Gene: Ddx41

Order

Name DEAD (Asp-Glu-Ala-Asp) box polypeptide 41

Synonyms 2900024F02Rik

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:1920185    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Ddx41

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Ddx41 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
embryonic lethality prior to organogenesis Ddx41tm1b(KOMP)Wtsi HOM Female Male embryonic day 9.5 0.0
embryonic lethality prior to tooth bud stage Ddx41tm1b(KOMP)Wtsi HOM Female Male embryonic day 12.5 0.0
preweaning lethality, complete penetrance Ddx41tm1b(KOMP)Wtsi HOM Female Male n/a 0.0

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Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415) (1/2)
Aorta 2 No
Brain 2 No (2/2)
Brainstem 2 No
Cartilage tissue 2 No
Cerebellum 2 No
Cerebral cortex 2 No (1/2)
Esophagus 2 No (7/415)
Eye 2 No
Heart 2 No
Hippocampus 2 No (2/2)
Hypothalamus 2 No
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584) (1/2)
Liver 2 No (1/2)
Lower urinary tract 2 No
Lung 2 No
Lymph node 2 No
Mammary gland 2 No
Olfactory lobe 2 No
Ovary 2 No (1/584) (1/2)
Oviduct 2 No (1/2)
Pancreas 2 No (5/584)
Peripheral nervous system 2 No
Peyer's patch 2 No
Pituitary gland 2 No
Prostate gland 2 No (12/584) (1/2)
Skeletal muscle 2 No
Skin 2 No
Small intestine 2 No (9/584) (1/2)
Spinal cord 2 No
Spleen 2 No (2/584)
Stomach 2 No (12/584)
Striatum 2 No
Testis 2 No (2/584) (1/2)
Thymus 2 No
Thyroid gland 2 No (15/584) (1/2)
Trachea 2 No
Uterus 2 No
Vascular system 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse
    endocrine system digestive system
    nervous system
    reproductive system exocrine system trunk urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2 (1/51)
Brain 5 (6/485)
Central nervous system ganglion 2 (1/51)
Ear 5 (1/485)
Embryo 5 (1/485) (2/5)
Eye 5 (1/485) (2/5)
Foot 5 (1/485)
Forebrain 5 (1/485)
Forelimb 5 (1/485)
Gut 2 (1/50)
Hand 5 (1/485)
Head 5 (5/485)
Heart 5 (1/485) (2/5)
Hindbrain 5 (6/485)
Hindlimb 5 (1/485)
Liver 5 (1/485)
Lung 5 (1/485) (2/5)
Mandibular process 5 (1/485)
Maxillary process 5 (1/485)
Midbrain 5 (1/485)
Nose 2 (1/51)
Oral cavity 5 (1/485) Image Only
Skeleton 2 (1/51)
Skin 5 (1/485)
Spinal cord 2 (1/50)
Tail 5 (1/485)
Tail somite 5 (1/485)
Trachea 2 (1/50)
Urinary system 2 (1/50) (2/2)


Associated Images

Associated Images
  • Gross Pathology and Tissue Collection
    8 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    14 Images
  • X-ray: XRay Images Skull Lateral Orientation
    14 Images
  • X-ray: XRay Images Lateral Orientation
    14 Images
  • X-ray: XRay Images Dorso Ventral
    14 Images
  • Embryo LacZ: LacZ images wholemount
    12 Images
  • Eye Morphology: Images Ophthalmoscopy
    2 Images
  • Adult LacZ: LacZ Images Section
    5 Images

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Ddx41tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Ddx41tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene