Gene: Angptl4

Name angiopoietin-like 4

Synonyms
  • HFARP
  • BK89
  • FIAF
  • NG27

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:1888999   Ensembl Gene   Ensembl Orthologs

Viability Homozygous - Viable

Phenotype associations for Angptl4

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Angptl4 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
absent optic nerve Angptl4tm1b(EUCOMM)Hmgu HOM Female postnatal 0.0
decreased circulating triglyceride level Angptl4tm1b(EUCOMM)Hmgu HOM Female Male postnatal 4.44E-6
increased red blood cell distribution width Angptl4tm1b(EUCOMM)Hmgu HOM Male postnatal 7.63E-6
decreased bone mineral density Angptl4tm1b(EUCOMM)Hmgu HOM Female Male postnatal 1.32E-5
decreased neutrophil cell number Angptl4tm1b(EUCOMM)Hmgu HOM Male postnatal 9.68E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/354)
Aorta 2 No (2/530)
Bone 2 No (1/515)
Brain 2 No (8/530) (2/2)
Brainstem 2 No (5/530) (2/2)
Brown adipose tissue 2 No (2/2)
Cartilage tissue 2 No (1/530)
Cerebellum 2 No (6/530)
Cerebral cortex 2 No (6/530)
Esophagus 2 No (1/354)
Eye 2 No (1/530)
Gall bladder 2 No
Heart 2 No (4/530)
Hippocampus 2 No (7/530)
Hypothalamus 2 No (5/529) (2/2)
Kidney 2 No (13/530) (2/2)
Large intestine 2 No (7/530)
Liver 2 No
Lower urinary tract 2 No (3/530) (2/2)
Lung 2 No (4/530)
Lymph node 2 No (2/530)
Mammary gland 2 No (1/2)
Olfactory lobe 2 No (3/354) (2/2)
Oral epithelium 2 No
Ovary 2 No (1/530) (1/2)
Oviduct 2 No (1/530) (1/2)
Pancreas 2 No (2/530)
Parathyroid gland 2 No (2/516)
Peripheral nervous system 2 No (4/530) (2/2)
Peyer's patch 2 No (1/354)
Pituitary gland 2 No (2/530)
Prostate gland 2 No (3/530)
Skeletal muscle 2 No
Skin 2 No (2/530) (2/2)
Small intestine 2 No (5/530)
Spinal cord 2 No (5/530)
Spleen 2 No (3/530)
Stomach 2 No (5/530)
Striatum 2 No (6/530)
Testis 2 No (7/530) (1/2)
Thymus 2 No (1/530)
Thyroid gland 2 No (11/530) (1/2)
Trachea 2 No (5/530)
Uterus 2 No (1/530) (1/2)
Vascular system 2 No (1/354) (2/2)
White adipose tissue 2 No (2/2)
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse
    endocrine system
    cardiovascular system
    nervous system
    set of connective tissues
    reproductive system
    adipose tissue
    exocrine system
    integumental system
    trunk
    urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Associated Images

Associated Images
  • X-ray: XRay Images Lateral Orientation
    10 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    10 Images
  • X-ray: XRay Images Dorso Ventral
    10 Images
  • Adult LacZ: LacZ Images Wholemount
    14 Images

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse
Angptl4tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Angptl4tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre)
Vector
Gene