Gene: Nmb

Order

Name neuromedin B

Synonyms 3110023K12Rik

Status ES CellsMice
tm1.1
Mice
tm1
phenotype data available

Links MGI:1915289    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Nmb

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Nmb data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
decreased startle reflex Nmbtm1.1(KOMP)Vlcg HOM Female Male postnatal 8.48E-7
decreased prepulse inhibition Nmbtm1.1(KOMP)Vlcg HOM Male postnatal 1.05E-5
increased prepulse inhibition Nmbtm1.1(KOMP)Vlcg HOM Female postnatal 1.05E-5
abnormal sleep behavior Nmbtm1.1(KOMP)Vlcg HOM Female Male postnatal 2.03E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (5/393) (2/2)
Aorta 2 No (1/562)
Brain 2 No (6/562) (2/2)
Brainstem 2 No (4/562) (2/2)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/562) (1/2)
Cerebellum 2 No (4/562) (2/2)
Cerebral cortex 2 No (5/562) (2/2)
Epididymis 2 No (4/106) (1/2)
Esophagus 2 No (2/393) (2/2)
Eye 2 No (1/562)
Heart 2 No (3/562) (2/2)
Hippocampus 2 No (5/562) (2/2)
Hypothalamus 2 No (4/562)
Kidney 2 No (20/562) (2/2)
Large intestine 2 No (12/562) (2/2)
Liver 2 No
Lower urinary tract 2 No (3/562)
Lung 2 No (3/562) (2/2)
Lymph node 2 No (1/562)
Mammary gland 2 No
Midbrain 2 No (2/2)
Olfactory lobe 2 No (4/393) (2/2)
Ovary 2 No (1/562) (1/2)
Oviduct 2 No (2/562) (1/2)
Pancreas 2 No (6/562) (2/2)
Peripheral nervous system 2 No (3/562)
Peyer's patch 2 No (1/393)
Pituitary gland 2 No (1/562) (2/2)
Prostate gland 2 No (5/562)
Skeletal muscle 2 No
Skin 2 No (1/562)
Small intestine 2 No (11/562) (2/2)
Spinal cord 2 No (3/562) (1/2)
Spleen 2 No (4/562) (2/2)
Stomach 2 No (9/562) (2/2)
Striatum 2 No (4/562)
Submandibular gland 2 No (1/104) (2/2)
Testis 2 No (4/562) (1/2)
Thalamus 2 No
Thymus 2 No (2/2)
Thyroid gland 2 No (16/562) (1/2)
Trachea 2 No (3/562)
Urinary bladder 2 No
Uterus 2 No (2/562) (1/2)
Vascular system 2 No (1/393)
Vesicular gland 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system
    postnatal mouse
    respiratory system
    digestive system
    cardiovascular system
    nervous system
    set of connective tissues
    reproductive system
    immune system
    exocrine system
    trunk
    urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2 (6/482)
Dorsal root ganglion 2 (1/45)
Ear 2 (1/482) (1/3)
Embryo 2 (1/482) (2/3)
Eye 2 (1/482)
Foot 2 (1/482)
Forebrain 2 (1/482)
Forelimb 2 (1/482)
Fronto-nasal process 2 (1/46)
Hand 2 (1/482)
Head 2 (5/482)
Heart 2 (1/482)
Hindbrain 2 (6/482)
Hindlimb 2 (1/482)
Liver 2 (1/482)
Lung 2 (1/482) Image Only
Mandibular process 2 (1/482)
Maxillary process 2 (1/482)
Metanephros 1 (1/44) Image Only
Midbrain 2 (1/482)
Nose 2 (1/47)
Oral cavity 2 (1/482)
Skin 2 (1/482)
Spinal cord 2 (1/46)
Tail 2 (1/482)
Tail somite 2 (1/482)


Associated Images

Associated Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    9 Images
  • Sleep Wake: Wake state (bmp file)
    6 Images
  • X-ray: XRay Images Forepaw
    9 Images
  • X-ray: XRay Images Skull Lateral Orientation
    9 Images
  • X-ray: XRay Images Lateral Orientation
    9 Images
  • X-ray: XRay Images Dorso Ventral
    9 Images
  • Embryo LacZ: LacZ images wholemount
    12 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Nmbtm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette)
Vector
Gene
Nmbtm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene
Nmbtm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene