Gene: Rap2b

Order

Name RAP2B, member of RAS oncogene family

Synonyms 4021402C18Rik

Status ES CellsMice
tm1.1
Mice
tm1
phenotype data available

Links MGI:1921262    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Rap2b

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Rap2b data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal behavior Rap2btm1.1(KOMP)Vlcg HOM Female Male postnatal 3.39E-8
hyperactivity Rap2btm1.1(KOMP)Vlcg HOM Female Male postnatal 1.03E-7
abnormal behavioral response to light Rap2btm1.1(KOMP)Vlcg HOM Female Male postnatal 4.29E-5
abnormal sleep behavior Rap2btm1.1(KOMP)Vlcg HOM Female Male postnatal 7.19E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415) (2/2)
Aorta 2 No (2/2)
Brain 2 No (2/2)
Brainstem 2 No (2/2)
Brown adipose tissue 2 No
Cartilage tissue 2 No (2/2)
Cerebellum 2 No (2/2)
Cerebral cortex 2 No (2/2)
Epididymis 2 No (18/134) (1/2)
Esophagus 2 No (7/415) (2/2)
Eye 2 No (2/2)
Heart 2 No (2/2)
Hippocampus 2 No (2/2)
Hypothalamus 2 No (2/2)
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584) (2/2)
Liver 2 No
Lower urinary tract 2 No
Lung 2 No (2/2)
Lymph node 2 No (2/2)
Mammary gland 2 No (1/2)
Midbrain 2 No (2/2)
Olfactory lobe 2 No (2/2)
Ovary 2 No (1/584) (1/2)
Oviduct 2 No (1/2)
Pancreas 2 No (5/584) (2/2)
Peripheral nervous system 2 No (2/2)
Peyer's patch 2 No (2/2)
Pituitary gland 2 No (2/2)
Prostate gland 2 No (12/584)
Skeletal muscle 2 No
Skin 2 No (2/2)
Small intestine 2 No (9/584) (2/2)
Spinal cord 2 No (2/2)
Spleen 2 No (2/584) (2/2)
Stomach 2 No (12/584) (2/2)
Striatum 2 No (2/2)
Submandibular gland 2 No (2/132) (2/2)
Testis 2 No (2/584) (1/2)
Thalamus 2 No (2/2)
Thymus 2 No (2/2)
Thyroid gland 2 No (15/584) (2/2)
Trachea 2 No (2/2)
Urinary bladder 2 No (2/2)
Uterus 2 No (1/2)
Vascular system 2 No (2/2)
Vesicular gland 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system respiratory system digestive system cardiovascular system set of connective tissues reproductive system trunk postnatal mouse nervous system sensory organ immune system exocrine system integumental system urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2 (6/485) (2/3)
Dorsal root ganglion 2 (1/47) Image Only
Ear 2 (1/485) Image Only
Embryo 2 (1/485) (2/3)
Eye 2 (1/485) (2/3)
Foot 2 (1/485) (2/3)
Forebrain 2 (1/485) (2/3)
Forelimb 2 (1/485) (2/3)
Fronto-nasal process 2 (1/48) Image Only
Hand 2 (1/485) (2/3)
Head 2 (5/485) (2/3)
Heart 2 (1/485) (2/3)
Hindbrain 2 (6/485) (2/3)
Hindlimb 2 (1/485) (2/3)
Liver 2 (1/485) Image Only
Lung 2 (1/485) Image Only
Mandibular process 2 (1/485) (2/3)
Maxillary process 2 (1/485) (2/3)
Midbrain 2 (1/485) (2/3)
Nose 2 (1/51) (2/3)
Oral cavity 2 (1/485) Image Only
Skin 2 (1/485) (2/3)
Spinal cord 2 (1/50) (2/3)
Tail 2 (1/485) (2/3)
Tail somite 2 (1/485) (2/3)


Associated Images

Associated Images
  • X-ray: XRay Images Lateral Orientation
    11 Images
  • X-ray: XRay Images Forepaw
    11 Images
  • Sleep Wake: Wake state (bmp file)
    11 Images
  • Embryo LacZ: LacZ images wholemount
    12 Images
  • X-ray: XRay Images Dorso Ventral
    11 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    11 Images
  • X-ray: XRay Images Skull Lateral Orientation
    11 Images
  • Electroretinography 2: Rod and cone PDF
    4 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Rap2btm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette)
Vector
Gene
Rap2btm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene