Gene: Tbkbp1

Order

Name TBK1 binding protein 1

Synonyms 3110043L15Rik

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:1920424    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Tbkbp1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Tbkbp1 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
increased lymphocyte cell number Tbkbp1tm1b(EUCOMM)Wtsi HOM Female Male postnatal 3.17E-5
increased leukocyte cell number Tbkbp1tm1b(EUCOMM)Wtsi HOM Female Male postnatal 4.27E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (5/393)
Aorta 2 No (1/562)
Bone 2 No (1/539)
Brain 2 No (6/562) (2/2)
Brainstem 2 No (4/562) (2/2)
Brown adipose tissue 2 No (2/2)
Cartilage tissue 2 No (1/562)
Cerebellum 2 No (4/562) (2/2)
Cerebral cortex 2 No (5/562) (2/2)
Esophagus 2 No (2/393)
Eye 2 No (1/562)
Gall bladder 2 No
Heart 2 No (3/562)
Hippocampus 2 No (5/562) (2/2)
Hypothalamus 2 No (4/562) (2/2)
Kidney 2 No (20/562) (1/2)
Large intestine 2 No (12/562)
Liver 2 No
Lower urinary tract 2 No (3/562) (2/2)
Lung 2 No (3/562)
Lymph node 2 No (1/562)
Mammary gland 2 No
Olfactory lobe 2 No (4/393) (2/2)
Oral epithelium 2 No
Ovary 2 No (1/562)
Oviduct 2 No (2/562) (1/2)
Pancreas 2 No (6/562)
Parathyroid gland 2 No (2/540)
Peripheral nervous system 2 No (3/562) (2/2)
Peyer's patch 2 No (1/393)
Pituitary gland 2 No (1/562)
Prostate gland 2 No (5/562)
Skeletal muscle 2 No
Skin 2 No (1/562)
Small intestine 2 No (11/562)
Spinal cord 2 No (3/562) (1/2)
Spleen 2 No (4/562)
Stomach 2 No (9/562)
Striatum 2 No (4/562)
Testis 2 No (4/562) (1/2)
Thymus 2 No
Thyroid gland 2 No (16/562)
Trachea 2 No (3/562)
Uterus 2 No (2/562) (1/2)
Vascular system 2 No (1/393)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse
    nervous system
    set of connective tissues
    reproductive system
    adipose tissue
    trunk
    urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2 (6/482) (4/4)
Ear 2 (1/482) (1/4)
Embryo 2 (1/482) (4/4)
Eye 2 (1/482) (2/4)
Foot 2 (1/482) (1/4)
Forebrain 2 (1/482) (3/4)
Forelimb 2 (1/482) (3/4)
Hand 2 (1/482) (1/4)
Head 2 (5/482) (4/4)
Heart 2 (1/482) (2/4)
Hindbrain 2 (6/482) (2/4)
Hindlimb 2 (1/482) (3/4)
Liver 2 (1/482) (1/4)
Lung 2 (1/482) (2/4)
Mandibular process 2 (1/482) (1/4)
Maxillary process 2 (1/482) (1/4)
Midbrain 2 (1/482) (2/4)
Oral cavity 2 (1/482) (1/4)
Skin 2 (1/482) (2/4)
Tail 2 (1/482) (2/4)
Tail somite 2 (1/482) (1/4)


Associated Images

Associated Images
  • Echo: M-Mode Images
    32 Images
  • Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
    2 Images
  • X-ray: XRay Images Dorso Ventral
    13 Images
  • X-ray: XRay Images Lateral Orientation
    12 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    12 Images
  • Adult LacZ: LacZ Images Wholemount
    11 Images
  • Embryo LacZ: LacZ images wholemount
    8 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Tbkbp1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Tbkbp1tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene