Gene: Gimap6

Order

Name GTPase, IMAP family member 6

Synonyms
  • 4833419H03Rik
  • Ian6

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:1918876    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Gimap6

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Gimap6 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
decreased CD4-negative NK T cell number Gimap6tm1a(KOMP)Wtsi HOM Female Male postnatal 0.0
decreased memory-marker CD4-negative NK T cell number Gimap6tm1a(KOMP)Wtsi HOM Female Male postnatal 0.0
increased memory-marker CD4-negative NK T cell number Gimap6tm1a(KOMP)Wtsi HOM Female Male postnatal 0.0
decreased mean corpuscular hemoglobin Gimap6tm1b(KOMP)Wtsi HOM Female Male postnatal 2.6E-31
decreased mean corpuscular volume Gimap6tm1b(KOMP)Wtsi HOM Female Male postnatal 1.79E-14
increased blood urea nitrogen level Gimap6tm1b(KOMP)Wtsi HOM Female Male postnatal 6.63E-11
decreased circulating amylase level Gimap6tm1a(KOMP)Wtsi HOM Female Male postnatal 1.74E-8
increased heart weight Gimap6tm1b(KOMP)Wtsi HOM Female Male postnatal 8.01E-7
decreased total body fat amount Gimap6tm1b(KOMP)Wtsi HOM Female Male postnatal 9.11E-7
decreased NK T cell number Gimap6tm1a(KOMP)Wtsi HOM Female Male postnatal 1.6E-6
increased circulating cholesterol level Gimap6tm1b(KOMP)Wtsi HOM Female Male postnatal 4.79E-6
increased fasted circulating glucose level Gimap6tm1b(KOMP)Wtsi HOM Female Male postnatal 6.04E-6
increased circulating HDL cholesterol level Gimap6tm1b(KOMP)Wtsi HOM Female postnatal 1.68E-5
increased monocyte cell number Gimap6tm1a(KOMP)Wtsi HOM Female Male postnatal 2.26E-5
decreased circulating iron level Gimap6tm1b(KOMP)Wtsi HOM Female Male postnatal 6.94E-5
decreased circulating glucose level Gimap6tm1b(KOMP)Wtsi HOM Female Male postnatal 9.46E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415)
Aorta 2 No
Brain 2 No (2/2)
Brainstem 2 No (2/2)
Brown adipose tissue 2 No
Cartilage tissue 2 No
Cerebellum 2 No
Cerebral cortex 2 No
Epididymis 2 No (18/134)
Esophagus 2 No (7/415) (2/2)
Eye 2 No
Heart 2 No (2/2)
Hippocampus 2 No
Hypothalamus 2 No
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584) (2/2)
Liver 2 No
Lower urinary tract 2 No
Lung 2 No
Lymph node 2 No (2/2)
Mammary gland 2 No
Midbrain 2 No
Olfactory lobe 2 No
Ovary 2 No (1/584) (1/2)
Oviduct 2 No (1/2)
Pancreas 2 No (5/584) (2/2)
Peripheral nervous system 2 No
Peyer's patch 2 No (2/2)
Pituitary gland 2 No (2/2)
Prostate gland 2 No (12/584)
Skeletal muscle 2 No
Skin 2 No
Small intestine 2 No (9/584) (2/2)
Spinal cord 2 No
Spleen 2 No (2/584) (2/2)
Stomach 2 No (12/584)
Striatum 2 No
Submandibular gland 2 No (2/132) (1/2)
Testis 2 No (2/584) (1/2)
Thalamus 2 No
Thymus 2 No (2/2)
Thyroid gland 2 No (15/584) (2/2)
Trachea 2 No
Urinary bladder 2 No
Uterus 2 No (1/2)
Vascular system 2 No (1/2)
Vesicular gland 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse endocrine system respiratory system digestive system cardiovascular system nervous system reproductive system immune system exocrine system trunk urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2 (6/485) (1/3)
Dorsal root ganglion 1 (1/47) Image Only
Ear 2 (1/485)
Embryo 2 (1/485) (2/3)
Eye 2 (1/485)
Foot 2 (1/485) (1/3)
Forebrain 2 (1/485)
Forelimb 2 (1/485) (1/3)
Fronto-nasal process 1 (1/48)
Gut 1 (1/50) (1/1)
Hand 2 (1/485) (1/3)
Head 2 (5/485) (2/3)
Heart 2 (1/485) (2/3)
Hindbrain 2 (6/485) (1/3)
Hindlimb 2 (1/485) (1/3)
Liver 2 (1/485)
Lung 2 (1/485)
Mandibular process 2 (1/485) (2/3)
Maxillary process 2 (1/485) (2/3)
Midbrain 2 (1/485)
Nose 2 (1/51) (2/2)
Oral cavity 2 (1/485)
Skin 2 (1/485)
Spinal cord 2 (1/50) (1/2)
Tail 2 (1/485) (2/3)
Tail somite 2 (1/485)
Thoracic vertebral cartilage condensation 1 (1/46) (1/1)


Associated Images

Associated Images
  • Spleen Immunophenotyping: Images associated with FACS analysis
    6 Images
  • X-ray: XRay Images Lateral Orientation
    38 Images
  • X-ray: XRay Images Forepaw
    24 Images
  • Embryo LacZ: LacZ images wholemount
    16 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    23 Images
  • Sleep Wake: Wake state (bmp file)
    11 Images
  • X-ray: XRay Images Skull Lateral Orientation
    24 Images
  • X-ray: XRay Images Dorso Ventral
    51 Images
  • Anti-nuclear antibody assay
    6 Images
  • DSS Histology
    8 Images
Legacy Phenotype Associated Images
Xray (69)
  • Gimap6tm1a(KOMP)Wtsi
    HOM, Female, WTSI
  • Gimap6tm1a(KOMP)Wtsi
    HOM, Female, WTSI
  • Gimap6tm1a(KOMP)Wtsi
    HOM, Female, WTSI
  • Gimap6tm1a(KOMP)Wtsi
    HOM, Female, WTSI
  • Gimap6tm1a(KOMP)Wtsi
    HOM, Female, WTSI

show all 69 images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Gimap6tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Gimap6tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Gimap6tm45182(L1L2_gt0)
Vector
Gene