Gene: Angptl4
Name angiopoietin-like 4
Synonyms
- FIAF
- HFARP
- BK89
- NG27
Status
ES CellsMice
tm1aMice
tm1bphenotype data available
Links MGI:1888999 Ensembl Gene Ensembl Orthologs My Genes
Viability Homozygous - Viable
Phenotype associations for Angptl4
All Phenotypes Summary
Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Angptl4 data for that phenotype.
Significant Phenotypes
System | Phenotype | Allele | Zyg | Sex | Life Stage | P Value | Data |
---|---|---|---|---|---|---|---|
|
increased red blood cell distribution width | Angptl4tm1b(EUCOMM)Hmgu | HOM |
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postnatal | 7.63E-6 | |
|
decreased circulating triglyceride level | Angptl4tm1b(EUCOMM)Hmgu | HOM |
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postnatal | 8.72E-6 | |
|
decreased neutrophil cell number | Angptl4tm1b(EUCOMM)Hmgu | HOM |
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postnatal | 9.68E-5 |
Expression
IMPC lacZ Expression Data
Show expression table
Expression No Expression No Tissue Available Ambiguous
Show Wildtype Expression
Anatomy | #HET Specimens | HOM Images? | WT Expr | Mutant Expr | Images |
---|---|---|---|---|---|
Adrenal gland | 2 | No | (5/393) | ||
Aorta | 2 | No | (1/562) | ||
Bone | 2 | No | (1/539) | ||
Brain | 2 | No | (6/562) | (2/2) | |
Brainstem | 2 | No | (4/562) | (2/2) | |
Brown adipose tissue | 2 | No | (2/2) | ||
Cartilage tissue | 2 | No | (1/562) | ||
Cerebellum | 2 | No | (4/562) | ||
Cerebral cortex | 2 | No | (5/562) | ||
Esophagus | 2 | No | (2/393) | ||
Eye | 2 | No | (1/562) | ||
Gall bladder | 2 | No | |||
Heart | 2 | No | (3/562) | ||
Hippocampus | 2 | No | (5/562) | ||
Hypothalamus | 2 | No | (4/562) | (2/2) | |
Kidney | 2 | No | (20/562) | (2/2) | |
Large intestine | 2 | No | (12/562) | ||
Liver | 2 | No | |||
Lower urinary tract | 2 | No | (3/562) | (2/2) | |
Lung | 2 | No | (3/562) | ||
Lymph node | 2 | No | (1/562) | ||
Mammary gland | 2 | No | (1/2) | ||
Olfactory lobe | 2 | No | (4/393) | (2/2) | |
Oral epithelium | 2 | No | |||
Ovary | 2 | No | (1/562) | (1/2) | |
Oviduct | 2 | No | (2/562) | (1/2) | |
Pancreas | 2 | No | (6/562) | ||
Parathyroid gland | 2 | No | (2/540) | ||
Peripheral nervous system | 2 | No | (3/562) | (2/2) | |
Peyer's patch | 2 | No | (1/393) | ||
Pituitary gland | 2 | No | (1/562) | ||
Prostate gland | 2 | No | (5/562) | ||
Skeletal muscle | 2 | No | |||
Skin | 2 | No | (1/562) | (2/2) | |
Small intestine | 2 | No | (11/562) | ||
Spinal cord | 2 | No | (3/562) | ||
Spleen | 2 | No | (4/562) | ||
Stomach | 2 | No | (9/562) | ||
Striatum | 2 | No | (4/562) | ||
Testis | 2 | No | (4/562) | (1/2) | |
Thymus | 2 | No | |||
Thyroid gland | 2 | No | (16/562) | (1/2) | |
Trachea | 2 | No | (3/562) | ||
Uterus | 2 | No | (2/562) | (1/2) | |
Vascular system | 2 | No | (1/393) | (2/2) | |
White adipose tissue | 2 | No | (2/2) |
No expression image was found for this adult tab
Expression No Expression No Tissue Available Ambiguous
Anatomy | #HET Specimens | WT Expr | Mutant Expr | Images |
---|---|---|---|---|
Brain | 2 | (6/482) | (3/4) | |
Ear | 2 | (1/482) | ||
Embryo | 2 | (1/482) | (3/4) | |
Eye | 2 | (1/482) | ||
Foot | 2 | (1/482) | ||
Forebrain | 2 | (1/482) | (1/4) | |
Forelimb | 2 | (1/482) | ||
Hand | 2 | (1/482) | ||
Head | 2 | (5/482) | (3/4) | |
Heart | 2 | (1/482) | ||
Hindbrain | 2 | (6/482) | (1/4) | |
Hindlimb | 2 | (1/482) | ||
Liver | 2 | (1/482) | ||
Lung | 2 | (1/482) | ||
Mandibular process | 2 | (1/482) | ||
Maxillary process | 2 | (1/482) | ||
Midbrain | 2 | (1/482) | (3/4) | |
Oral cavity | 2 | (1/482) | ||
Skin | 2 | (1/482) | ||
Tail | 2 | (1/482) | ||
Tail somite | 2 | (1/482) |
Order Mouse and ES Cells
Targeting Detail | Product Ordering | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
MGI Allele | Allele Type | Type Map Seq | Vector | ES Cell | Mouse | Tissue Enquiry | ||||||
Angptl4tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) |
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Angptl4tm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (post-Cre) |
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