 No
Spleen 6 No (2/584)
Stomach 6 No (12/584)
Striatum 6 No
Testis 6 No (2/584) (1/6)
Thymus 6 No
Thyroid gland 6 No (15/584)
Trachea 6 No
Uterus 6 No
White adipose tissue 6 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse reproductive system trunk urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Secondary lacZ Expression Data
postnatal mouse (2)
  • Exoc3l2tm1b(KOMP)Wtsi
    testis, HET, Male, WTSI
  • Exoc3l2tm1b(KOMP)Wtsi
    kidney, HET, Female, WTSI
trunk (2)
  • Exoc3l2tm1b(KOMP)Wtsi
    testis, HET, Male, WTSI
  • Exoc3l2tm1b(KOMP)Wtsi
    kidney, HET, Female, WTSI
reproductive system (1)
  • Exoc3l2tm1b(KOMP)Wtsi
    testis, HET, Male, WTSI
urinary system (1)
  • Exoc3l2tm1b(KOMP)Wtsi
    kidney, HET, Female, WTSI

Associated Images

Associated Images
  • X-ray: XRay Images Forepaw
    26 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    26 Images
  • X-ray: XRay Images Lateral Orientation
    52 Images
  • X-ray: XRay Images Dorso Ventral
    78 Images
  • X-ray: XRay Images Skull Lateral Orientation
    26 Images
  • Eye Morphology: Images Slit Lamp
    2 Images
  • Anti-nuclear antibody assay
    6 Images
  • DSS Histology
    8 Images
Legacy Phenotype Associated Images
Xray (130)
  • Exoc3l2tm1a(KOMP)Wtsi
    HOM, Male, WTSI
  • Exoc3l2tm1a(KOMP)Wtsi
    HOM, Male, WTSI
  • Exoc3l2tm1a(KOMP)Wtsi
    HOM, Male, WTSI
  • Exoc3l2tm1b(KOMP)Wtsi
    HET, Female, WTSI
  • Exoc3l2tm1b(KOMP)Wtsi
    HET, Female, WTSI

show all 130 images

Embryo Dysmorphology (2)
  • Exoc3l2tm1b(KOMP)Wtsi
    HOM, Female, WTSI
  • Exoc3l2tm1b(KOMP)Wtsi
    HOM, Female, WTSI
Eye Morphology (2)
  • Exoc3l2tm1a(KOMP)Wtsi
    cornea/lens fusion, HOM, Female, WTSI
  • Exoc3l2tm1a(KOMP)Wtsi
    left eye, HOM, Female, WTSI
Skin Histopathology (1)
  • Exoc3l2tm1a(KOMP)Wtsi
    back skin, HOM, Female, WTSI

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Exoc3l2tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Exoc3l2tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Exoc3l2em1(IMPC)J Exon Deletion
Vector
Gene