Gene: Akap10

Order

Name A kinase (PRKA) anchor protein 10

Synonyms
  • 1500031L16Rik
  • D-AKAP2
  • B130049N18Rik

Status ES CellsMice
tm1.1
Mice
tm1
phenotype data available

Links MGI:1890218    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Subviable

Phenotype associations for Akap10

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Akap10 data for that phenotype.

Embryo Data: 3D Embryo Imaging
Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal craniofacial morphology Akap10tm1.1(KOMP)Vlcg HET Male embryonic day 12.5 0.0
abnormal embryo size Akap10tm1.1(KOMP)Vlcg HET Male embryonic day 12.5 0.0
abnormal embryo size Akap10tm1.1(KOMP)Vlcg HET Male embryonic day 9.5 0.0
abnormal eye morphology Akap10tm1.1(KOMP)Vlcg HET Female Male embryonic day 12.5 0.0
abnormal liver size Akap10tm1.1(KOMP)Vlcg HET Male embryonic day 12.5 0.0
embryonic growth retardation Akap10tm1.1(KOMP)Vlcg HET Male embryonic day 9.5 0.0
embryonic lethality prior to tooth bud stage Akap10tm1.1(KOMP)Vlcg HOM Female Male embryonic day 12.5 0.0
preweaning lethality, incomplete penetrance Akap10tm1.1(KOMP)Vlcg HOM Female Male n/a 0.0
increased hematocrit Akap10tm1.1(KOMP)Vlcg HET Female Male postnatal 4.69E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415) (2/2)
Aorta 2 No
Bone 1 No (1/1)
Brain 2 No (2/2)
Brainstem 2 No (2/2)
Brown adipose tissue 2 No (1/2)
Cartilage tissue 2 No (2/2)
Cerebellum 2 No
Cerebral cortex 2 No (2/2)
Esophagus 2 No (7/415)
Eye 2 No (2/2)
Heart 2 No (2/2)
Hippocampus 2 No (2/2)
Hypothalamus 2 No (2/2)
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584) (2/2)
Liver 2 No (2/2)
Lower urinary tract 2 No (2/2)
Lung 2 No (2/2)
Lymph node 2 No
Mammary gland 2 No
Olfactory lobe 2 No (2/2)
Ovary 2 No (1/584) (1/2)
Oviduct 2 No (1/2)
Pancreas 2 No (5/584) (2/2)
Peripheral nervous system 2 No
Peyer's patch 2 No
Pituitary gland 2 No
Prostate gland 2 No (12/584) (1/2)
Skeletal muscle 2 No (2/2)
Skin 2 No (2/2)
Small intestine 2 No (9/584) (2/2)
Spinal cord 2 No (2/2)
Spleen 2 No (2/584)
Stomach 2 No (12/584) (2/2)
Striatum 2 No
Testis 2 No (2/584)
Thymus 2 No
Thyroid gland 2 No (15/584) (2/2)
Trachea 2 No (2/2)
Uterus 2 No
Vascular system 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system
    respiratory system
    digestive system
    cardiovascular system
    set of connective tissues
    reproductive system
    musculoskeletal system
    adipose tissue
    trunk
    postnatal mouse
    nervous system
    sensory organ
    exocrine system
    integumental system
    urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2 (1/51) (2/2)
Brain 6 (6/485) (2/7)
Central nervous system ganglion 2 (1/51) (2/2)
Ear 6 (1/485) (2/7)
Embryo 6 (1/485) (2/7)
Eye 6 (1/485) (2/7)
Foot 6 (1/485) (2/7)
Forebrain 6 (1/485) (2/7)
Forelimb 6 (1/485) (2/7)
Gut 2 (1/50) (2/2)
Hand 6 (1/485) (2/7)
Head 6 (5/485) (2/7)
Heart 6 (1/485) (2/7)
Hindbrain 6 (6/485) (2/7)
Hindlimb 6 (1/485) (2/7)
Liver 6 (1/485) (2/7)
Lung 6 (1/485) (2/7)
Mandibular process 6 (1/485) (2/7)
Maxillary process 6 (1/485) (2/7)
Midbrain 6 (1/485) (2/7)
Nose 2 (1/51) (2/2)
Oral cavity 6 (1/485) (2/7)
2 (7/25) (2/2)
Skeleton 2 (1/51) (2/2)
Skin 6 (1/485) (2/7)
Spinal cord 2 (1/50) (2/2)
Tail 6 (1/485) (2/7)
Tail somite 6 (1/485) (2/7)
Trachea 2 (1/50) (2/2)
Urinary system 2 (1/50) (2/2)


Associated Images

Associated Images
  • Embryo LacZ: LacZ images wholemount
    20 Images
  • X-ray: XRay Images Lateral Orientation
    11 Images
  • X-ray: XRay Images Dorso Ventral
    9 Images
  • Adult LacZ: LacZ Images Section
    28 Images

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Akap10tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette)
Vector
Gene
Fixed Tissue
Akap10tm48590(L1L2_Bact_P)
Vector
Gene
Akap10tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene