Gene: Daam1

Order

Name dishevelled associated activator of morphogenesis 1

Synonyms
  • 2310028E21Rik
  • 1700066F09Rik

Status ES CellsMice
tm1b
Mice
tm1a
phenotype data available

Links MGI:1914596    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Daam1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Daam1 data for that phenotype.

Embryo Data: 3D Embryo Imaging
Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
embryonic lethality prior to tooth bud stage Daam1tm1b(EUCOMM)Hmgu HOM Female Male embryonic day 12.5 0.0
prenatal lethality prior to heart atrial septation Daam1tm1b(EUCOMM)Hmgu HOM Female Male embryonic day 14.5 0.0
preweaning lethality, complete penetrance Daam1tm1b(EUCOMM)Hmgu HOM Female Male n/a 0.0
increased blood urea nitrogen level Daam1tm1b(EUCOMM)Hmgu HET Female Male postnatal 3.18E-7
increased fasted circulating glucose level Daam1tm1b(EUCOMM)Hmgu HET Male postnatal 7.89E-6
increased circulating iron level Daam1tm1b(EUCOMM)Hmgu HET Female postnatal 1.45E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415)
Aorta 2 No (2/2)
Bone 2 No
Brain 2 No (2/2)
Brainstem 2 No (1/2)
Brown adipose tissue 2 No
Cartilage tissue 2 No (2/2)
Cerebellum 2 No (2/2)
Cerebral cortex 2 No
Esophagus 2 No (7/415) (2/2)
Eye 2 No (2/2)
Gall bladder 2 No
Heart 2 No (2/2)
Hippocampus 2 No
Hypothalamus 2 No (2/2)
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584) (2/2)
Liver 2 No
Lower urinary tract 2 No (2/2)
Lung 2 No (2/2)
Lymph node 2 No
Mammary gland 2 No
Olfactory lobe 2 No
Oral epithelium 2 No (2/2)
Ovary 2 No (1/584) (1/2)
Oviduct 2 No (1/2)
Pancreas 2 No (5/584)
Parathyroid gland 2 No (2/2)
Peripheral nervous system 2 No
Peyer's patch 2 No
Pituitary gland 2 No
Prostate gland 2 No (12/584)
Skeletal muscle 2 No
Skin 2 No (2/2)
Small intestine 2 No (9/584) (2/2)
Spinal cord 2 No (2/2)
Spleen 2 No (2/584)
Stomach 2 No (12/584) (2/2)
Striatum 2 No
Testis 2 No (2/584) (1/2)
Thymus 2 No (2/2)
Thyroid gland 2 No (15/584)
Trachea 2 No (2/2)
Uterus 2 No (1/2)
Vascular system 2 No (2/2)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    respiratory system
    endocrine system
    digestive system
    cardiovascular system
    set of connective tissues
    reproductive system
    trunk
    postnatal mouse
    nervous system
    sensory organ
    immune system
    integumental system
    urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2 (6/485) (4/4)
Ear 2 (1/485) (1/4)
Embryo 2 (1/485) (4/4)
Eye 2 (1/485) (4/4)
Foot 2 (1/485) (3/4)
Forebrain 2 (1/485) (4/4)
Forelimb 2 (1/485) (3/4)
Hand 2 (1/485) (3/4)
Head 2 (5/485) (4/4)
Heart 2 (1/485) (2/4)
Hindbrain 2 (6/485) (4/4)
Hindlimb 2 (1/485) (3/4)
Liver 2 (1/485) (2/4)
Lung 2 (1/485) (2/4)
Mandibular process 2 (1/485) (1/4)
Maxillary process 2 (1/485) (1/4)
Midbrain 2 (1/485) (4/4)
Oral cavity 2 (1/485) (1/4)
Skin 2 (1/485) (1/4)
Tail 2 (1/485) (4/4)
Tail somite 2 (1/485) (4/4)


Associated Images

Associated Images
  • X-ray: XRay Images Dorso Ventral
    10 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    9 Images
  • X-ray: XRay Images Lateral Orientation
    10 Images
  • Adult LacZ: LacZ Images Wholemount
    20 Images
  • Embryo LacZ: LacZ images wholemount
    8 Images
  • Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
    4 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Daam1tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Daam1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene