Gene: Nacc2

Order

Name nucleus accumbens associated 2, BEN and BTB (POZ) domain containing

Synonyms
  • C030048H19Rik
  • 0610020I02Rik
  • Btbd14a

Status ES CellsMice
tm2a
Mice
tm2b
phenotype data available

Links MGI:1915241    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Nacc2

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Nacc2 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal epidermal immune compartment Nacc2tm2b(EUCOMM)Wtsi HOM Female Male postnatal 0.0
abnormal coat appearance Nacc2tm2b(EUCOMM)Wtsi HOM Male postnatal 3.61E-8
decreased grip strength Nacc2tm2b(EUCOMM)Wtsi HOM Female Male postnatal 4.66E-6

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No
Aorta 2 No (1/562)
Blood vessel 2 No
Bone 2 No (1/539)
Brain 2 No (6/562)
Brainstem 2 No (4/562)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/562)
Cerebellum 2 No (4/562)
Cerebral cortex 2 No (5/562)
Eye 2 No (1/562)
Gall bladder 2 No
Heart 2 No (3/562)
Hippocampus 2 No (5/562)
Hypothalamus 2 No (4/562)
Kidney 2 No (20/562)
Large intestine 2 No (12/562)
Liver 2 No
Lower urinary tract 2 No (3/562)
Lung 2 No (3/562)
Lymph node 2 No (1/562)
Mammary gland 2 No
Esophagus 2 No
Olfactory lobe 2 No
Ovary 2 No (1/562)
Oviduct 2 No (2/562)
Pancreas 2 No (6/562)
Parathyroid gland 2 No (2/540)
Peripheral nervous system 2 No (3/562)
Peyer's patch 2 No
Pituitary gland 2 No (1/562)
Prostate gland 2 No (5/562)
Skeletal muscle tissue 2 No
Skin 2 No (1/562)
Small intestine 2 No (11/562)
Spinal cord 2 No (3/562)
Spleen 2 No (4/562)
Stomach 2 No (9/562)
Striatum 2 No (4/562)
Testis 2 No (4/562) (1/2)
Thymus 2 No
Thyroid gland 2 No (16/562)
Trachea 2 No (3/562)
Uterus 2 No (2/562)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse reproductive system trunk
No expression image was found for this adult tab
No expression data was found for this embryo tab


Secondary lacZ Expression Data
postnatal mouse (1)
  • Nacc2tm2b(EUCOMM)Wtsi
    testis, HET, Male, WTSI
reproductive system (1)
  • Nacc2tm2b(EUCOMM)Wtsi
    testis, HET, Male, WTSI
trunk (1)
  • Nacc2tm2b(EUCOMM)Wtsi
    testis, HET, Male, WTSI

Associated Images

Associated Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    13 Images
  • X-ray: XRay Images Dorso Ventral
    39 Images
  • X-ray: XRay Images Lateral Orientation
    26 Images
  • X-ray: XRay Images Skull Lateral Orientation
    13 Images
  • X-ray: XRay Images Forepaw
    13 Images
  • Eye Morphology: Images Slit Lamp
    5 Images
  • DSS Histology
    8 Images
  • Anti-nuclear antibody assay
    6 Images
Legacy Phenotype Associated Images
Xray (65)
  • Nacc2tm2b(EUCOMM)Wtsi
    HOM, Female, WTSI
  • Nacc2tm2b(EUCOMM)Wtsi
    HOM, Female, WTSI
  • Nacc2tm2b(EUCOMM)Wtsi
    HOM, Male, WTSI
  • Nacc2tm2b(EUCOMM)Wtsi
    HOM, Male, WTSI
  • Nacc2tm2b(EUCOMM)Wtsi
    HOM, Male, WTSI

show all 65 images

Eye Morphology (5)
  • Nacc2tm2b(EUCOMM)Wtsi
    abnormal placement of pupils, HOM, Male, WTSI
  • Nacc2tm2b(EUCOMM)Wtsi
    abnormal placement of pupils, HOM, Female, WTSI
  • Nacc2tm2b(EUCOMM)Wtsi
    fused cornea and lens, HOM, Female, WTSI
  • Nacc2tm2b(EUCOMM)Wtsi
    abnormal placement of pupils, HOM, Female, WTSI
  • Nacc2tm2b(EUCOMM)Wtsi
    abnormal cornea morphology, HOM, Female, WTSI
Dysmorphology (2)
  • Nacc2tm2b(EUCOMM)Wtsi
    abnormal hair texture, HOM, Male, WTSI
  • Nacc2tm2b(EUCOMM)Wtsi
    tail, kinked tail, HOM, Male, WTSI

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Nacc2tm2a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Nacc2tm2b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Nacc2tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene