Gene: Eci3

Order

Name enoyl-Coenzyme A delta isomerase 3

Synonyms 1810022C23Rik

Status ES CellsMice
tm1b
Mice
tm1a
phenotype data available

Links MGI:1916373    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Eci3

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Eci3 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
decreased circulating LDL cholesterol level Eci3tm1b(EUCOMM)Wtsi HOM Female Male postnatal 5.38E-5
decreased CD4-positive, alpha beta T cell number Eci3tm1b(EUCOMM)Wtsi HOM Female Male postnatal 5.39E-5
decreased T cell number Eci3tm1b(EUCOMM)Wtsi HOM Female Male postnatal 9.83E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No
Aorta 2 No
Blood vessel 2 No
Bone 2 No
Brain 2 No
Brainstem 2 No
Brown adipose tissue 2 No
Cartilage tissue 2 No
Cerebellum 2 No
Cerebral cortex 2 No
Eye 2 No
Gall bladder 2 No
Heart 2 No
Hippocampus 2 No
Hypothalamus 2 No
Kidney 2 No (18/584)
Large intestine 2 No (10/584)
Liver 2 No
Lower urinary tract 2 No
Lung 2 No
Lymph node 2 No
Mammary gland 2 No
Esophagus 2 No
Olfactory lobe 2 No
Ovary 2 No (1/584)
Oviduct 2 No
Pancreas 2 No (5/584)
Parathyroid gland 2 No
Peripheral nervous system 2 No
Peyer's patch 2 No
Pituitary gland 2 No
Prostate gland 2 No (12/584)
Skeletal muscle tissue 2 No
Skin 2 No
Small intestine 2 No (9/584)
Spinal cord 2 No
Spleen 2 No (2/584)
Stomach 2 No (12/584)
Striatum 2 No
Testis 2 No (2/584) (1/2)
Thymus 2 No
Thyroid gland 2 No (15/584)
Trachea 2 No
Uterus 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse reproductive system trunk
No expression image was found for this adult tab
No expression data was found for this embryo tab


Secondary lacZ Expression Data
postnatal mouse (1)
  • Eci3tm1b(EUCOMM)Wtsi
    testis, HET, Male, WTSI
reproductive system (1)
  • Eci3tm1b(EUCOMM)Wtsi
    testis, HET, Male, WTSI
trunk (1)
  • Eci3tm1b(EUCOMM)Wtsi
    testis, HET, Male, WTSI

Associated Images

Associated Images
  • X-ray: XRay Images Dorso Ventral
    43 Images
  • X-ray: XRay Images Skull Lateral Orientation
    14 Images
  • X-ray: XRay Images Lateral Orientation
    28 Images
  • X-ray: XRay Images Forepaw
    14 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    15 Images
  • Eye Morphology: Images Slit Lamp
    2 Images
  • Anti-nuclear antibody assay
    6 Images
  • Eye Morphology: Images Ophthalmoscopy
    1 Images
  • DSS Histology
    8 Images
Legacy Phenotype Associated Images
Xray (71)
  • Eci3tm1b(EUCOMM)Wtsi
    HOM, Female, WTSI
  • Eci3tm1b(EUCOMM)Wtsi
    HOM, Female, WTSI
  • Eci3tm1b(EUCOMM)Wtsi
    HOM, Female, WTSI
  • Eci3tm1b(EUCOMM)Wtsi
    HOM, Female, WTSI
  • Eci3tm1b(EUCOMM)Wtsi
    HOM, Male, WTSI

show all 71 images

Eye Morphology (3)
  • Eci3tm1b(EUCOMM)Wtsi
    persistence of hyaloid vascular system, HOM, Female, WTSI
  • Eci3tm1b(EUCOMM)Wtsi
    mydriasis, HOM, Female, WTSI
  • Eci3tm1b(EUCOMM)Wtsi
    Fused cornea and lens, HOM, Female, WTSI

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Eci3tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Eci3tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene