Gene: Slc38a10

Order

Name solute carrier family 38, member 10

Synonyms 1810073N04Rik

Status ES CellsMice
tm1a
Mice
tm2a
phenotype data available

Links MGI:1919305    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Slc38a10

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Slc38a10 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal eye morphology Slc38a10tm2a(EUCOMM)Wtsi HOM Female Male postnatal 0.0
abnormal retina morphology Slc38a10tm2a(EUCOMM)Wtsi HOM Female Male postnatal 0.0
decreased circulating alkaline phosphatase level Slc38a10tm2a(EUCOMM)Wtsi HOM Female Male postnatal 1.98E-19
decreased body weight Slc38a10tm1a(EUCOMM)Wtsi HOM Female Male postnatal 1.23E-15
decreased bone mineral content Slc38a10tm1a(EUCOMM)Wtsi HOM Female Male postnatal 7.87E-13
decreased circulating alkaline phosphatase level Slc38a10tm1a(EUCOMM)Wtsi HOM Female Male postnatal 3.3E-12
decreased total body fat amount Slc38a10tm1a(EUCOMM)Wtsi HOM Female Male postnatal 5.38E-12
decreased erythrocyte cell number Slc38a10tm2a(EUCOMM)Wtsi HOM Female Male postnatal 2.96E-11
decreased hemoglobin content Slc38a10tm2a(EUCOMM)Wtsi HOM Female Male postnatal 1.1E-10
decreased lean body mass Slc38a10tm2a(EUCOMM)Wtsi HOM Female Male postnatal 3.62E-9
abnormal response to tactile stimuli Slc38a10tm2a(EUCOMM)Wtsi HOM Male postnatal 4.35E-9
decreased body weight Slc38a10tm2a(EUCOMM)Wtsi HOM Female Male postnatal 3.82E-8
decreased circulating triglyceride level Slc38a10tm2a(EUCOMM)Wtsi HOM Male postnatal 4.63E-8
abnormal bone structure Slc38a10tm1a(EUCOMM)Wtsi HOM Female Male postnatal 6.6E-8
decreased hematocrit Slc38a10tm2a(EUCOMM)Wtsi HOM Female Male postnatal 1.19E-7
decreased lean body mass Slc38a10tm1a(EUCOMM)Wtsi HOM Female Male postnatal 2.68E-7
increased circulating potassium level Slc38a10tm2a(EUCOMM)Wtsi HOM Female postnatal 3.29E-7
increased circulating iron level Slc38a10tm1a(EUCOMM)Wtsi HOM Female Male postnatal 5.85E-7
increased mean corpuscular volume Slc38a10tm2a(EUCOMM)Wtsi HOM Female Male postnatal 1.03E-6
decreased body length Slc38a10tm1a(EUCOMM)Wtsi HOM Female Male postnatal 1.34E-6
decreased bone mineral density Slc38a10tm1a(EUCOMM)Wtsi HOM Female Male postnatal 1.53E-6
decreased circulating serum albumin level Slc38a10tm2a(EUCOMM)Wtsi HOM Female Male postnatal 2.61E-6
decreased circulating calcium level Slc38a10tm2a(EUCOMM)Wtsi HOM Female Male postnatal 2.66E-6
decreased grip strength Slc38a10tm2a(EUCOMM)Wtsi HOM Female Male postnatal 2.86E-6
decreased circulating total protein level Slc38a10tm2a(EUCOMM)Wtsi HOM Female Male postnatal 3.6E-6
abnormal bone mineralization Slc38a10tm2a(EUCOMM)Wtsi HOM Female Male postnatal 8.48E-6
decreased circulating calcium level Slc38a10tm1a(EUCOMM)Wtsi HOM Female Male postnatal 8.49E-6
abnormal cranium morphology Slc38a10tm1a(EUCOMM)Wtsi HOM Male postnatal 8.53E-6
increased mean platelet volume Slc38a10tm1a(EUCOMM)Wtsi HOM Female Male postnatal 8.79E-6
increased circulating triglyceride level Slc38a10tm2a(EUCOMM)Wtsi HOM Female postnatal 1.42E-5
decreased circulating free fatty acid level Slc38a10tm2a(EUCOMM)Wtsi HOM Female Male postnatal 2.84E-5
decreased heart weight Slc38a10tm1a(EUCOMM)Wtsi HOM Female Male postnatal 2.98E-5
decreased NK cell number Slc38a10tm1a(EUCOMM)Wtsi HOM Female Male postnatal 2.99E-5
decreased caudal vertebrae number Slc38a10tm1a(EUCOMM)Wtsi HOM Female Male postnatal 3.07E-5
increased mean corpuscular hemoglobin concentration Slc38a10tm2a(EUCOMM)Wtsi HOM Female Male postnatal 3.51E-5
increased circulating glycerol level Slc38a10tm1a(EUCOMM)Wtsi HOM Female Male postnatal 3.51E-5
increased circulating HDL cholesterol level Slc38a10tm1a(EUCOMM)Wtsi HOM Female Male postnatal 3.83E-5
increased circulating creatinine level Slc38a10tm1a(EUCOMM)Wtsi HOM Male postnatal 3.97E-5
increased circulating phosphate level Slc38a10tm2a(EUCOMM)Wtsi HOM Female Male postnatal 6.6E-5
decreased bone mineral density Slc38a10tm2a(EUCOMM)Wtsi HOM Female Male postnatal 6.81E-5
decreased circulating sodium level Slc38a10tm2a(EUCOMM)Wtsi HOM Female Male postnatal 6.85E-5
decreased circulating amylase level Slc38a10tm2a(EUCOMM)Wtsi HOM Female Male postnatal 7.22E-5
abnormal maxilla morphology Slc38a10tm1a(EUCOMM)Wtsi HOM Male postnatal 7.77E-5
abnormal startle reflex Slc38a10tm2a(EUCOMM)Wtsi HOM Male postnatal 7.94E-5
short tibia Slc38a10tm2a(EUCOMM)Wtsi HOM Female Male postnatal 8.84E-5
decreased circulating total protein level Slc38a10tm1a(EUCOMM)Wtsi HOM Female Male postnatal 8.97E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 7 No (7/7)
Aorta 7 No (1/562)
Blood vessel 7 No
Bone 7 No (1/539) (6/7)
Brain 7 No (6/562) (7/7)
Brainstem 7 No (4/562)
Brown adipose tissue 7 No
Cartilage tissue 7 No (1/562) (7/7)
Cerebellum 7 No (4/562)
Cerebral cortex 7 No (5/562)
Eye 7 No (1/562) (1/7)
Gall bladder 7 No
Heart 7 No (3/562) (6/7)
Hippocampus 7 No (5/562)
Hypothalamus 7 No (4/562)
Kidney 7 No (20/562) (7/7)
Large intestine 7 No (12/562) (2/7)
Liver 7 No (1/7)
Lower urinary tract 7 No (3/562) (1/7)
Lung 7 No (3/562) (5/7)
Lymph node 7 No (1/562) (1/7)
Mammary gland 7 No
Esophagus 7 No
Olfactory lobe 7 No
Ovary 7 No (1/562) (4/7)
Oviduct 7 No (2/562) (4/7)
Pancreas 7 No (6/562) (7/7)
Parathyroid gland 7 No (2/540) (5/7)
Peripheral nervous system 7 No (3/562) (7/7)
Peyer's patch 7 No
Pituitary gland 7 No (1/562) (6/7)
Prostate gland 7 No (5/562) (2/7)
Skeletal muscle tissue 7 No (1/7)
Skin 7 No (1/562) (7/7)
Small intestine 7 No (11/562) (5/7)
Spinal cord 7 No (3/562) (7/7)
Spleen 7 No (4/562) (2/7)
Stomach 7 No (9/562)
Striatum 7 No (4/562)
Testis 7 No (4/562) (3/7)
Thymus 7 No (5/7)
Thyroid gland 7 No (16/562) (3/7)
Trachea 7 No (3/562) (6/7)
Uterus 7 No (2/562) (4/7)
White adipose tissue 7 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system respiratory system digestive system cardiovascular system set of connective tissues reproductive system musculoskeletal system trunk postnatal mouse nervous system sensory organ immune system exocrine system integumental system urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Secondary lacZ Expression Data
trunk (15)
  • Slc38a10tm1a(EUCOMM)Wtsi
    LUNG, LUNG, HET, Male, WTSI
  • Slc38a10tm1a(EUCOMM)Wtsi
    LOWER URINARY TRACT, URINARY BLADDER, HET, Male, WTSI
  • Slc38a10tm1a(EUCOMM)Wtsi
    TESTIS, HET, Male, WTSI
  • Slc38a10tm1a(EUCOMM)Wtsi
    TRACHEA, HET, Female, WTSI
  • Slc38a10tm1a(EUCOMM)Wtsi
    LARGE INTESTINE, HET, Female, WTSI

show all 15 images

nervous system (4)
  • Slc38a10tm1a(EUCOMM)Wtsi
    BRAIN, HET, Female, WTSI
  • Slc38a10tm1a(EUCOMM)Wtsi
    BRAIN, HET, Female, WTSI
  • Slc38a10tm1a(EUCOMM)Wtsi
    PITUITARY GLAND, PERIPHERAL NERVOUS SYSTEM, HET, Female, WTSI
  • Slc38a10tm1a(EUCOMM)Wtsi
    SPINAL CORD, HET, Female, WTSI
digestive system (3)
  • Slc38a10tm1a(EUCOMM)Wtsi
    LARGE INTESTINE, HET, Female, WTSI
  • Slc38a10tm1a(EUCOMM)Wtsi
    LIVER, HET, Male, WTSI
  • Slc38a10tm1a(EUCOMM)Wtsi
    SMALL INTESTINE, HET, Female, WTSI
immune system (3)
  • Slc38a10tm1a(EUCOMM)Wtsi
    THYMUS, HET, Male, WTSI
  • Slc38a10tm1a(EUCOMM)Wtsi
    SPLEEN, HET, Male, WTSI
  • Slc38a10tm1a(EUCOMM)Wtsi
    LYMPH NODE, HET, Female, WTSI
urinary system (3)
  • Slc38a10tm1a(EUCOMM)Wtsi
    LOWER URINARY TRACT, URINARY BLADDER, HET, Male, WTSI
  • Slc38a10tm1a(EUCOMM)Wtsi
    LOWER URINARY TRACT, HET, Male, WTSI
  • Slc38a10tm1a(EUCOMM)Wtsi
    KIDNEY, HET, Female, WTSI
musculoskeletal system (2)
  • Slc38a10tm1a(EUCOMM)Wtsi
    BONE, HET, Female, WTSI
  • Slc38a10tm1a(EUCOMM)Wtsi
    SKELETAL MUSCLE TISSUE, HET, Male, WTSI
reproductive system (2)
  • Slc38a10tm1a(EUCOMM)Wtsi
    TESTIS, HET, Male, WTSI
  • Slc38a10tm1a(EUCOMM)Wtsi
    UTERUS, HET, Female, WTSI
respiratory system (2)
  • Slc38a10tm1a(EUCOMM)Wtsi
    LUNG, LUNG, HET, Male, WTSI
  • Slc38a10tm1a(EUCOMM)Wtsi
    TRACHEA, HET, Female, WTSI
cardiovascular system (1)
  • Slc38a10tm1a(EUCOMM)Wtsi
    HEART, HET, Female, WTSI
endocrine system (1)
  • Slc38a10tm1a(EUCOMM)Wtsi
    ADRENAL GLAND, HET, Female, WTSI
integumental system (1)
  • Slc38a10tm1a(EUCOMM)Wtsi
    SKIN, HET, Male, WTSI
sensory organ (1)
  • Slc38a10tm1a(EUCOMM)Wtsi
    EYE, HET, Male, WTSI

Associated Images

Associated Images
  • X-ray: XRay Images Dorso Ventral
    42 Images
  • X-ray: XRay Images Lateral Orientation
    28 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    14 Images
  • X-ray: XRay Images Skull Lateral Orientation
    14 Images
  • X-ray: XRay Images Forepaw
    14 Images
Legacy Phenotype Associated Images
Xray (98)
  • Slc38a10tm1a(EUCOMM)Wtsi
    HOM, Male, WTSI
  • Slc38a10tm1a(EUCOMM)Wtsi
    HOM, Male, WTSI
  • Slc38a10tm1a(EUCOMM)Wtsi
    HOM, Male, WTSI
  • Slc38a10tm1a(EUCOMM)Wtsi
    HOM, Male, WTSI
  • Slc38a10tm1a(EUCOMM)Wtsi
    HOM, Male, WTSI

show all 98 images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Slc38a10tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Slc38a10tm2a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Slc38a10tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene
Slc38a10tm3a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene