Gene: Chic2
Name cysteine-rich hydrophobic domain 2
Synonyms
- 1700081B18Rik
- BTL
- 4930502K01Rik
Status
ES CellsMice
tm1aMice
tm1bphenotype data available
Links MGI:1921527 Ensembl Gene Ensembl Orthologs
Viability Homozygous - Subviable
Phenotype associations for Chic2
All Phenotypes Summary
Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Chic2 data for that phenotype.
Embryo Data:
3D Embryo Imaging
Significant Phenotypes
| System | Phenotype | Allele | Zyg | Sex | Life Stage | P Value | Data |
|---|---|---|---|---|---|---|---|
|
|
preweaning lethality, incomplete penetrance | Chic2tm1b(EUCOMM)Wtsi | HOM |
|
n/a | 0.0 | |
|
|
abnormal coat/hair pigmentation | Chic2tm1b(EUCOMM)Wtsi | HET |
|
postnatal | 3.63E-8 | |
|
|
iris synechia | Chic2tm1b(EUCOMM)Wtsi | HET |
|
postnatal | 2.78E-5 |
Expression
IMPC lacZ Expression Data
Show expression table
Expression No Expression No Tissue Available Ambiguous
Show Wildtype Expression
| Anatomy | #HET Specimens | HOM Images? | WT Expr | Mutant Expr | Images |
|---|---|---|---|---|---|
| Adrenal gland | 2 | No | (5/393) | (2/2) | |
| Aorta | 2 | No | (1/562) | (2/2) | |
| Bone | 2 | No | (1/539) | (2/2) | |
| Brain | 2 | No | (6/562) | (2/2) | |
| Brainstem | 2 | No | (4/562) | (2/2) | |
| Brown adipose tissue | 2 | No | (2/2) | ||
| Cartilage tissue | 2 | No | (1/562) | (2/2) | |
| Cerebellum | 2 | No | (4/562) | (2/2) | |
| Cerebral cortex | 2 | No | (5/562) | (2/2) | |
| Esophagus | 2 | No | (2/393) | (2/2) | |
| Eye | 2 | No | (1/562) | (2/2) | |
| Gall bladder | 2 | No | (2/2) | ||
| Heart | 2 | No | (3/562) | (2/2) | |
| Hippocampus | 2 | No | (5/562) | (2/2) | |
| Hypothalamus | 2 | No | (4/562) | (2/2) | |
| Kidney | 2 | No | (20/562) | (2/2) | |
| Large intestine | 2 | No | (12/562) | (2/2) | |
| Liver | 2 | No | (2/2) | ||
| Lower urinary tract | 2 | No | (3/562) | (2/2) | |
| Lung | 2 | No | (3/562) | (2/2) | |
| Lymph node | 2 | No | (1/562) | (1/2) | |
| Mammary gland | 2 | No | (1/2) | ||
| Olfactory lobe | 2 | No | (4/393) | (2/2) | |
| Oral epithelium | 2 | No | (2/2) | ||
| Ovary | 2 | No | (1/562) | (1/2) | |
| Oviduct | 2 | No | (2/562) | (1/2) | |
| Pancreas | 2 | No | (6/562) | (2/2) | |
| Parathyroid gland | 2 | No | (2/540) | (2/2) | |
| Peripheral nervous system | 2 | No | (3/562) | (2/2) | |
| Peyer's patch | 2 | No | (1/393) | ||
| Pituitary gland | 2 | No | (1/562) | (2/2) | |
| Prostate gland | 2 | No | (5/562) | (1/2) | |
| Skeletal muscle | 2 | No | |||
| Skin | 2 | No | (1/562) | (2/2) | |
| Small intestine | 2 | No | (11/562) | (2/2) | |
| Spinal cord | 2 | No | (3/562) | (2/2) | |
| Spleen | 2 | No | (4/562) | ||
| Stomach | 2 | No | (9/562) | (2/2) | |
| Striatum | 2 | No | (4/562) | (2/2) | |
| Testis | 2 | No | (4/562) | (1/2) | |
| Thymus | 2 | No | |||
| Thyroid gland | 2 | No | (16/562) | (1/2) | |
| Trachea | 2 | No | (3/562) | (2/2) | |
| Uterus | 2 | No | (2/562) | (1/2) | |
| Vascular system | 2 | No | (1/393) | (2/2) | |
| White adipose tissue | 2 | No |
Expression in Anatomogram
Tissues/organs lacZ+ expression
No expression image was found for this adult tab
Expression No Expression No Tissue Available Ambiguous
| Anatomy | #HET Specimens | WT Expr | Mutant Expr | Images |
|---|---|---|---|---|
| Brain | 2 | (6/440) | (4/4) | |
| Ear | 2 | (1/440) | (1/4) | |
| Embryo | 2 | (1/440) | (4/4) | |
| Eye | 2 | (1/440) | (4/4) | |
| Foot | 2 | (1/4) | ||
| Forebrain | 2 | (1/440) | (4/4) | |
| Forelimb | 2 | (1/440) | (3/4) | |
| Hand | 2 | (1/4) | ||
| Head | 2 | (5/440) | (4/4) | |
| Heart | 2 | (1/440) | (2/4) | |
| Hindbrain | 2 | (5/440) | (4/4) | |
| Hindlimb | 2 | (1/440) | (3/4) | |
| Liver | 2 | (1/440) | (1/4) | |
| Lung | 2 | (1/440) | (2/4) | |
| Mandibular process | 2 | (1/440) | (2/4) | |
| Maxillary process | 2 | (1/440) | (1/4) | |
| Midbrain | 2 | (1/440) | (4/4) | |
| Oral cavity | 2 | (1/440) | (1/4) | |
| Skin | 2 | (1/440) | ||
| Tail | 2 | (1/440) | (3/4) | |
| Tail somite | 2 | (1/440) | (1/4) |
Associated Images
Associated Images
-
X-ray: XRay Images Dorso Ventral
11 Images
-
X-ray: XRay Images Skull Dorso Ventral Orientation
11 Images
-
X-ray: XRay Images Lateral Orientation
11 Images
-
Embryo LacZ: LacZ images wholemount
8 Images
-
Echo: M-Mode Images
36 Images
-
Adult LacZ: LacZ Images Wholemount
26 Images
Order Mouse and ES Cells
| Targeting Detail | Product Ordering | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MGI Allele | Allele Type | Type Map Seq | Vector | ES Cell | Mouse | Tissue Enquiry | ||||||
| Chic2tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) |
|
||||||||||
| Chic2tm1b(EUCOMM)Wtsi | Reporter-tagged deletion allele (post-Cre) |
|
||||||||||
| Chic2tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) |
|
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