Gene: Angptl4
Name angiopoietin-like 4
Synonyms
- FIAF
- NG27
- BK89
- HFARP
Status
ES CellsMice
tm1aMice
tm1bphenotype data available
Links MGI:1888999 Ensembl Gene Ensembl Orthologs
Viability Homozygous - Viable
Phenotype associations for Angptl4
All Phenotypes Summary
Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Angptl4 data for that phenotype.
Significant Phenotypes
| System | Phenotype | Allele | Zyg | Sex | Life Stage | P Value | Data |
|---|---|---|---|---|---|---|---|
|
|
decreased circulating triglyceride level | Angptl4tm1b(EUCOMM)Hmgu | HOM |
|
postnatal | 6.64E-6 | |
|
|
increased red blood cell distribution width | Angptl4tm1b(EUCOMM)Hmgu | HOM |
|
postnatal | 7.63E-6 | |
|
|
decreased neutrophil cell number | Angptl4tm1b(EUCOMM)Hmgu | HOM |
|
postnatal | 9.68E-5 |
Expression
IMPC lacZ Expression Data
Show expression table
Expression No Expression No Tissue Available Ambiguous
Show Wildtype Expression
| Anatomy | #HET Specimens | HOM Images? | WT Expr | Mutant Expr | Images |
|---|---|---|---|---|---|
| Adrenal gland | 2 | No | (5/393) | ||
| Aorta | 2 | No | (1/562) | ||
| Bone | 2 | No | (1/539) | ||
| Brain | 2 | No | (6/562) | (2/2) | |
| Brainstem | 2 | No | (4/562) | (2/2) | |
| Brown adipose tissue | 2 | No | (2/2) | ||
| Cartilage tissue | 2 | No | (1/562) | ||
| Cerebellum | 2 | No | (4/562) | ||
| Cerebral cortex | 2 | No | (5/562) | ||
| Esophagus | 2 | No | (2/393) | ||
| Eye | 2 | No | (1/562) | ||
| Gall bladder | 2 | No | |||
| Heart | 2 | No | (3/562) | ||
| Hippocampus | 2 | No | (5/562) | ||
| Hypothalamus | 2 | No | (4/562) | (2/2) | |
| Kidney | 2 | No | (20/562) | (2/2) | |
| Large intestine | 2 | No | (12/562) | ||
| Liver | 2 | No | |||
| Lower urinary tract | 2 | No | (3/562) | (2/2) | |
| Lung | 2 | No | (3/562) | ||
| Lymph node | 2 | No | (1/562) | ||
| Mammary gland | 2 | No | (1/2) | ||
| Olfactory lobe | 2 | No | (4/393) | (2/2) | |
| Oral epithelium | 2 | No | |||
| Ovary | 2 | No | (1/562) | (1/2) | |
| Oviduct | 2 | No | (2/562) | (1/2) | |
| Pancreas | 2 | No | (6/562) | ||
| Parathyroid gland | 2 | No | (2/540) | ||
| Peripheral nervous system | 2 | No | (3/562) | (2/2) | |
| Peyer's patch | 2 | No | (1/393) | ||
| Pituitary gland | 2 | No | (1/562) | ||
| Prostate gland | 2 | No | (5/562) | ||
| Skeletal muscle | 2 | No | |||
| Skin | 2 | No | (1/562) | (2/2) | |
| Small intestine | 2 | No | (11/562) | ||
| Spinal cord | 2 | No | (3/562) | ||
| Spleen | 2 | No | (4/562) | ||
| Stomach | 2 | No | (9/562) | ||
| Striatum | 2 | No | (4/562) | ||
| Testis | 2 | No | (4/562) | (1/2) | |
| Thymus | 2 | No | |||
| Thyroid gland | 2 | No | (16/562) | (1/2) | |
| Trachea | 2 | No | (3/562) | ||
| Uterus | 2 | No | (2/562) | (1/2) | |
| Vascular system | 2 | No | (1/393) | (2/2) | |
| White adipose tissue | 2 | No | (2/2) |
No expression image was found for this adult tab
Expression No Expression No Tissue Available Ambiguous
| Anatomy | #HET Specimens | WT Expr | Mutant Expr | Images |
|---|---|---|---|---|
| Brain | 2 | (6/440) | (3/4) | |
| Ear | 2 | (1/440) | ||
| Embryo | 2 | (1/440) | (3/4) | |
| Eye | 2 | (1/440) | ||
| Foot | 2 | |||
| Forebrain | 2 | (1/440) | (1/4) | |
| Forelimb | 2 | (1/440) | ||
| Hand | 2 | |||
| Head | 2 | (5/440) | (3/4) | |
| Heart | 2 | (1/440) | ||
| Hindbrain | 2 | (5/440) | (1/4) | |
| Hindlimb | 2 | (1/440) | ||
| Liver | 2 | (1/440) | ||
| Lung | 2 | (1/440) | ||
| Mandibular process | 2 | (1/440) | ||
| Maxillary process | 2 | (1/440) | ||
| Midbrain | 2 | (1/440) | (3/4) | |
| Oral cavity | 2 | (1/440) | ||
| Skin | 2 | (1/440) | ||
| Tail | 2 | (1/440) | ||
| Tail somite | 2 | (1/440) |
Associated Images
Associated Images
-
X-ray: XRay Images Lateral Orientation
10 Images
-
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
-
X-ray: XRay Images Dorso Ventral
10 Images
-
Adult LacZ: LacZ Images Wholemount
14 Images
-
Embryo LacZ: LacZ images wholemount
8 Images
-
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images
Order Mouse and ES Cells
| Targeting Detail | Product Ordering | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MGI Allele | Allele Type | Type Map Seq | Vector | ES Cell | Mouse | Tissue Enquiry | ||||||
| Angptl4tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) |
|
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| Angptl4tm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (post-Cre) |
|
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