Gene: Nos1ap


Name nitric oxide synthase 1 (neuronal) adaptor protein

Synonyms 6330408P19Rik

Status ES CellsMice
phenotype data available

Links MGI:1917979    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Nos1ap

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Nos1ap data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal urinary bladder morphology Nos1aptm1b(KOMP)Wtsi HOM Male postnatal 0.0
increased startle reflex Nos1aptm1b(KOMP)Wtsi HOM Female Male postnatal 5.53E-14
decreased prepulse inhibition Nos1aptm1b(KOMP)Wtsi HOM Female Male postnatal 1.13E-13
increased lean body mass Nos1aptm1b(KOMP)Wtsi HOM Female Male postnatal 3.26E-9
increased vertical activity Nos1aptm1b(KOMP)Wtsi HOM Female Male postnatal 4.94E-8
increased heart weight Nos1aptm1b(KOMP)Wtsi HOM Male postnatal 1.04E-6
increased body length Nos1aptm1b(KOMP)Wtsi HOM Female Male postnatal 1.64E-6
increased bone mineral density Nos1aptm1b(KOMP)Wtsi HOM Male postnatal 7.49E-6
hyperactivity Nos1aptm1b(KOMP)Wtsi HOM Male postnatal 2.03E-5
abnormal retinal blood vessel morphology Nos1aptm1b(KOMP)Wtsi HOM Male postnatal 2.92E-5
decreased bone mineral content Nos1aptm1b(KOMP)Wtsi HOM Female postnatal 5.05E-5
tremors Nos1aptm1b(KOMP)Wtsi HET Female postnatal 5.71E-5

Download data as: TSV XLS


IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415)
Aorta 2 No (2/2)
Bone 2 No
Brain 2 No (2/2)
Brainstem 2 No
Brown adipose tissue 2 No
Cartilage tissue 2 No (2/2)
Cerebellum 2 No (2/2)
Cerebral cortex 2 No (2/2)
Esophagus 2 No (7/415)
Eye 2 No
Gall bladder 2 No (2/2)
Heart 2 No (2/2)
Hippocampus 2 No (2/2)
Hypothalamus 2 No (2/2)
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584)
Liver 2 No
Lower urinary tract 2 No (2/2)
Lung 2 No
Lymph node 2 No
Mammary gland 2 No
Mesenteric lymph node 2 No
Olfactory lobe 2 No (2/2)
Oral epithelium 2 No
Ovary 2 No (1/584) (1/2)
Oviduct 2 No
Pancreas 2 No (5/584)
Parathyroid gland 2 No (2/2)
Peripheral nervous system 2 No
Peyer's patch 2 No
Pituitary gland 2 No
Prostate gland 2 No (12/584) (1/2)
Skeletal muscle 2 No
Skin 2 No
Small intestine 2 No (9/584)
Spinal cord 2 No (2/2)
Spleen 2 No (2/584)
Stomach 2 No (12/584)
Striatum 2 No
Testis 2 No (2/584)
Thymus 2 No
Thyroid gland 2 No (15/584) (2/2)
Trachea 2 No (2/2)
Urinary bladder 2 No
Uterus 2 No
Vas deferens 2 No (15/388)
Vascular system 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse
    respiratory system
    endocrine system
    digestive system
    cardiovascular system
    nervous system
    set of connective tissues
    reproductive system
    exocrine system
    urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab

Associated Images

Associated Images
  • Adult LacZ: LacZ Images Wholemount
    10 Images
  • X-ray: XRay Images Dorso Ventral
    2 Images
  • X-ray: XRay Images Forepaw
    2 Images
  • X-ray: XRay Images Lateral Orientation
    2 Images
  • X-ray: XRay Images Skull Lateral Orientation
    2 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    2 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Nos1aptm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Nos1aptm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)