Gene: Cers5

Order

Name ceramide synthase 5

Synonyms
  • Trh4
  • Lass5
  • 2310081H14Rik
  • CerS5

Status ES CellsMice
tm2b
Mice
tm2a
phenotype data available

Links MGI:1919199    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Cers5

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Cers5 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
decreased lean body mass Cers5tm2b(KOMP)Mbp HOM Male postnatal 1.86E-10
decreased bone mineral content Cers5tm2b(KOMP)Mbp HOM Female postnatal 6.86E-7
increased circulating sodium level Cers5tm2b(KOMP)Mbp HOM Female Male postnatal 4.5E-6
abnormal motor coordination/balance Cers5tm2b(KOMP)Mbp HOM Female Male postnatal 3.36E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415) (2/2)
Aorta 2 No (2/2)
Brain 2 No (2/2)
Brainstem 2 No (2/2)
Brown adipose tissue 2 No
Cartilage tissue 2 No (2/2)
Cerebellum 2 No (2/2)
Cerebral cortex 2 No (2/2)
Epididymis 2 No (18/134) (1/2)
Esophagus 2 No (7/415) (2/2)
Eye 2 No (2/2)
Heart 2 No (2/2)
Hippocampus 2 No (2/2)
Hypothalamus 2 No (2/2)
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584) (2/2)
Liver 2 No
Lower urinary tract 2 No
Lung 2 No (2/2)
Lymph node 2 No
Mammary gland 2 No
Midbrain 2 No (2/2)
Olfactory lobe 2 No (2/2)
Ovary 2 No (1/584) (1/2)
Oviduct 2 No (1/2)
Pancreas 2 No (5/584)
Peripheral nervous system 2 No (2/2)
Peyer's patch 2 No
Pituitary gland 2 No (2/2)
Prostate gland 2 No (12/584)
Skeletal muscle 2 No
Skin 2 No (2/2)
Small intestine 2 No (9/584) (2/2)
Spinal cord 2 No (2/2)
Spleen 2 No (2/584)
Stomach 2 No (12/584) (2/2)
Striatum 2 No (2/2)
Submandibular gland 2 No (2/132)
Testis 2 No (2/584) (1/2)
Thalamus 2 No (2/2)
Thymus 2 No
Thyroid gland 2 No (15/584)
Trachea 2 No (2/2)
Urinary bladder 2 No (2/2)
Uterus 2 No (1/2)
Vascular system 2 No (2/2)
Vesicular gland 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system postnatal mouse respiratory system digestive system cardiovascular system nervous system set of connective tissues sensory organ reproductive system integumental system trunk urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 1 (6/485) (1/2)
Ear 1 (1/485)
Embryo 1 (1/485) (1/2)
Eye 1 (1/485) (1/2)
Foot 1 (1/485) (1/2)
Forebrain 1 (1/485) Image Only
Forelimb 1 (1/485) (1/2)
Hand 1 (1/485) (1/2)
Head 1 (5/485) (1/2)
Heart 1 (1/485) (1/2)
Hindbrain 1 (6/485) (1/2)
Hindlimb 1 (1/485) (1/2)
Liver 1 (1/485) Image Only
Lung 1 (1/485) Image Only
Mandibular process 1 (1/485) (1/2)
Maxillary process 1 (1/485) (1/2)
Midbrain 1 (1/485) Image Only
Oral cavity 1 (1/485) (1/2)
Skin 1 (1/485) (1/2)
Tail 1 (1/485) (1/2)
Tail somite 1 (1/485)


Associated Images

Associated Images
  • Sleep Wake: Wake state (bmp file)
    8 Images
  • Embryo LacZ: LacZ images wholemount
    8 Images
  • Electroretinography 2: Rod and cone PDF
    4 Images
  • X-ray: XRay Images Forepaw
    9 Images
  • X-ray: XRay Images Lateral Orientation
    9 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    9 Images
  • X-ray: XRay Images Skull Lateral Orientation
    9 Images
  • X-ray: XRay Images Dorso Ventral
    9 Images
  • Combined SHIRPA and Dysmorphology
    1 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Cers5tm2b(KOMP)Mbp Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Cers5tm2a(KOMP)Mbp KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Cers5tm1a(KOMP)Mbp KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene