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Gene: Plin3 MGI:1914155

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Not currently registered for phenotyping at IMPC

Phenotyping is currently not planned for a knockout strain of this gene.

Gene Summary

Name:
perilipin 3
Synonyms:
Tip47,  1300012C15Rik,  M6prbp1

Order Alleles

IMPC Data Collections

  • No Body Weight Data
  • No Embryo Imaging Data
  • No Viability Data

IMPC Phenotype Summary

Significant
Not Significant
Not tested

View all our phenotype data below

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Plin3 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Plin3 by phenotypic similarity.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Obesity
Decreased resting energy expenditure OMIM:601665
Idiopathic Congenital Hypothyroidism
Umbilical hernia, Hypothermia ORPHA:95717
Rigidity And Multifocal Seizure Syndrome, Lethal Neonatal
Joint contracture, Inguinal hernia, Hypothermia OMIM:614498
Primary Erythromelalgia
Hypothermia ORPHA:90026
Obesity Due To Sim1 Deficiency
Increased resting energy expenditure ORPHA:369873
Riboflavin Deficiency
Hypothermia OMIM:615026
Spontaneous Periodic Hypothermia
Hypothermia ORPHA:29822
Developmental And Epileptic Encephalopathy 78
Hypothermia OMIM:618557
Congenital Hypothyroidism Due To Maternal Intake Of Antithyroid Drugs
Umbilical hernia, Hypothermia ORPHA:226313
2-Methylbutyryl-Coa Dehydrogenase Deficiency
Hypothermia OMIM:610006
Familial Thyroid Dyshormonogenesis
Umbilical hernia, Hypothermia ORPHA:95716
Coenzyme Q10 Deficiency, Primary, 5
Hypothermia OMIM:614654
Mitochondrial Dna Depletion Syndrome 9 (Encephalomyopathic Type With Methylmalonic Aciduria)
Hypothermia OMIM:245400
Mitochondrial Complex Iv Deficiency, Nuclear Type 13
Hypothermia OMIM:616501
Sudden Infant Death-Dysgenesis Of The Testes Syndrome
Hypothermia ORPHA:168593
Isolated Thyroid-Stimulating Hormone Deficiency
Hypercholesterolemia, Umbilical hernia, Hypothermia ORPHA:90674
Menkes Disease
Hypothermia OMIM:309400
Hypotonia, Hypoventilation, Impaired Intellectual Development, Dysautonomia, Epilepsy, And Eye Abnormalities
Hip contracture, Elbow flexion contracture, Hypothermia OMIM:618493
Timothy Syndrome
Hypothermia OMIM:601005
Genetic Transient Congenital Hypothyroidism
Umbilical hernia, Hypothermia ORPHA:226316
Very Long Chain Acyl-Coa Dehydrogenase Deficiency
Hypothermia, Increased circulating free fatty acid level ORPHA:26793
Carnitine-Acylcarnitine Translocase Deficiency
Cyanosis, Hypothermia ORPHA:159
Meningococcal Meningitis
Hypothermia ORPHA:33475
Hypothyroidism Due To Tsh Receptor Mutations
Umbilical hernia, Hypothermia ORPHA:90673
Sudden Infant Death With Dysgenesis Of The Testes Syndrome
Hypothermia OMIM:608800
Congenital Enterovirus Infection
Hypothermia ORPHA:292
Menkes Disease
Inguinal hernia, Hypothermia, Atypical scarring of skin, Hernia, Umbilical hernia, Chondrocalcinosis ORPHA:565
Alacrimia-Choreoathetosis-Liver Dysfunction Syndrome
Corneal scarring, Achilles tendon contracture, Limb joint contracture, Decreased resting energy e... ORPHA:404454
Adult-Onset Autosomal Dominant Leukodystrophy
Flexion contracture, Hypothermia ORPHA:99027
Fatal Infantile Lactic Acidosis With Methylmalonic Aciduria
Flexion contracture, Hypothermia ORPHA:17
Ethylene Glycol Poisoning
Cyanosis, Hypothermia ORPHA:31826
Mitochondrial Complex Iii Deficiency, Nuclear Type 10
Hypothermia OMIM:618775
Combined Oxidative Phosphorylation Deficiency 37
Hypothermia OMIM:618329
Occipital Horn Syndrome
Inguinal hernia, Femoral hernia, Scarring, Hypothermia, Hiatus hernia, Atypical scarring of skin,... ORPHA:198
Mitochondrial Dna Depletion Syndrome 3 (Hepatocerebral Type)
Hypothermia OMIM:251880
3-Hydroxy-3-Methylglutaric Aciduria
Hypothermia ORPHA:20
Tbck-Related Intellectual Disability Syndrome
Hypothermia ORPHA:488632
Mitochondrial Dna-Associated Leigh Syndrome
Abnormality of Krebs cycle metabolism, Hypothermia ORPHA:255210
Dopamine Beta-Hydroxylase Deficiency
Hypothermia ORPHA:230
Alexander Disease
Hypothermia ORPHA:58
Rapid-Onset Childhood Obesity-Hypothalamic Dysfunction-Hypoventilation-Autonomic Dysregulation Syndrome
Hyperlipidemia, Cyanosis, Hypothermia ORPHA:293987
Hypothyroidism, Congenital, Nongoitrous, 2
Umbilical hernia, Hypothermia OMIM:218700
Hypothyroidism Due To Deficient Transcription Factors Involved In Pituitary Development Or Function
Umbilical hernia, Hypothermia ORPHA:226307
Methylmalonic Acidemia With Homocystinuria, Type Cblc
Hypothermia ORPHA:79282
Neuroleptic Malignant Syndrome
Hypothermia ORPHA:94093
Hereditary Sensory And Autonomic Neuropathy Type 4
Corneal scarring, Fasciitis, Hypothermia, Atypical scarring of skin ORPHA:642
Pura-Related Severe Neonatal Hypotonia-Seizures-Encephalopathy Syndrome
Uterine prolapse, Hypothermia ORPHA:438213
Sarcoidosis
Scarring, Hypothermia ORPHA:797
Marburg Hemorrhagic Fever
Hypothermia ORPHA:99826

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Plin3

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Plin3.

No publications found that use IMPC mice or data for Plin3.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

MGI Allele Allele Type Produced
Plin3tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) ES Cells
Plin3tm1e(EUCOMM)Hmgu Targeted, non-conditional allele ES Cells
Plin3tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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